ES479540A1 - Tetrahydroalstonine derivatives - Google Patents

Tetrahydroalstonine derivatives

Info

Publication number
ES479540A1
ES479540A1 ES479540A ES479540A ES479540A1 ES 479540 A1 ES479540 A1 ES 479540A1 ES 479540 A ES479540 A ES 479540A ES 479540 A ES479540 A ES 479540A ES 479540 A1 ES479540 A1 ES 479540A1
Authority
ES
Spain
Prior art keywords
radical
alkoxy
dialkylamino
alkyl
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES479540A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7811026A external-priority patent/FR2422664A1/en
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES479540A1 publication Critical patent/ES479540A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

Compounds corresponding to the formula < IMAGE > in which R1 is hydrogen or a hydroxyalkyl, alkyl or alkoxycarbonyl radical and R2 is either a hydroxyl radical, or a linear or branched alkoxy radical which can carry halogens as substituents, or a (cycloalkyl)-alkoxy radical, or a cycloalkoxy radical, or an alkoxy radical carrying a piperidino, morpholino, piperazino or pyrrolidino group, or a (dialkylamino)- alkoxy radical, or an amino radical, or an alkylamino radical, or a dialkylamino radical, or a cycloalkylamino radical or a radical OMe (Me = alkali metal or alkaline earth metal), except for the compound wherein R1 is H and R2 is CH3O, the alkyl and alkoxy radicals having from 1 to 6 carbon atoms and the cyloalkyl and cycloalkoxy radicals having from 3 to 6 carbon atoms, and also their addition salts with pharmaceutically acceptable acids, have anti-anoxia and psychotropic activity and are useful in treating cerebral disorders.
ES479540A 1978-04-14 1979-04-11 Tetrahydroalstonine derivatives Expired ES479540A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7811026A FR2422664A1 (en) 1978-04-14 1978-04-14 Tetra:hydro:alstonine ester and amide derivs. - with anti:anoxic, psychotropic and antidepressant activity (BE 15.10.79)
FR7906055A FR2450835A2 (en) 1978-04-14 1979-03-09 TETRAHYDROALSTONIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION

Publications (1)

Publication Number Publication Date
ES479540A1 true ES479540A1 (en) 1979-07-16

Family

ID=26220552

Family Applications (1)

Application Number Title Priority Date Filing Date
ES479540A Expired ES479540A1 (en) 1978-04-14 1979-04-11 Tetrahydroalstonine derivatives

Country Status (14)

Country Link
JP (1) JPS54145700A (en)
DE (1) DE2914805A1 (en)
DK (1) DK149279A (en)
ES (1) ES479540A1 (en)
FI (1) FI791194A (en)
FR (1) FR2450835A2 (en)
GB (1) GB2018751A (en)
GR (1) GR66991B (en)
IL (1) IL57061A0 (en)
IT (1) IT1111923B (en)
LU (1) LU81145A1 (en)
NL (1) NL7902958A (en)
NO (1) NO791222L (en)
PT (1) PT69487A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2451376B1 (en) * 1979-03-14 1986-04-18 Fabre Sa Pierre NOVEL TETRAHYDROALSTONIC DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
BE881050A (en) * 1980-01-09 1980-07-09 Omnichemue NOVEL OXAYOHIMBANE-TYPE DERIVATIVES, PROCESS FOR OBTAINING SAME AND MEDICAMENTS CONTAINING THEM
FR2539416B1 (en) * 1983-01-14 1985-09-27 Adir NOVEL OXINDOLIC DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SE501156C2 (en) * 1993-04-21 1994-11-28 Ellemtel Utvecklings Ab Reference signal composed of clock signal and synchronization signal, synchronization device and method, etc. reference signal

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1225652B (en) * 1961-08-01 1966-09-29 Boehringer & Soehne Gmbh Process for the preparation of 3, 4, 5, 6-tetrahydroserpentine derivatives substituted in the 1-position and their salts

Also Published As

Publication number Publication date
FI791194A (en) 1979-10-15
JPS54145700A (en) 1979-11-14
FR2450835A2 (en) 1980-10-03
IT7921793A0 (en) 1979-04-11
DE2914805A1 (en) 1979-10-18
IL57061A0 (en) 1979-07-25
PT69487A (en) 1979-05-01
LU81145A1 (en) 1980-12-16
NO791222L (en) 1979-10-16
NL7902958A (en) 1979-10-16
DK149279A (en) 1979-10-15
GB2018751A (en) 1979-10-24
IT1111923B (en) 1986-01-13
GR66991B (en) 1981-05-18
FR2450835B2 (en) 1982-11-19

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