SE8205107D0 - PYRIDINE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING THESE PYRIDINE DERIVATIVES - Google Patents

PYRIDINE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING THESE PYRIDINE DERIVATIVES

Info

Publication number
SE8205107D0
SE8205107D0 SE8205107A SE8205107A SE8205107D0 SE 8205107 D0 SE8205107 D0 SE 8205107D0 SE 8205107 A SE8205107 A SE 8205107A SE 8205107 A SE8205107 A SE 8205107A SE 8205107 D0 SE8205107 D0 SE 8205107D0
Authority
SE
Sweden
Prior art keywords
pyridine derivatives
aralkyl
carbon atoms
procedures
new compounds
Prior art date
Application number
SE8205107A
Other languages
Swedish (sv)
Other versions
SE441357B (en
SE8205107L (en
Inventor
H J Petersen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of SE8205107D0 publication Critical patent/SE8205107D0/en
Publication of SE8205107L publication Critical patent/SE8205107L/en
Publication of SE441357B publication Critical patent/SE441357B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

The present invention relates to new compounds with the general formula I <IMAGE> or the tautomeric forms thereof in which R stands for a straight or branched, saturated or unsaturated, aliphatic hydrocarbon radical having from 1 to 8 carbon atoms, mono- or bicyclic, carbocyclic aryl or aralkyl, aryl meaning unsubstituted or substituted phenyl or naphthyl, and the alkyl moiety of aralkyl having from 1 to 6 carbon atoms. The new compounds are of low toxicity and have been shown to exert a strong and prolonged antihypertensive effect in various animal species when administered enterally or parenterally, without giving rise to other pharmacodynamic effect.
SE8205107A 1981-09-10 1982-09-08 4-PYRIDINO - CYANOGUANIDE INGREDIENTS, PROCEDURES FOR PREPARING THIS AND A COMPOSITION WITH ANTI-PRESSURING EFFECT SE441357B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8127367 1981-09-10

Publications (3)

Publication Number Publication Date
SE8205107D0 true SE8205107D0 (en) 1982-09-08
SE8205107L SE8205107L (en) 1983-03-11
SE441357B SE441357B (en) 1985-09-30

Family

ID=10524416

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8205107A SE441357B (en) 1981-09-10 1982-09-08 4-PYRIDINO - CYANOGUANIDE INGREDIENTS, PROCEDURES FOR PREPARING THIS AND A COMPOSITION WITH ANTI-PRESSURING EFFECT

Country Status (16)

Country Link
JP (1) JPS5857363A (en)
BE (1) BE894350A (en)
CA (1) CA1177080A (en)
CH (1) CH655500B (en)
DE (1) DE3233380A1 (en)
DK (1) DK157923C (en)
FR (1) FR2512447B1 (en)
GB (1) GB2105331B (en)
GR (1) GR77009B (en)
IE (1) IE54196B1 (en)
IT (1) IT1156515B (en)
LU (1) LU84375A1 (en)
NL (1) NL8203214A (en)
PH (1) PH18596A (en)
SE (1) SE441357B (en)
ZA (1) ZA825997B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371086A (en) * 1991-03-15 1994-12-06 The Green Cross Corporation Aminopyridine compounds
JPH05294935A (en) * 1991-03-15 1993-11-09 Green Cross Corp:The Aminopyridine-based compound
US8686002B2 (en) 2005-08-21 2014-04-01 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as binding partners for 5-HT5 receptors
WO2007022964A2 (en) 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-ht5-receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074955A (en) * 1960-11-30 1963-01-22 Us Vitamin Pharm Corp Pyridylalkyl dicyandiamides and guanylureas
US3329569A (en) * 1962-07-31 1967-07-04 Smith Kline French Lab Hypotensive compositions and methods of producing hypotension
FR2043491A1 (en) * 1969-05-30 1971-02-19 Ugine Kuhlmann Alpha-pyrid-4'-yl-benzylidene-aminoguani- - dines useful as hypotensives and spasmoly-tics
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
US4287346A (en) * 1979-02-16 1981-09-01 Eisai Co., Ltd. Cyanoguanidine derivatives

Also Published As

Publication number Publication date
DK398882A (en) 1983-03-11
PH18596A (en) 1985-08-15
SE441357B (en) 1985-09-30
IE54196B1 (en) 1989-07-19
FR2512447B1 (en) 1985-11-22
IE821918L (en) 1983-03-10
CH655500B (en) 1986-04-30
SE8205107L (en) 1983-03-11
ZA825997B (en) 1983-07-27
GB2105331A (en) 1983-03-23
DE3233380A1 (en) 1983-03-17
GB2105331B (en) 1985-05-01
DK157923C (en) 1990-08-06
LU84375A1 (en) 1983-06-07
BE894350A (en) 1983-03-09
FR2512447A1 (en) 1983-03-11
JPS5857363A (en) 1983-04-05
GR77009B (en) 1984-09-04
IT8268075A0 (en) 1982-09-09
CA1177080A (en) 1984-10-30
IT1156515B (en) 1987-02-04
DK157923B (en) 1990-03-05
NL8203214A (en) 1983-04-05

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