SE7705687L - NEW 17B ESTRES OF OSTRADIOL - Google Patents

NEW 17B ESTRES OF OSTRADIOL

Info

Publication number
SE7705687L
SE7705687L SE7705687A SE7705687A SE7705687L SE 7705687 L SE7705687 L SE 7705687L SE 7705687 A SE7705687 A SE 7705687A SE 7705687 A SE7705687 A SE 7705687A SE 7705687 L SE7705687 L SE 7705687L
Authority
SE
Sweden
Prior art keywords
oestradiol
beta
novel
ostradiol
estres
Prior art date
Application number
SE7705687A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE425789B (en
Inventor
J Van Der Vies
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA762920A external-priority patent/ZA762920B/en
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of SE7705687L publication Critical patent/SE7705687L/en
Publication of SE425789B publication Critical patent/SE425789B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel 17 beta -esters of oestradiol with a branched-chain aliphatic or cycloaliphatic monocarboxylic acid having 8 to 20 carbon atoms are obtained by esterifying oestradiol with the corresponding acid or its functional derivative to give the 3,17 beta -diester and then partially hydrolysing the latter. The novel oestradiol 17 beta -esters possess valuable oestrogenic properties, in particular in association with oral administration in the presence of a lipid.
SE7705687A 1976-05-17 1977-05-16 PROCEDURE FOR THE PREPARATION OF NEW 17BETA ESTERS OF OSTRADIOL SE425789B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA762920A ZA762920B (en) 1975-05-30 1976-05-17 Novel pharmaceutical preparation adapted for oral administration

Publications (2)

Publication Number Publication Date
SE7705687L true SE7705687L (en) 1977-11-18
SE425789B SE425789B (en) 1982-11-08

Family

ID=25570316

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7705687A SE425789B (en) 1976-05-17 1977-05-16 PROCEDURE FOR THE PREPARATION OF NEW 17BETA ESTERS OF OSTRADIOL

Country Status (7)

Country Link
AR (1) AR212996A1 (en)
CH (1) CH630645A5 (en)
DK (1) DK211377A (en)
ES (1) ES458836A1 (en)
FI (1) FI57762C (en)
NL (1) NL7705368A (en)
SE (1) SE425789B (en)

Also Published As

Publication number Publication date
FI57762B (en) 1980-06-30
FI57762C (en) 1980-10-10
DK211377A (en) 1977-11-18
AR212996A1 (en) 1978-11-30
CH630645A5 (en) 1982-06-30
ES458836A1 (en) 1978-03-16
FI771549A (en) 1977-11-18
SE425789B (en) 1982-11-08
NL7705368A (en) 1977-11-21

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