SE8802480L - PROCEDURES FOR PREPARING NUCLEIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING MEDICAL COMPOSITION CONTAINING THEM - Google Patents
PROCEDURES FOR PREPARING NUCLEIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING MEDICAL COMPOSITION CONTAINING THEMInfo
- Publication number
- SE8802480L SE8802480L SE8802480A SE8802480A SE8802480L SE 8802480 L SE8802480 L SE 8802480L SE 8802480 A SE8802480 A SE 8802480A SE 8802480 A SE8802480 A SE 8802480A SE 8802480 L SE8802480 L SE 8802480L
- Authority
- SE
- Sweden
- Prior art keywords
- procedures
- nucleic acid
- preparing
- acid derivatives
- composition containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A method of producing double-stranded nucleic acid derivatives having RNA as the parent body (the total molecular size distribution of which is from 4S to 13S expressed as sedimentation constant value of, alternatively, is such that the derivatives have base numbers in the range 50 to 10,000) including sizing nucleic acid polymers and subsequently combining them. Before combination the sized polymers may be subjected to ion-exchange treatment (to effect a size determination). Such treatment with ion-exchange will also serve to remove pyrogens from nucleic acid derivatives intended for administration by injection.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16743487 | 1987-07-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8802480D0 SE8802480D0 (en) | 1988-07-01 |
| SE8802480L true SE8802480L (en) | 1989-01-04 |
Family
ID=15849635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8802480A SE8802480L (en) | 1987-07-03 | 1988-07-01 | PROCEDURES FOR PREPARING NUCLEIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING MEDICAL COMPOSITION CONTAINING THEM |
Country Status (19)
| Country | Link |
|---|---|
| KR (1) | KR890002226A (en) |
| CN (1) | CN1024556C (en) |
| AT (1) | AT397658B (en) |
| AU (1) | AU1864488A (en) |
| CH (1) | CH676123A5 (en) |
| DE (1) | DE3822406A1 (en) |
| DK (1) | DK369088A (en) |
| ES (1) | ES2007252A6 (en) |
| FI (1) | FI883163A (en) |
| FR (1) | FR2617403B1 (en) |
| GB (1) | GB2207138B (en) |
| HU (1) | HU202250B (en) |
| IL (1) | IL86884A0 (en) |
| IT (1) | IT1224504B (en) |
| NL (1) | NL8801664A (en) |
| NO (1) | NO882922L (en) |
| PT (1) | PT87903B (en) |
| SE (1) | SE8802480L (en) |
| ZA (1) | ZA884698B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963532A (en) * | 1987-11-25 | 1990-10-16 | Hem Research, Inc. | dsRNA-based prevention of viral escape |
| RU2222334C2 (en) | 1998-05-25 | 2004-01-27 | Ниппон Синяку Ко., Лтд. | Method for preparing nucleic acid-containing composite preparation |
| CN1194002C (en) * | 1999-02-15 | 2005-03-23 | 日本新药株式会社 | Shortened-chain polynucleotide and process for the preparation thereof |
| EP2930180B1 (en) * | 2012-12-06 | 2021-11-10 | Kyowa Hakko Bio Co., Ltd. | Double-stranded ribonucleic acid for adjuvants |
| CN117517551A (en) * | 2023-11-03 | 2024-02-06 | 成都迈科康生物科技有限公司 | Method for detecting polyinosinic cell content by adopting high performance liquid chromatography |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ194880A (en) * | 1979-09-17 | 1983-07-15 | Merck & Co Inc | Interferon-inducing composition containing modified polyriboinosinic-polyribocytidylic acid |
-
1988
- 1988-06-27 GB GB8815262A patent/GB2207138B/en not_active Expired - Fee Related
- 1988-06-27 IL IL86884A patent/IL86884A0/en unknown
- 1988-06-29 CN CN88104080A patent/CN1024556C/en not_active Expired - Fee Related
- 1988-06-29 AT AT0169988A patent/AT397658B/en not_active IP Right Cessation
- 1988-06-29 CH CH2467/88A patent/CH676123A5/fr not_active IP Right Cessation
- 1988-06-30 NO NO88882922A patent/NO882922L/en unknown
- 1988-06-30 NL NL8801664A patent/NL8801664A/en not_active Application Discontinuation
- 1988-06-30 ZA ZA884698A patent/ZA884698B/en unknown
- 1988-07-01 IT IT8848147A patent/IT1224504B/en active
- 1988-07-01 FI FI883163A patent/FI883163A/en not_active IP Right Cessation
- 1988-07-01 HU HU883461A patent/HU202250B/en not_active IP Right Cessation
- 1988-07-01 FR FR8808938A patent/FR2617403B1/en not_active Expired - Fee Related
- 1988-07-01 DK DK369088A patent/DK369088A/en not_active Application Discontinuation
- 1988-07-01 PT PT87903A patent/PT87903B/en not_active IP Right Cessation
- 1988-07-01 ES ES8802078A patent/ES2007252A6/en not_active Expired
- 1988-07-01 SE SE8802480A patent/SE8802480L/en not_active Application Discontinuation
- 1988-07-01 AU AU18644/88A patent/AU1864488A/en not_active Abandoned
- 1988-07-01 DE DE3822406A patent/DE3822406A1/en not_active Withdrawn
- 1988-07-02 KR KR1019880008258A patent/KR890002226A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2207138B (en) | 1992-02-05 |
| IL86884A0 (en) | 1988-11-30 |
| HU202250B (en) | 1991-02-28 |
| DK369088A (en) | 1989-01-04 |
| AU1864488A (en) | 1989-04-27 |
| AT397658B (en) | 1994-06-27 |
| GB8815262D0 (en) | 1988-08-03 |
| NO882922L (en) | 1989-01-04 |
| PT87903B (en) | 1995-03-01 |
| ATA169988A (en) | 1993-10-15 |
| KR890002226A (en) | 1989-04-10 |
| FI883163A (en) | 1989-01-04 |
| CH676123A5 (en) | 1990-12-14 |
| SE8802480D0 (en) | 1988-07-01 |
| FI883163A0 (en) | 1988-07-01 |
| HUT48272A (en) | 1989-05-29 |
| IT1224504B (en) | 1990-10-04 |
| DK369088D0 (en) | 1988-07-01 |
| PT87903A (en) | 1989-06-30 |
| DE3822406A1 (en) | 1989-01-12 |
| CN1030424A (en) | 1989-01-18 |
| CN1024556C (en) | 1994-05-18 |
| NO882922D0 (en) | 1988-06-30 |
| FR2617403A1 (en) | 1989-01-06 |
| NL8801664A (en) | 1989-02-01 |
| FR2617403B1 (en) | 1993-05-07 |
| IT8848147A0 (en) | 1988-07-01 |
| ES2007252A6 (en) | 1989-06-01 |
| GB2207138A (en) | 1989-01-25 |
| ZA884698B (en) | 1989-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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