SE8401064D0 - NEW ISOXAZOLE AND PROCEDURES FOR YOUR RESTORATION - Google Patents

NEW ISOXAZOLE AND PROCEDURES FOR YOUR RESTORATION

Info

Publication number
SE8401064D0
SE8401064D0 SE8401064A SE8401064A SE8401064D0 SE 8401064 D0 SE8401064 D0 SE 8401064D0 SE 8401064 A SE8401064 A SE 8401064A SE 8401064 A SE8401064 A SE 8401064A SE 8401064 D0 SE8401064 D0 SE 8401064D0
Authority
SE
Sweden
Prior art keywords
group
formula
image
restoration
procedures
Prior art date
Application number
SE8401064A
Other languages
Swedish (sv)
Other versions
SE8401064L (en
Inventor
K Lempert
G Doleschall
J Fetter
G Hornyak
J Nyitrai
G Simig
K Zauer
Original Assignee
Richter Gedeon Vegyeszet
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet, Biogal Gyogyszergyar filed Critical Richter Gedeon Vegyeszet
Publication of SE8401064D0 publication Critical patent/SE8401064D0/en
Publication of SE8401064L publication Critical patent/SE8401064L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The invention relates to new isoxazole derivatives of the general formula <IMAGE> wherein X and Y which are the same or different, stand for a nitrile group, an optionally activated carboxylic group, a -CO2Z or -CONRR' group wherein Z represents a C1-6 alkyl group, R and R' represent a hydrogen atom, a phenyl or benzyl group or R and R' together with the nitrogen atom may form a heterocyclic ring, or X and Y together stand for an anhydride group of the formula <IMAGE> By catalytic hydrogenation, the compounds of the formula (I) can be transformed to intermediates for the preparation of thienamycin, a known broad-spectrum antibiotic.
SE8401064A 1983-02-28 1984-02-27 NEW ISOXAZOLES AND PROCEDURES FOR PRODUCING THEREOF SE8401064L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU83661A HU189236B (en) 1983-02-28 1983-02-28 Process for producing new type isoxazoles

Publications (2)

Publication Number Publication Date
SE8401064D0 true SE8401064D0 (en) 1984-02-27
SE8401064L SE8401064L (en) 1984-08-29

Family

ID=10950718

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8401064A SE8401064L (en) 1983-02-28 1984-02-27 NEW ISOXAZOLES AND PROCEDURES FOR PRODUCING THEREOF

Country Status (12)

Country Link
JP (1) JPS59164784A (en)
BE (1) BE899007A (en)
CH (1) CH658655A5 (en)
DE (1) DE3405422A1 (en)
ES (3) ES530121A0 (en)
FR (1) FR2541678A1 (en)
GB (1) GB2135996B (en)
HU (1) HU189236B (en)
IT (1) IT1174498B (en)
NL (1) NL8400575A (en)
PT (1) PT78157B (en)
SE (1) SE8401064L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366987A (en) * 1991-08-22 1994-11-22 Warner-Lambert Company Isoxazolyl-substituted alkyl amide ACAT inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163057A (en) * 1977-12-27 1979-07-31 Sandoz, Inc. Isoxazole-4-carboxamides as tranquilizers, sleep-inducers and muscle relaxants

Also Published As

Publication number Publication date
FR2541678A1 (en) 1984-08-31
ES8604174A1 (en) 1986-01-16
ES8601935A1 (en) 1985-11-16
ES544192A0 (en) 1986-01-16
ES544191A0 (en) 1986-01-16
IT1174498B (en) 1987-07-01
HU189236B (en) 1986-06-30
GB2135996A (en) 1984-09-12
BE899007A (en) 1984-08-27
PT78157A (en) 1984-03-01
CH658655A5 (en) 1986-11-28
PT78157B (en) 1986-05-19
JPS59164784A (en) 1984-09-17
DE3405422A1 (en) 1984-08-30
GB8405001D0 (en) 1984-04-04
GB2135996B (en) 1986-09-10
ES530121A0 (en) 1985-11-16
IT8419806A0 (en) 1984-02-27
SE8401064L (en) 1984-08-29
ES8604175A1 (en) 1986-01-16
NL8400575A (en) 1984-09-17

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