BE904536A - FUSOGENIC LIPOSOMES AND THEIR MANUFACTURING METHOD. - Google Patents

FUSOGENIC LIPOSOMES AND THEIR MANUFACTURING METHOD.

Info

Publication number
BE904536A
BE904536A BE0/216489A BE216489A BE904536A BE 904536 A BE904536 A BE 904536A BE 0/216489 A BE0/216489 A BE 0/216489A BE 216489 A BE216489 A BE 216489A BE 904536 A BE904536 A BE 904536A
Authority
BE
Belgium
Prior art keywords
cell
manufacturing
membranes
fusogenic liposomes
quaternary ammonium
Prior art date
Application number
BE0/216489A
Other languages
French (fr)
Original Assignee
Internat Genetic Sciences Part
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Internat Genetic Sciences Part filed Critical Internat Genetic Sciences Part
Publication of BE904536A publication Critical patent/BE904536A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells

Abstract

Description de vésicules de phospholipides (limosomes) contenant un sel d'hydroxyde d'ammonium quaternaire dans leurs membranes.Les vésicules de phospholipides contenant le sel d'hydroxyde d'ammonium quaternaire dans leurs membranes, en plus de l'aptitude à se fixer aux cellules, fuseront avec une membrane cellulaire et induiront une fusion cellule à cellule, fournissant ainsi un moyens approprié de transférer dans une cellule une substance telle qu'un médicament.Description of phospholipid vesicles (limosomes) containing a quaternary ammonium hydroxide salt in their membranes. Phospholipid vesicles containing the quaternary ammonium hydroxide salt in their membranes, in addition to the ability to attach to cells, will fuse with a cell membrane and induce cell-to-cell fusion, thereby providing an appropriate means of transferring a substance such as a drug into a cell.

BE0/216489A 1985-04-04 1986-04-02 FUSOGENIC LIPOSOMES AND THEIR MANUFACTURING METHOD. BE904536A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71986285A 1985-04-04 1985-04-04

Publications (1)

Publication Number Publication Date
BE904536A true BE904536A (en) 1986-07-31

Family

ID=24891665

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/216489A BE904536A (en) 1985-04-04 1986-04-02 FUSOGENIC LIPOSOMES AND THEIR MANUFACTURING METHOD.

Country Status (16)

Country Link
JP (1) JPS61274739A (en)
AU (1) AU585330B2 (en)
BE (1) BE904536A (en)
BR (1) BR8601554A (en)
CA (1) CA1262863A (en)
CH (1) CH668005A5 (en)
DE (1) DE3610873A1 (en)
ES (1) ES8802401A1 (en)
FR (1) FR2579891B1 (en)
GB (1) GB2188900B (en)
IL (1) IL78348A (en)
IT (1) IT1189877B (en)
NL (1) NL8600794A (en)
NZ (1) NZ215696A (en)
SE (1) SE464448B (en)
ZA (1) ZA862466B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366737A (en) * 1985-01-07 1994-11-22 Syntex (U.S.A.) Inc. N-[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N,-tetrasubstituted ammonium lipids and uses therefor
US5545412A (en) * 1985-01-07 1996-08-13 Syntex (U.S.A.) Inc. N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
JPS63275522A (en) * 1987-05-01 1988-11-14 Terumo Corp Artificial erythrocyte and production thereof
JPH04283207A (en) * 1991-03-13 1992-10-08 Kao Corp Vesicle and polymer vesicle
HUP9903889A3 (en) * 1996-10-25 2004-07-28 Monsanto Technology Llc St Louis Composition and method for treating plants with exogenous chemicals
JP4155601B2 (en) * 1996-10-25 2008-09-24 モンサント・テクノロジー・エルエルシー Compositions and methods for treating plants with exogenous chemicals
US20150174068A1 (en) * 2011-09-12 2015-06-25 Cure Ip Holdings, Llc Apparatus, Composition, and Related Methods for Transdermal Delivery of Active Ingredients

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4789633A (en) * 1984-04-19 1988-12-06 University Of Tennessee Research Corporation Fused liposome and acid induced method for liposome fusion
NZ214716A (en) * 1985-01-07 1989-04-26 Syntex Inc 1,2-dialkoxy-omega-trialkylammonium cationic surfactants

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366737A (en) * 1985-01-07 1994-11-22 Syntex (U.S.A.) Inc. N-[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N,-tetrasubstituted ammonium lipids and uses therefor
US5545412A (en) * 1985-01-07 1996-08-13 Syntex (U.S.A.) Inc. N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor
US5550289A (en) * 1985-01-07 1996-08-27 Syntex (U.S.A.) Inc. N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N-tetrasubstituted ammonium lipids and uses therefor
US5622712A (en) * 1985-01-07 1997-04-22 Syntex (U.S.A.) Inc. N-[ω, (ω-1)-dialkyloxy]- and N-[ω, (ω-1)-dialkenyloxy]-alk-1-yl-N, N, N-tetrasubstituted ammonium lipids and uses therefor
US6387395B1 (en) 1985-01-07 2002-05-14 Deborah A. Eppstein N-[1, (1-1) -dialkyloxy] - and N- [1, (1-1) -dialkenyloxy]- alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor

Also Published As

Publication number Publication date
GB2188900A (en) 1987-10-14
BR8601554A (en) 1986-12-09
NL8600794A (en) 1986-11-03
CA1262863A (en) 1989-11-14
SE8601408L (en) 1986-10-05
AU585330B2 (en) 1989-06-15
CH668005A5 (en) 1988-11-30
JPS61274739A (en) 1986-12-04
AU5562286A (en) 1986-10-09
IT8683340A0 (en) 1986-04-03
NZ215696A (en) 1989-07-27
IL78348A (en) 1989-08-15
IL78348A0 (en) 1986-07-31
DE3610873A1 (en) 1986-10-09
FR2579891A1 (en) 1986-10-10
SE464448B (en) 1991-04-29
GB8608468D0 (en) 1986-05-14
SE8601408D0 (en) 1986-03-26
GB2188900B (en) 1990-04-04
IT1189877B (en) 1988-02-10
FR2579891B1 (en) 1990-02-02
ES553703A0 (en) 1988-05-16
ZA862466B (en) 1986-11-26
ES8802401A1 (en) 1988-05-16

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: INTERNATIONAL GENETIC SCIENCES PARTNERSHIP

Effective date: 19920430