SE8107726L - Tiokarnitiner, forfarande for deras framstellning och farmaceutiska kompositioner, som innehaller desamma - Google Patents

Tiokarnitiner, forfarande for deras framstellning och farmaceutiska kompositioner, som innehaller desamma

Info

Publication number
SE8107726L
SE8107726L SE8107726A SE8107726A SE8107726L SE 8107726 L SE8107726 L SE 8107726L SE 8107726 A SE8107726 A SE 8107726A SE 8107726 A SE8107726 A SE 8107726A SE 8107726 L SE8107726 L SE 8107726L
Authority
SE
Sweden
Prior art keywords
acyl
thiocarnitine
tiokarnitines
procedures
preparation
Prior art date
Application number
SE8107726A
Other languages
English (en)
Other versions
SE448090B (sv
Inventor
M O Tinti
E Quaresima
Witt P De
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of SE8107726L publication Critical patent/SE8107726L/sv
Publication of SE448090B publication Critical patent/SE448090B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/04Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/14Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A01N37/30Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the groups —CO—N< and, both being directly attached by their carbon atoms to the same carbon skeleton, e.g. H2N—NH—CO—C6H4—COOCH3; Thio-analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C325/00Thioaldehydes; Thioketones; Thioquinones; Oxides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/32Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C07C327/34Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups with amino groups bound to the same hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8107726A 1980-12-24 1981-12-22 Tiokarnitiner och farmaceutiska kompositioner som innehaller dessa SE448090B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT50469/80A IT1143906B (it) 1980-12-24 1980-12-24 Tiocarnitine procedimento per la loro preparazione e loro uso terapeutico

Publications (2)

Publication Number Publication Date
SE8107726L true SE8107726L (sv) 1982-06-25
SE448090B SE448090B (sv) 1987-01-19

Family

ID=11273032

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8107726A SE448090B (sv) 1980-12-24 1981-12-22 Tiokarnitiner och farmaceutiska kompositioner som innehaller dessa

Country Status (10)

Country Link
US (1) US4483869A (sv)
JP (1) JPS57171962A (sv)
AT (1) AT376657B (sv)
BE (1) BE891615A (sv)
CH (1) CH657608A5 (sv)
ES (1) ES508259A0 (sv)
FR (1) FR2496655B1 (sv)
GB (1) GB2089799B (sv)
IT (1) IT1143906B (sv)
SE (1) SE448090B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001275165A1 (en) * 2000-06-01 2001-12-11 Ashni Naturaceuticals, Inc. Treatment of side effects associated with alcohol consumption
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
US20080090942A1 (en) * 2006-05-31 2008-04-17 George Hovorka Tamper evident paint having microcapsules containing signal indicators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2217846A (en) * 1938-03-18 1940-10-15 Gen Aniline & Film Corp Condensation products of betainelike constitution and a process of preparing them

Also Published As

Publication number Publication date
ATA540581A (de) 1984-05-15
SE448090B (sv) 1987-01-19
US4483869A (en) 1984-11-20
FR2496655B1 (fr) 1985-07-05
ES8300696A1 (es) 1982-11-16
CH657608A5 (it) 1986-09-15
GB2089799A (en) 1982-06-30
JPS57171962A (en) 1982-10-22
JPH0116829B2 (sv) 1989-03-27
ES508259A0 (es) 1982-11-16
FR2496655A1 (fr) 1982-06-25
GB2089799B (en) 1984-12-12
BE891615A (fr) 1982-04-16
IT1143906B (it) 1986-10-29
IT8050469A0 (it) 1980-12-24
AT376657B (de) 1984-12-27

Similar Documents

Publication Publication Date Title
GB2037745B (en) Diphenylbutyl - piperazinecarboxamides
ES2085865T3 (es) Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean.
ES505960A0 (es) Un procedimiento para la obtencion de un derivado acilico sustituido del compuesto acido 1,2,3,4-tetrahidro-3-isoqui- nolein-carboxilico
ES514240A0 (es) Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados.
DE3775882D1 (de) Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeuren ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
ZA817696B (en) N-substituted omega-(2-oxo-4-imidazolin-1-yl)alcanoic acids,salts and esters thereof,process for producing the same and these active agents containing pharmaceutical compounds
SE7714374L (sv) 1,4-dihydropyridinforbindelser
BE876067A (fr) Nouveaux acides lactame-n-acetiques et leurs amides, leurs procedes de preparation et compositions therapeutiques
FI834702A (fi) Nya nitroalifatiska foereningar, deras framstaellningsfoerfarande och anvaendning.
SE7609748L (sv) Sett att framstella vinylcyklopropankarboxylatestras
SE8107726L (sv) Tiokarnitiner, forfarande for deras framstellning och farmaceutiska kompositioner, som innehaller desamma
SE8106628L (sv) Ny substitutionsprodukt av glycin, sett for dess framstellning och farmaceutiska kompositioner derav
SE7411243L (sv)
SE7701187L (sv) Nya piperazinderivat och sett att framstella desamma
DE3371627D1 (en) Acetylsalicylic acid thioesters, a process for their preparation and pharmaceutical compositions containing them
SE7608203L (sv) Forfarande for framstellning av substituerade difenylsulfider
SE8201955L (sv) Merkaptoacyl-karnitiner, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma
SE7909514L (sv) Nya halofenyl-pyridyl-allylaminderivat
ES8307736A1 (es) &#34;un procedimiento para la preparacion de esteres de mercapto acil-carnitina&#34;.
SE8302045D0 (sv) Furanderivat
GR79558B (sv)
SE8200649L (sv) Polycykliska foreningar innehallande en dubbelbindning i d-ringen, sett for deras framstellning och farmaceutiska beredningar innehallande dem
MX157221A (es) Procedimiento para preparar derivados de delta 1,3,5-3-cloro-pregnano
SE8204791L (sv) Sett att framstella alkoxivinkaminsyraestrar och alkoxiapovinkaminsyraestrar
SE7709852L (sv) Sett att framstella ett nytt pyrimidinderivat

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8107726-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8107726-5

Format of ref document f/p: F