SE8002910L - 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar - Google Patents

3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar

Info

Publication number
SE8002910L
SE8002910L SE8002910A SE8002910A SE8002910L SE 8002910 L SE8002910 L SE 8002910L SE 8002910 A SE8002910 A SE 8002910A SE 8002910 A SE8002910 A SE 8002910A SE 8002910 L SE8002910 L SE 8002910L
Authority
SE
Sweden
Prior art keywords
preparation
chronic obstructive
treatment
sup
dialkylxantines
Prior art date
Application number
SE8002910A
Other languages
English (en)
Swedish (sv)
Inventor
P G Kjellin
C G A Persson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Priority to SE8002910A priority Critical patent/SE8002910L/xx
Priority to AT81850039T priority patent/ATE10099T1/de
Priority to DE8181850039T priority patent/DE3166893D1/de
Priority to EP81850039A priority patent/EP0038784B1/en
Priority to ZA00811729A priority patent/ZA811729B/xx
Priority to CA000373230A priority patent/CA1156229A/en
Priority to PH25455A priority patent/PH16264A/en
Priority to NO811161A priority patent/NO811161L/no
Priority to IE769/81A priority patent/IE51106B1/en
Priority to DK168281AA priority patent/DK151631B/da
Priority to DD81229229A priority patent/DD158400A5/de
Priority to GR64702A priority patent/GR82347B/el
Priority to NZ196829A priority patent/NZ196829A/en
Priority to AU69555/81A priority patent/AU543122B2/en
Priority to ES501400A priority patent/ES8203088A1/es
Priority to PT72881A priority patent/PT72881B/pt
Priority to FI811212A priority patent/FI69465C/fi
Priority to PL1981230737A priority patent/PL134762B1/pl
Priority to HU811020A priority patent/HU185254B/hu
Priority to JP5724181A priority patent/JPS56166191A/ja
Publication of SE8002910L publication Critical patent/SE8002910L/xx
Priority to US06/523,731 priority patent/US4546182A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SE8002910A 1980-04-18 1980-04-18 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar SE8002910L (sv)

Priority Applications (21)

Application Number Priority Date Filing Date Title
SE8002910A SE8002910L (sv) 1980-04-18 1980-04-18 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar
AT81850039T ATE10099T1 (de) 1980-04-18 1981-03-09 3,8-dialkylxanthine, verfahren zu ihrer herstellung und diese enthaltende zusammensetzungen.
DE8181850039T DE3166893D1 (en) 1980-04-18 1981-03-09 3,8-dialkylxanthines, processes for their preparation and compositions containing them
EP81850039A EP0038784B1 (en) 1980-04-18 1981-03-09 3,8-dialkylxanthines, processes for their preparation and compositions containing them
ZA00811729A ZA811729B (en) 1980-04-18 1981-03-16 3,8-dialkyixanthines, their preparation and use
CA000373230A CA1156229A (en) 1980-04-18 1981-03-17 3.8-dialkylxanthines, processes for their preparation, composition and methods for the treatment of chronic obstructive airway disease and cardiovascular diseases
PH25455A PH16264A (en) 1980-04-18 1981-04-01 3,8-dialkylxanthines,their compositions and methods for the treatment of chromic obstructive airway disease and cardiovascular diseases
NO811161A NO811161L (no) 1980-04-18 1981-04-03 3,8-dialkylxantiner og fremgangsmaate for deres fremstilling
IE769/81A IE51106B1 (en) 1980-04-18 1981-04-08 3,8-dialkylxanthines,processes for their preparation and compositions containing them
DK168281AA DK151631B (da) 1980-04-18 1981-04-14 Analogifremgangsmaade til fremstilling af 3,8-dialkylxantiner.
DD81229229A DD158400A5 (de) 1980-04-18 1981-04-14 Verfahren zur herstellung von 3,8-dialkylxanthinen
GR64702A GR82347B (xx) 1980-04-18 1981-04-15
NZ196829A NZ196829A (en) 1980-04-18 1981-04-15 Certain 3,8-disubstituted-3,7-dihydro-1h-purine-2,6-diones
AU69555/81A AU543122B2 (en) 1980-04-18 1981-04-15 Purines
ES501400A ES8203088A1 (es) 1980-04-18 1981-04-15 Un metodo para la preparacion de 3,8-dialcohilxantinas
PT72881A PT72881B (en) 1980-04-18 1981-04-16 Process for preparing 3,8-dialkylxanthines and pharmaceutical compositions thereof useful for the treatment of chronic obstructive airway disease and cardiovascular diseases
FI811212A FI69465C (fi) 1980-04-18 1981-04-16 Foerfarande foer framstaellning av farmakologiskt aktiva 3,8-dialkylxantiner
PL1981230737A PL134762B1 (en) 1980-04-18 1981-04-17 Method of obtaining novel 3,8-dialkyloxantines
HU811020A HU185254B (en) 1980-04-18 1981-04-17 Process for preparing 3,8-dialkyl-xanthines
JP5724181A JPS56166191A (en) 1980-04-18 1981-04-17 3,8-dialkylxanthines and manufacture
US06/523,731 US4546182A (en) 1980-04-18 1983-08-16 3,8-Dialkylxanthines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8002910A SE8002910L (sv) 1980-04-18 1980-04-18 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar

Publications (1)

Publication Number Publication Date
SE8002910L true SE8002910L (sv) 1981-10-19

Family

ID=20340763

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8002910A SE8002910L (sv) 1980-04-18 1980-04-18 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar

Country Status (21)

Country Link
US (1) US4546182A (xx)
EP (1) EP0038784B1 (xx)
JP (1) JPS56166191A (xx)
AT (1) ATE10099T1 (xx)
AU (1) AU543122B2 (xx)
CA (1) CA1156229A (xx)
DD (1) DD158400A5 (xx)
DE (1) DE3166893D1 (xx)
DK (1) DK151631B (xx)
ES (1) ES8203088A1 (xx)
FI (1) FI69465C (xx)
GR (1) GR82347B (xx)
HU (1) HU185254B (xx)
IE (1) IE51106B1 (xx)
NO (1) NO811161L (xx)
NZ (1) NZ196829A (xx)
PH (1) PH16264A (xx)
PL (1) PL134762B1 (xx)
PT (1) PT72881B (xx)
SE (1) SE8002910L (xx)
ZA (1) ZA811729B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
IT1229195B (it) * 1989-03-10 1991-07-25 Poli Ind Chimica Spa Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
WO1990012797A1 (en) * 1989-04-19 1990-11-01 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Sulfer-containing xanthine derivatives as adenosin antagonists
CA2030112A1 (en) * 1989-11-24 1991-05-25 Yasuo Ito Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same
US5366977A (en) * 1992-09-29 1994-11-22 The United States Of America, As Represented By The Department Of Health And Human Services Method of treating cystic fibrosis using 8-cyclopentyl-1,3-dipropylxanthine or xanthine amino congeners
DE4311538C1 (de) * 1993-04-07 1994-10-06 Boehringer Ingelheim Kg Verfahren zur Herstellung von 1,3-Dimethyl-4,5-diaminouracil
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53890B2 (xx) * 1972-04-22 1978-01-12
CA1077932A (en) * 1976-03-31 1980-05-20 Berlex Laboratories, Inc. Xanthine compounds and method of treating bronchospastic and allergic diseases
US4089959A (en) * 1976-03-31 1978-05-16 Cooper Laboratories, Inc. Long-acting xanthine bronchodilators and antiallergy agents
SE416810C (sv) * 1977-10-14 1982-07-19 Draco Ab Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
SE7810946L (sv) * 1978-10-20 1980-04-21 Draco Ab Metod att behandla kronisk obstruktiv luftvegssjukdom

Also Published As

Publication number Publication date
NO811161L (no) 1981-10-19
AU6955581A (en) 1981-10-22
PL134762B1 (en) 1985-09-30
PL230737A1 (xx) 1982-03-29
JPS56166191A (en) 1981-12-21
ES501400A0 (es) 1982-02-16
NZ196829A (en) 1984-12-14
DE3166893D1 (en) 1984-12-06
DK151631B (da) 1987-12-21
PT72881A (en) 1981-05-01
HU185254B (en) 1984-12-28
IE51106B1 (en) 1986-10-01
EP0038784B1 (en) 1984-10-31
DD158400A5 (de) 1983-01-12
PT72881B (en) 1983-03-29
EP0038784A2 (en) 1981-10-28
ES8203088A1 (es) 1982-02-16
GR82347B (xx) 1984-12-13
AU543122B2 (en) 1985-04-04
PH16264A (en) 1983-08-23
FI811212L (fi) 1981-10-19
EP0038784A3 (en) 1982-01-20
FI69465C (fi) 1986-02-10
DK168281A (da) 1981-10-19
CA1156229A (en) 1983-11-01
ZA811729B (en) 1982-04-28
FI69465B (fi) 1985-10-31
US4546182A (en) 1985-10-08
IE810796L (en) 1981-10-18
ATE10099T1 (de) 1984-11-15

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