SE8601408L - FUSOGENE LIPOSOMES AND PROCEDURES FOR PREPARING THESE - Google Patents

FUSOGENE LIPOSOMES AND PROCEDURES FOR PREPARING THESE

Info

Publication number
SE8601408L
SE8601408L SE8601408A SE8601408A SE8601408L SE 8601408 L SE8601408 L SE 8601408L SE 8601408 A SE8601408 A SE 8601408A SE 8601408 A SE8601408 A SE 8601408A SE 8601408 L SE8601408 L SE 8601408L
Authority
SE
Sweden
Prior art keywords
liposomes
cell
fusogene
procedures
preparing
Prior art date
Application number
SE8601408A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8601408D0 (en
SE464448B (en
Inventor
A G Gitman
A Loyter
Original Assignee
Int Genetic Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Genetic Sciences filed Critical Int Genetic Sciences
Publication of SE8601408D0 publication Critical patent/SE8601408D0/en
Publication of SE8601408L publication Critical patent/SE8601408L/en
Publication of SE464448B publication Critical patent/SE464448B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Phospholipid vesicles (liposomes) containing a quaternary ammonium hydroxide salt in the membranes of the vesicles are described. The phospholipid vesicles containing the quaternary ammonium hydroxide salt in the vesicle membranes, in addition to their ability to attach to animal and plant cells, will fuse with a cell membrane and induce cell-to-cell fusion, providing a convenient way of transferring a material such as a drug into a cell.
SE8601408A 1985-04-04 1986-03-26 FUSOGEN Phospholipid Vesicle Containing A Quaternary Ammonium Hydroxide Salt In The Membrane And A Procedure For Its Preparation SE464448B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71986285A 1985-04-04 1985-04-04

Publications (3)

Publication Number Publication Date
SE8601408D0 SE8601408D0 (en) 1986-03-26
SE8601408L true SE8601408L (en) 1986-10-05
SE464448B SE464448B (en) 1991-04-29

Family

ID=24891665

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8601408A SE464448B (en) 1985-04-04 1986-03-26 FUSOGEN Phospholipid Vesicle Containing A Quaternary Ammonium Hydroxide Salt In The Membrane And A Procedure For Its Preparation

Country Status (16)

Country Link
JP (1) JPS61274739A (en)
AU (1) AU585330B2 (en)
BE (1) BE904536A (en)
BR (1) BR8601554A (en)
CA (1) CA1262863A (en)
CH (1) CH668005A5 (en)
DE (1) DE3610873A1 (en)
ES (1) ES8802401A1 (en)
FR (1) FR2579891B1 (en)
GB (1) GB2188900B (en)
IL (1) IL78348A (en)
IT (1) IT1189877B (en)
NL (1) NL8600794A (en)
NZ (1) NZ215696A (en)
SE (1) SE464448B (en)
ZA (1) ZA862466B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897355A (en) 1985-01-07 1990-01-30 Syntex (U.S.A.) Inc. N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US5545412A (en) * 1985-01-07 1996-08-13 Syntex (U.S.A.) Inc. N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
JPS63275522A (en) * 1987-05-01 1988-11-14 Terumo Corp Artificial erythrocyte and production thereof
JPH04283207A (en) * 1991-03-13 1992-10-08 Kao Corp Vesicle and polymer vesicle
CA2269697A1 (en) * 1996-10-25 1998-04-30 Monsanto Company Composition and method for treating plants with exogenous chemicals
BR9713322B1 (en) * 1996-10-25 2010-09-08 composition and method for treating plants with exogenous chemical substances.
US20150174068A1 (en) * 2011-09-12 2015-06-25 Cure Ip Holdings, Llc Apparatus, Composition, and Related Methods for Transdermal Delivery of Active Ingredients

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4789633A (en) * 1984-04-19 1988-12-06 University Of Tennessee Research Corporation Fused liposome and acid induced method for liposome fusion
DE3669503D1 (en) * 1985-01-07 1990-04-19 Syntex Inc SURFACE-ACTIVE N- (OMEGA, OMEGA-1-DIALKOXY) - AND N- (OMEGA, OMEGA-1-DIALKENOXY) -ALK-1-YL-N, N, N-TRISUBSTITUTED AMMONIUM COMPOUNDS, THEIR PRODUCTION AND THEIR CONTAINERS.

Also Published As

Publication number Publication date
BR8601554A (en) 1986-12-09
DE3610873A1 (en) 1986-10-09
SE8601408D0 (en) 1986-03-26
NL8600794A (en) 1986-11-03
ES8802401A1 (en) 1988-05-16
CA1262863A (en) 1989-11-14
AU5562286A (en) 1986-10-09
FR2579891A1 (en) 1986-10-10
GB2188900A (en) 1987-10-14
BE904536A (en) 1986-07-31
ZA862466B (en) 1986-11-26
IL78348A (en) 1989-08-15
CH668005A5 (en) 1988-11-30
SE464448B (en) 1991-04-29
JPS61274739A (en) 1986-12-04
NZ215696A (en) 1989-07-27
ES553703A0 (en) 1988-05-16
GB2188900B (en) 1990-04-04
IL78348A0 (en) 1986-07-31
IT1189877B (en) 1988-02-10
GB8608468D0 (en) 1986-05-14
FR2579891B1 (en) 1990-02-02
AU585330B2 (en) 1989-06-15
IT8683340A0 (en) 1986-04-03

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