FR2450835A2 - TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION - Google Patents

TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION

Info

Publication number
FR2450835A2
FR2450835A2 FR7906055A FR7906055A FR2450835A2 FR 2450835 A2 FR2450835 A2 FR 2450835A2 FR 7906055 A FR7906055 A FR 7906055A FR 7906055 A FR7906055 A FR 7906055A FR 2450835 A2 FR2450835 A2 FR 2450835A2
Authority
FR
France
Prior art keywords
tetrahydroalstonin
derivatives
therapeutic application
application
bopi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7906055A
Other languages
French (fr)
Other versions
FR2450835B2 (en
Inventor
Henry Najer
Bernard Mompon
Braham Shroot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7811026A external-priority patent/FR2422664A1/en
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7906055A priority Critical patent/FR2450835A2/en
Priority to DK149279A priority patent/DK149279A/en
Priority to NO79791222A priority patent/NO791222L/en
Priority to IL57061A priority patent/IL57061A0/en
Priority to IT21793/79A priority patent/IT1111923B/en
Priority to DE19792914805 priority patent/DE2914805A1/en
Priority to FI791194A priority patent/FI791194A/en
Priority to ES479540A priority patent/ES479540A1/en
Priority to GB7912932A priority patent/GB2018751A/en
Priority to PT69487A priority patent/PT69487A/en
Priority to NL7902958A priority patent/NL7902958A/en
Priority to LU81145A priority patent/LU81145A1/en
Priority to GR58869A priority patent/GR66991B/el
Priority to JP4595879A priority patent/JPS54145700A/en
Publication of FR2450835A2 publication Critical patent/FR2450835A2/en
Publication of FR2450835B2 publication Critical patent/FR2450835B2/fr
Application granted granted Critical
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

DERIVES DE BENZODIAZEPINE REPONDANT A LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN RADICAL CYCLOALKYLE DE 4 A 6ATOMES DE CARBONE ET R EST UN ATOME D'HYDROGENE OU D'HALOGENE, AINSI QUE LEURS SELS D'ADDITION AUX ACIDES PHARMACEUTIQUEMENT ACCEPTABLES. APPLICATION EN THERAPEUTIQUE.BENZODIAZEPINE DERIVATIVES RESPONDING TO THE FORMULA: (CF DRAWING IN BOPI) IN WHICH R IS A CYCLOALKYL RADICAL OF 4 TO 6 CARBON ATOMS AND R IS A HYDROGEN OR HALOGEN ATOM, AS WELL AS THEIR SALTS OF ADDITION TO PHARMACEUTICAL ACIDS ACCEPTABLE. APPLICATION IN THERAPEUTICS.

FR7906055A 1978-04-14 1979-03-09 TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION Granted FR2450835A2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR7906055A FR2450835A2 (en) 1978-04-14 1979-03-09 TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
DK149279A DK149279A (en) 1978-04-14 1979-04-10 TETRAHYDROALSTONE INDIVIDUALS AND SALTS THEREOF AND THE PREPARATION OF THEIR PREPARATION
NO79791222A NO791222L (en) 1978-04-14 1979-04-10 PROCEDURE FOR THE PREPARATION OF TETRAHYDROALSTONE INDIVATIVES
IL57061A IL57061A0 (en) 1978-04-14 1979-04-11 Tetrahydroalstonine derivatives their preparation and parmaceutical compositions containing them
IT21793/79A IT1111923B (en) 1978-04-14 1979-04-11 TETRAIIDRAOALSTONINA DERIVATIVES AND THEIR USE IN THERAPEUTIC
DE19792914805 DE2914805A1 (en) 1978-04-14 1979-04-11 TETRAHYDROALSTONE DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM
FI791194A FI791194A (en) 1978-04-14 1979-04-11 TETRAHYDROALSTONE DERIVATIVES
ES479540A ES479540A1 (en) 1978-04-14 1979-04-11 Tetrahydroalstonine derivatives
GB7912932A GB2018751A (en) 1978-04-14 1979-04-12 Tetrahydroalstonine derivatives
PT69487A PT69487A (en) 1978-04-14 1979-04-12 PROCESS FOR THE PREPARATION OF TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
NL7902958A NL7902958A (en) 1978-04-14 1979-04-12 PROCEDURE FOR PREPARING TETRAHYDROALSTONIN DERIVATIVES AND USE AS A THERAPEUTIC AGENT.
LU81145A LU81145A1 (en) 1978-04-14 1979-04-12 TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
GR58869A GR66991B (en) 1978-04-14 1979-04-12
JP4595879A JPS54145700A (en) 1978-04-14 1979-04-13 Tetrahydroarstonine derivative and its manufacture

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7811026A FR2422664A1 (en) 1978-04-14 1978-04-14 Tetra:hydro:alstonine ester and amide derivs. - with anti:anoxic, psychotropic and antidepressant activity (BE 15.10.79)
FR7906055A FR2450835A2 (en) 1978-04-14 1979-03-09 TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
FR2450835A2 true FR2450835A2 (en) 1980-10-03
FR2450835B2 FR2450835B2 (en) 1982-11-19

Family

ID=26220552

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7906055A Granted FR2450835A2 (en) 1978-04-14 1979-03-09 TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION

Country Status (14)

Country Link
JP (1) JPS54145700A (en)
DE (1) DE2914805A1 (en)
DK (1) DK149279A (en)
ES (1) ES479540A1 (en)
FI (1) FI791194A (en)
FR (1) FR2450835A2 (en)
GB (1) GB2018751A (en)
GR (1) GR66991B (en)
IL (1) IL57061A0 (en)
IT (1) IT1111923B (en)
LU (1) LU81145A1 (en)
NL (1) NL7902958A (en)
NO (1) NO791222L (en)
PT (1) PT69487A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2451376B1 (en) * 1979-03-14 1986-04-18 Fabre Sa Pierre NOVEL TETRAHYDROALSTONIC DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
BE881050A (en) * 1980-01-09 1980-07-09 Omnichemue NOVEL OXAYOHIMBANE-TYPE DERIVATIVES, PROCESS FOR OBTAINING SAME AND MEDICAMENTS CONTAINING THEM
FR2539416B1 (en) * 1983-01-14 1985-09-27 Adir NOVEL OXINDOLIC DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SE501156C2 (en) * 1993-04-21 1994-11-28 Ellemtel Utvecklings Ab Reference signal composed of clock signal and synchronization signal, synchronization device and method, etc. reference signal

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1225652B (en) * 1961-08-01 1966-09-29 Boehringer & Soehne Gmbh Process for the preparation of 3, 4, 5, 6-tetrahydroserpentine derivatives substituted in the 1-position and their salts

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1225652B (en) * 1961-08-01 1966-09-29 Boehringer & Soehne Gmbh Process for the preparation of 3, 4, 5, 6-tetrahydroserpentine derivatives substituted in the 1-position and their salts

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1978 *

Also Published As

Publication number Publication date
FI791194A (en) 1979-10-15
JPS54145700A (en) 1979-11-14
IT7921793A0 (en) 1979-04-11
ES479540A1 (en) 1979-07-16
DE2914805A1 (en) 1979-10-18
IL57061A0 (en) 1979-07-25
PT69487A (en) 1979-05-01
LU81145A1 (en) 1980-12-16
NO791222L (en) 1979-10-16
NL7902958A (en) 1979-10-16
DK149279A (en) 1979-10-15
GB2018751A (en) 1979-10-24
IT1111923B (en) 1986-01-13
GR66991B (en) 1981-05-18
FR2450835B2 (en) 1982-11-19

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