SE8303385D0 - 1,4-DIHYDROPYRIDINE DERIVATIVES, IN OPTICALLY ACTIVE OR IN RACEMATE FORM AND THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS - Google Patents
1,4-DIHYDROPYRIDINE DERIVATIVES, IN OPTICALLY ACTIVE OR IN RACEMATE FORM AND THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONSInfo
- Publication number
- SE8303385D0 SE8303385D0 SE8303385A SE8303385A SE8303385D0 SE 8303385 D0 SE8303385 D0 SE 8303385D0 SE 8303385 A SE8303385 A SE 8303385A SE 8303385 A SE8303385 A SE 8303385A SE 8303385 D0 SE8303385 D0 SE 8303385D0
- Authority
- SE
- Sweden
- Prior art keywords
- optically active
- production
- pharmaceutical compositions
- compounds
- dihydropyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
Compounds having the formula (I) wherein one of the two residues R1 and R2 is the methyl group and the other one is a group selected among isopropyl, n-butyl, isobutyl, cyclopentyl or isopropoxy-ethyl groups and the residue R3 is hydrogen or an optionally substituted alkyl group; these compounds are either in an optically active form when R3 is hydrogen, or in a racemic form or in an optically active form when R3 is an alkyl residue with 1 to 6 atoms of carbon, optionally substituted. Such compounds are used for the treatment of the deficiency of coronaries, cerebro-vascular deficiency, troubles of peripheral circulation, hypertension or asthma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH369282 | 1982-06-15 | ||
CH369382 | 1982-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8303385D0 true SE8303385D0 (en) | 1983-06-14 |
SE8303385L SE8303385L (en) | 1983-12-16 |
Family
ID=25693638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8303385A SE8303385L (en) | 1982-06-15 | 1983-06-14 | 1,4-DIHYDROPYRIDINE DERIVATIVES, OPTICALLY ACTIVE OR RACEMAT FORM AND THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS |
Country Status (19)
Country | Link |
---|---|
AU (1) | AU1575383A (en) |
BE (1) | BE897000A (en) |
CA (1) | CA1208639A (en) |
CH (1) | CH660593A5 (en) |
DE (1) | DE3320616A1 (en) |
DK (1) | DK271183A (en) |
ES (2) | ES8504179A1 (en) |
FI (1) | FI832072L (en) |
FR (1) | FR2528431B1 (en) |
GB (1) | GB2122192B (en) |
HU (1) | HU191853B (en) |
IT (1) | IT1178353B (en) |
NL (1) | NL8302067A (en) |
NZ (1) | NZ204536A (en) |
PH (1) | PH23436A (en) |
PT (1) | PT76870B (en) |
SE (1) | SE8303385L (en) |
WO (1) | WO1984000033A1 (en) |
ZA (1) | ZA834409B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3431152A1 (en) * | 1984-08-24 | 1986-03-06 | Cassella Ag, 6000 Frankfurt | METHOD FOR PRODUCING OPTICALLY ACTIVE, SUBSTITUTED 1,4-DIHYDROPYRIDINE AND THEIR USE AS A MEDICINAL PRODUCT |
GB8428552D0 (en) * | 1984-11-12 | 1984-12-19 | Sandoz Ltd | Organic compounds |
US5260321A (en) * | 1984-11-12 | 1993-11-09 | Sandoz Ltd. | Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins |
DE3447169A1 (en) * | 1984-12-22 | 1986-07-03 | Bayer Ag, 5090 Leverkusen | OPTICALLY ACTIVE NITRODIHYDROPYRIDINE, METHOD FOR THE PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS |
US4920225A (en) * | 1986-12-22 | 1990-04-24 | Laboratoires Syntex S.A. | Resolution of 1,4-dihydropyridine derivatives |
EP0287828A1 (en) * | 1987-03-27 | 1988-10-26 | Byk Gulden Lomberg Chemische Fabrik GmbH | Intermediates and their preparation |
DE4041814A1 (en) * | 1990-12-24 | 1992-07-02 | Byk Gulden Lomberg Chem Fab | METHOD FOR PRODUCING DIHYDROPHYRIDINE CARBONIC ACIDS |
US5135936A (en) * | 1991-03-05 | 1992-08-04 | Marion Merrell Dow Inc. | Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists |
CN100425599C (en) * | 2005-12-31 | 2008-10-15 | 清华大学 | Organic electroluminescent material and its application |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH639659A5 (en) * | 1978-12-18 | 1983-11-30 | Sandoz Ag | NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE. |
DK149855C (en) * | 1977-06-20 | 1987-04-21 | Sandoz Ag | METHOD OF ANALOGY FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES |
DE2949464A1 (en) * | 1978-12-18 | 1980-06-26 | Sandoz Ag | BENZOXADIAZOLES AND BENZOTHIADIAZOLES, THEIR PRODUCTION AND USE |
FI813460L (en) * | 1980-11-10 | 1982-05-11 | Sandoz Ag | NYA 4- (2,1,3-BENZOXADIAZOL-4-YL) -1,4-DIHYDRO-PYRIDIN DERIVATIVES DERAS FRAMSTAELLNINGSFOERFARANDE OCH DESSA INNEHAOLLANDE PHARMACEUTICAL COMPOSITION |
-
1983
- 1983-06-07 FR FR8309551A patent/FR2528431B1/en not_active Expired
- 1983-06-08 FI FI832072A patent/FI832072L/en not_active Application Discontinuation
- 1983-06-08 DE DE3320616A patent/DE3320616A1/en not_active Withdrawn
- 1983-06-09 BE BE1/10806A patent/BE897000A/en not_active IP Right Cessation
- 1983-06-10 NL NL8302067A patent/NL8302067A/en not_active Application Discontinuation
- 1983-06-10 WO PCT/CH1983/000073 patent/WO1984000033A1/en unknown
- 1983-06-10 CH CH688/84A patent/CH660593A5/en not_active IP Right Cessation
- 1983-06-13 NZ NZ204536A patent/NZ204536A/en unknown
- 1983-06-13 GB GB08316054A patent/GB2122192B/en not_active Expired
- 1983-06-13 IT IT48488/83A patent/IT1178353B/en active
- 1983-06-13 CA CA000430300A patent/CA1208639A/en not_active Expired
- 1983-06-13 DK DK271183A patent/DK271183A/en not_active Application Discontinuation
- 1983-06-14 PT PT76870A patent/PT76870B/en unknown
- 1983-06-14 SE SE8303385A patent/SE8303385L/en not_active Application Discontinuation
- 1983-06-14 ES ES523243A patent/ES8504179A1/en not_active Expired
- 1983-06-14 AU AU15753/83A patent/AU1575383A/en not_active Abandoned
- 1983-06-14 PH PH29057A patent/PH23436A/en unknown
- 1983-06-14 HU HU832113A patent/HU191853B/en unknown
- 1983-06-15 ZA ZA834409A patent/ZA834409B/en unknown
-
1984
- 1984-11-30 ES ES538157A patent/ES8604578A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3320616A1 (en) | 1983-12-15 |
AU1575383A (en) | 1983-12-22 |
ZA834409B (en) | 1985-02-27 |
FI832072L (en) | 1983-12-16 |
IT8348488A0 (en) | 1983-06-13 |
WO1984000033A1 (en) | 1984-01-05 |
ES523243A0 (en) | 1985-04-01 |
PT76870B (en) | 1986-02-27 |
FI832072A0 (en) | 1983-06-08 |
CA1208639A (en) | 1986-07-29 |
PH23436A (en) | 1989-08-07 |
GB8316054D0 (en) | 1983-07-20 |
CH660593A5 (en) | 1987-05-15 |
NZ204536A (en) | 1986-09-10 |
ES8504179A1 (en) | 1985-04-01 |
PT76870A (en) | 1983-07-01 |
DK271183D0 (en) | 1983-06-13 |
NL8302067A (en) | 1984-01-02 |
IT1178353B (en) | 1987-09-09 |
FR2528431A1 (en) | 1983-12-16 |
SE8303385L (en) | 1983-12-16 |
GB2122192A (en) | 1984-01-11 |
HU191853B (en) | 1987-04-28 |
GB2122192B (en) | 1985-12-18 |
BE897000A (en) | 1983-12-09 |
ES8604578A1 (en) | 1986-02-01 |
DK271183A (en) | 1983-12-16 |
ES538157A0 (en) | 1986-02-01 |
FR2528431B1 (en) | 1986-01-10 |
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Legal Events
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NAV | Patent application has lapsed |
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