SE7903300L - DERIVATIVES OF PYRROLIDINCARBOXALDEHYDE AND PIPERIDINKARBOXALDEHYDE AND INTERMEDIATE PRODUCTS THEREFORE - Google Patents

DERIVATIVES OF PYRROLIDINCARBOXALDEHYDE AND PIPERIDINKARBOXALDEHYDE AND INTERMEDIATE PRODUCTS THEREFORE

Info

Publication number
SE7903300L
SE7903300L SE7903300A SE7903300A SE7903300L SE 7903300 L SE7903300 L SE 7903300L SE 7903300 A SE7903300 A SE 7903300A SE 7903300 A SE7903300 A SE 7903300A SE 7903300 L SE7903300 L SE 7903300L
Authority
SE
Sweden
Prior art keywords
group
derivatives
hydrogen atom
pyrrolidincarboxaldehyde
piperidinkarboxaldehyde
Prior art date
Application number
SE7903300A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE426819B (en
Inventor
S I Natarajan
M A Ondetti
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/509,602 external-priority patent/US3944600A/en
Priority claimed from US05/896,420 external-priority patent/US4206122A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of SE7903300L publication Critical patent/SE7903300L/en
Publication of SE426819B publication Critical patent/SE426819B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to derivatives of pyrrolidine carboxyaldehyde and piperidine carboxyaldehyde, together with intermediates for their preparation, having the general formula <IMAGE> where R is a hydrogen atom, a lower alkanoyl group or a group with the formula <IMAGE> where R1 is a hydrogen atom or a lower alkyl group, R2 is a hydrogen atom or a hydroxyl group, R3 is a hydroxymethyl group, a di-(lower alkoxy)-methyl group or a formyl group, and n has the value of 1 or 2, together with their bisulphite addition compounds. The above products can be used as antihypertensive agents.
SE7903300A 1974-09-30 1979-04-12 Derivatives of pyrrolidine carboxyaldehyde and piperidine carboxyaldehyde, together with intermediates for their preparation SE426819B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/509,602 US3944600A (en) 1973-12-20 1974-09-30 Indenylidene-3-acetic acid process for preparing indene acetic acids
US05/896,420 US4206122A (en) 1978-04-14 1978-04-14 Derivatives of pyrrolidinecarboxaldehyde and piperidinecarboxaldehyde and intermediates therefor

Publications (2)

Publication Number Publication Date
SE7903300L true SE7903300L (en) 1979-12-13
SE426819B SE426819B (en) 1983-02-14

Family

ID=27056604

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7903300A SE426819B (en) 1974-09-30 1979-04-12 Derivatives of pyrrolidine carboxyaldehyde and piperidine carboxyaldehyde, together with intermediates for their preparation

Country Status (1)

Country Link
SE (1) SE426819B (en)

Also Published As

Publication number Publication date
SE426819B (en) 1983-02-14

Similar Documents

Publication Publication Date Title
YU48390B (en) NEW 2-ANYLINOPYRIMIDINE DERIVATIVES, A PROCEDURE FOR THEIR MANUFACTURING AND THE DESTINATION MEANS CONTAINING THESE DERIVATIVES
ES470209A1 (en) Mevalonolactone derivatives
ES8603242A1 (en) Nitromethylene derivatives, intermediates, and process for their preparation as insecticides.
SE7902794L (en) NEW CARBOSTYRIL DERIVATIVES AND PROCEDURES FOR MANUFACTURING THEREOF
SE8401134D0 (en) PROCEDURE FOR THE PREPARATION OF DIHYDRO-CYCLOSPORIN D
FI820281L (en) FREQUENCY COMPOSITION FOR 2-PENEMICAL COMPOSITION WITH FRAMEWORK FOR 2-PENEMICAL COMPOSITION OF THE EUROPEAN PHARMACEUTICAL FORM
PT87275A (en) PROCESS FOR THE PREPARATION OF A REPUGNANT COMPOSITION OF INSECTS AND ACARIDS CONTAINING SUBSTITUTED BY PRODUCT OF ALPHA OMEGA-AMINOALCOHOLS AND OF CERTAINS ALPHA OMEGA-AMINOALCOHOLS REPLACED
ES8200679A1 (en) Carbostyril derivatives, and antihistaminic agents containing the same
ES8506629A1 (en) Pyridine derivatives.
SE7602144L (en) QUATER IMIDAZOLIUM ASSOCIATIONS
SE8305422L (en) ASSOCIATIONS WITH PHARMACOLOGICAL EFFECTS, OTHER THAN ANALGETIC EFFECTS
DK211283A (en) BENZOTHIAZOLINE COMPOUNDS
SE7606847L (en) 10- / 3 (4- (P-FLUOROBENZOYL) PIPERIDINYL) PROPYL / PHENOTIAZINES
AR241243A1 (en) 1-phenyl-1-oxymine-haloalkyl new derivatives, procedure for its preparation and compositions containing the same.
GB1390715A (en) Coumarin derivatives
SE7903300L (en) DERIVATIVES OF PYRROLIDINCARBOXALDEHYDE AND PIPERIDINKARBOXALDEHYDE AND INTERMEDIATE PRODUCTS THEREFORE
IE790771L (en) 1,2-disubstituted pyrrolidine and piperidine compounds.
DK148804C (en) METHOD FOR PREPARING 1,2,3,4-TETRAHYDROQUINOLIN-4-ONER
ES531933A0 (en) A PROCEDURE FOR PREPARING AN IMIDAZOLINONE DERIVATIVE
ES8400743A1 (en) 1-Phenylindazol-3-one compounds, process and intermediates for their preparation and medicines containing these compounds.
ES456400A1 (en) Thienothiazine derivatives
SE8005493L (en) 4- (HAFTALENYLOXI) PIPERIDINE DERIVATIVES
SE8301785L (en) SET TO MAKE 2-THIOPHENIC ACETIC ACID DERIVATIVES AND INTERMEDIATES REQUIRED FOR THEIR PREPARATION
GB1352089A (en) Bis-styryltriazoles their use for the optical brightening of organic materials and processes for their manufacture
SE7706693L (en) METHODS OF PRODUCING HYDRAZINOPYRIDAZINE DERIVATIVES

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7903300-7

Effective date: 19921108

Format of ref document f/p: F