SE8205583D0 - NEW 5-AMINOSISOXAZOLE DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME - Google Patents

NEW 5-AMINOSISOXAZOLE DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME

Info

Publication number
SE8205583D0
SE8205583D0 SE8205583A SE8205583A SE8205583D0 SE 8205583 D0 SE8205583 D0 SE 8205583D0 SE 8205583 A SE8205583 A SE 8205583A SE 8205583 A SE8205583 A SE 8205583A SE 8205583 D0 SE8205583 D0 SE 8205583D0
Authority
SE
Sweden
Prior art keywords
group
alkyl
substituted
phenyl
alkyl group
Prior art date
Application number
SE8205583A
Other languages
Swedish (sv)
Other versions
SE8205583L (en
Inventor
T Tatee
S Kurashige
S Ito
H Miyazaki
A Shiozawa
H Yamanaka
Original Assignee
Nippon Kayaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Kk filed Critical Nippon Kayaku Kk
Publication of SE8205583D0 publication Critical patent/SE8205583D0/en
Publication of SE8205583L publication Critical patent/SE8205583L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds of the general formula <IMAGE> (wherein R1 is a C1-C4 alkyl group or a phenyl group which may be substituted by a C1-C4 alkyl group, a C1-C4 alkoxy group or halogen, R2 is a hydrogen atom, halogen atom, C1-C4 alkyl group or phenyl group, R3 is a hydrogen atom, C1-C5 alkyl group, phenyl group or benzyl group which may be substituted with a halogen atom or C1-C4 alkoxy group, R4 and R5 each independently is a hydrogen atom or C1-C4 alkyl group, one of A and B is a carbonyl group and the other represents a methylene group which may be substituted with a C1-C4 alkyl group or A and B each independently is a methylene group which may be substituted with a C1-C4 alkyl group,and D is a group <IMAGE> (in which R6 is a hydrogen atom or C1-C6 alkyl group and R7 is a C1-C6 alkyl group, cycloalkyl group or benzyl group), morpholino group, hexamethyleneimino group, heptamethyleneimino group, pyrrolidino group which may be substituted with one or more C1-C4 alkyl groups, piperazino group which may be substituted with a C1-C4 alkyl, phenyl or halogenophenyl group, or piperidino group which may be substituted with a phenyl or benzyl group) and their salts are muscle relaxants.
SE8205583A 1981-10-09 1982-09-30 NEW 5-AMINOISOXAZOLD DERIVATIVES AND SETS FOR THEIR PREPARATION SE8205583L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56161206A JPS5862169A (en) 1981-10-09 1981-10-09 Novel 5-aminoisooxazole derivative

Publications (2)

Publication Number Publication Date
SE8205583D0 true SE8205583D0 (en) 1982-09-30
SE8205583L SE8205583L (en) 1983-04-10

Family

ID=15730608

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8205583A SE8205583L (en) 1981-10-09 1982-09-30 NEW 5-AMINOISOXAZOLD DERIVATIVES AND SETS FOR THEIR PREPARATION

Country Status (7)

Country Link
JP (1) JPS5862169A (en)
DE (1) DE3237149A1 (en)
ES (2) ES8402278A1 (en)
FR (1) FR2514354A1 (en)
GB (1) GB2107710A (en)
IT (1) IT8223685A0 (en)
SE (1) SE8205583L (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2022462A1 (en) * 1989-08-04 1991-02-05 Akira Matsubara Aminoketone derivatives and use thereof
US5338857A (en) * 1989-08-04 1994-08-16 Mitsui Toatsu Chemicals Incorporated Aminoketone derivatives of 1,2-oxazole and use thereof
JPH04368375A (en) * 1991-06-17 1992-12-21 Otsuka Pharmaceut Factory Inc Isoxazole derivative
US6544982B1 (en) * 1999-10-29 2003-04-08 Merck & Co., Inc. Thrombin receptor antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2068418A1 (en) * 1969-10-27 1971-08-27 Innothera Lab Sa 2-substd-5-amino isoxazole derivs

Also Published As

Publication number Publication date
IT8223685A0 (en) 1982-10-08
GB2107710A (en) 1983-05-05
SE8205583L (en) 1983-04-10
ES516787A0 (en) 1984-02-01
ES8504156A1 (en) 1985-04-01
ES8402278A1 (en) 1984-02-01
ES526914A0 (en) 1985-04-01
JPS5862169A (en) 1983-04-13
DE3237149A1 (en) 1983-04-21
FR2514354A1 (en) 1983-04-15

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