SE7713471L - NEW ORGANIC ASSOCIATIONS, THEIR PREPARATION AND USE - Google Patents
NEW ORGANIC ASSOCIATIONS, THEIR PREPARATION AND USEInfo
- Publication number
- SE7713471L SE7713471L SE7713471A SE7713471A SE7713471L SE 7713471 L SE7713471 L SE 7713471L SE 7713471 A SE7713471 A SE 7713471A SE 7713471 A SE7713471 A SE 7713471A SE 7713471 L SE7713471 L SE 7713471L
- Authority
- SE
- Sweden
- Prior art keywords
- hydrogen
- carbon atoms
- preparation
- new organic
- associations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
The invension provides compounds of formula I, I wherein R1 is, for example, hydrogen or alkanoyl of 1 to 20 carbon atoms; R2 is, for example, hydrogen, hydroxy, alkanoyl of 1 to 20 carbon atoms, CF3SO2NH or CC13SO2NH; R3 is hydrogen or, when R2 is chlorine, R3 may also be chlorine; R4 is, for example, hydrogen, alkyl of 1 to 4 carbon atoms or cycloalkyl of 3 to 8 carbon atoms; and R6 is, for example, hydrogen, alkyl of 1 to 4 carbon atoms or, together with R5, a -(CH2)4-, -(CH2)5 or (CH2)6-group, which compounds possess pharmacological activity, for example in she treatment of cardiac diseases and Parkinson's disease.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1535376 | 1976-12-07 | ||
CH8277 | 1977-01-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE7713471L true SE7713471L (en) | 1978-06-08 |
Family
ID=25683446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7713471A SE7713471L (en) | 1976-12-07 | 1977-11-29 | NEW ORGANIC ASSOCIATIONS, THEIR PREPARATION AND USE |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS5384955A (en) |
AT (1) | AT366361B (en) |
CA (1) | CA1105475A (en) |
DE (1) | DE2752659A1 (en) |
DK (1) | DK527877A (en) |
ES (1) | ES464747A1 (en) |
FI (1) | FI773595A (en) |
FR (1) | FR2373513A1 (en) |
GB (1) | GB1597140A (en) |
IE (1) | IE45929B1 (en) |
IL (1) | IL53533A (en) |
NL (1) | NL7713364A (en) |
NZ (1) | NZ185884A (en) |
PH (1) | PH13932A (en) |
PT (1) | PT67365B (en) |
SE (1) | SE7713471L (en) |
SU (1) | SU927110A3 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980000251A1 (en) * | 1978-07-14 | 1980-02-21 | American Hospital Supply Corp | Derivatives of 2-amino-6,7-dihydroxytetrahydronaphthalene(adtn) |
US4314082A (en) * | 1978-07-14 | 1982-02-02 | American Hospital Supply Corporation | Derivatives of 2-amino-6,7-dihydroxytetrahydro naphthalene (ADTN) |
DE3062971D1 (en) | 1979-09-14 | 1983-06-09 | Sandoz Ag | Derivatives of tetraline, their preparation and medicaments containing these compounds |
EP0033789B1 (en) * | 1980-01-30 | 1984-03-07 | American Hospital Supply Corporation | 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof |
SE8004002L (en) * | 1980-05-29 | 1981-11-30 | Arvidsson Folke Lars Erik | THERAPEUTICALLY APPLICABLE TETRALIN DERIVATIVES |
IL65501A (en) * | 1981-05-08 | 1986-04-29 | Astra Laekemedel Ab | 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them |
JPS58500714A (en) * | 1981-05-11 | 1983-05-06 | ア−ヴイツツソン,フオルケ・ラルス−エリ−ク | Therapeutically useful tetralin derivatives 3, processes for the preparation of such compounds and pharmaceutical formulations |
US4402974A (en) | 1981-06-23 | 1983-09-06 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4455317A (en) * | 1981-06-23 | 1984-06-19 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4559359A (en) * | 1981-06-23 | 1985-12-17 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
US4578403A (en) * | 1981-06-23 | 1986-03-25 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
IT1218322B (en) * | 1982-06-10 | 1990-04-12 | Chiesi Farma Spa | 1,2,3,4-TETRAIDRONAFTALENE DERIVATIVES, PREPARATION PROCEDURE AND RELATED PHARMACEUTICAL COMPOSITIONS |
US4500545A (en) * | 1982-11-16 | 1985-02-19 | Eli Lilly And Company | Hydroxyaminotetralincarboxamides |
US4448990A (en) * | 1982-11-16 | 1984-05-15 | Eli Lilly And Company | Hydroxyaminotetralincarboxamides |
US4743618A (en) * | 1983-01-03 | 1988-05-10 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
US5177112A (en) * | 1983-01-03 | 1993-01-05 | Whitby Research, Inc. | Substituted 2-aminotetralins |
US4564628A (en) * | 1983-01-03 | 1986-01-14 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
US4657925A (en) * | 1984-08-13 | 1987-04-14 | Nelson Research & Development Co. | Method and compositions for reducing the intraocular pressure of mammals |
US4722933A (en) * | 1985-12-20 | 1988-02-02 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
GB2157950B (en) * | 1984-05-04 | 1988-11-02 | Nelson Res & Dev | Selective d-2 dopamine receptor agonist |
CA1331191C (en) | 1988-03-25 | 1994-08-02 | Bengt Ronny Andersson | Therapeutically useful tetralin derivatives |
US5214156A (en) * | 1988-03-25 | 1993-05-25 | The Upjohn Company | Therapeutically useful tetralin derivatives |
US5225596A (en) * | 1989-01-09 | 1993-07-06 | The Upjohn Company | Halo substituted aminotetralins |
JP2931986B2 (en) * | 1989-02-17 | 1999-08-09 | 武田薬品工業株式会社 | Aralkylamine derivatives |
SE8901889D0 (en) * | 1989-05-26 | 1989-05-26 | Astra Ab | NOVEL 8-SUBSTITUTED-2-AMINOTETRALINES |
US5380748A (en) * | 1991-03-07 | 1995-01-10 | Zeria Pharmaceutical Co., Ltd. | Trialkylamine derivative and ameliorant for digestive tract movement containing the same |
CA2255612A1 (en) * | 1996-05-31 | 1997-12-04 | Pharmacia & Upjohn Company | Aryl substituted cyclic amines as selective dopamine d3 ligands |
IT1294931B1 (en) | 1997-09-22 | 1999-04-23 | Sigma Tau Ind Farmaceuti | DERIVATIVES OF 2-AMINOTETHRALIN PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, ACTIVE IN THE |
AR054363A1 (en) * | 2005-05-23 | 2007-06-20 | Astrazeneca Ab | COMPOUNDS THAT DISPLAY MODULATORY ACTIVITY IN THE 5-HYDROXY-TRIPTAMINE 6 RECEIVER |
AU2012276179B2 (en) * | 2011-06-27 | 2015-09-24 | Shan Dong Luye Pharmaceutical Co., Ltd. | Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1017359A (en) * | 1972-07-03 | 1977-09-13 | Frederic P. Hauck | Substituted cyclic polymethylene phenols |
-
1977
- 1977-11-25 DE DE19772752659 patent/DE2752659A1/en not_active Ceased
- 1977-11-28 FI FI773595A patent/FI773595A/en not_active Application Discontinuation
- 1977-11-28 DK DK527877A patent/DK527877A/en not_active Application Discontinuation
- 1977-11-29 SE SE7713471A patent/SE7713471L/en not_active Application Discontinuation
- 1977-12-02 NL NL7713364A patent/NL7713364A/en not_active Application Discontinuation
- 1977-12-05 IE IE2462/77A patent/IE45929B1/en unknown
- 1977-12-05 GB GB50477/77A patent/GB1597140A/en not_active Expired
- 1977-12-05 PT PT67365A patent/PT67365B/en unknown
- 1977-12-05 IL IL53533A patent/IL53533A/en unknown
- 1977-12-05 ES ES464747A patent/ES464747A1/en not_active Expired
- 1977-12-06 AT AT0871977A patent/AT366361B/en not_active IP Right Cessation
- 1977-12-06 FR FR7736662A patent/FR2373513A1/en active Granted
- 1977-12-06 JP JP14648577A patent/JPS5384955A/en active Granted
- 1977-12-06 CA CA292,457A patent/CA1105475A/en not_active Expired
- 1977-12-06 NZ NZ185884A patent/NZ185884A/en unknown
- 1977-12-06 SU SU772549950A patent/SU927110A3/en active
- 1977-12-07 PH PH20543A patent/PH13932A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPS5384955A (en) | 1978-07-26 |
DK527877A (en) | 1978-06-08 |
NL7713364A (en) | 1978-06-09 |
PT67365B (en) | 1979-09-20 |
FR2373513B1 (en) | 1980-08-22 |
IL53533A0 (en) | 1978-03-10 |
AT366361B (en) | 1982-04-13 |
ATA871977A (en) | 1981-08-15 |
DE2752659A1 (en) | 1978-06-08 |
SU927110A3 (en) | 1982-05-07 |
PT67365A (en) | 1978-01-01 |
CA1105475A (en) | 1981-07-21 |
GB1597140A (en) | 1981-09-03 |
ES464747A1 (en) | 1979-01-01 |
FI773595A (en) | 1978-06-08 |
JPS6214540B2 (en) | 1987-04-02 |
IE45929L (en) | 1978-06-07 |
PH13932A (en) | 1980-11-04 |
FR2373513A1 (en) | 1978-07-07 |
IL53533A (en) | 1982-07-30 |
IE45929B1 (en) | 1982-12-29 |
NZ185884A (en) | 1980-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 7713471-6 |