SE7702925L - PROCEDURE FOR PREPARING A POLYPEPTID - Google Patents

PROCEDURE FOR PREPARING A POLYPEPTID

Info

Publication number
SE7702925L
SE7702925L SE7702925A SE7702925A SE7702925L SE 7702925 L SE7702925 L SE 7702925L SE 7702925 A SE7702925 A SE 7702925A SE 7702925 A SE7702925 A SE 7702925A SE 7702925 L SE7702925 L SE 7702925L
Authority
SE
Sweden
Prior art keywords
polypeptid
preparing
procedure
polypeptides
amides
Prior art date
Application number
SE7702925A
Other languages
Unknown language ( )
Swedish (sv)
Inventor
C E Frohman
Original Assignee
Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,851 external-priority patent/US4146614A/en
Application filed by Michigan State filed Critical Michigan State
Publication of SE7702925L publication Critical patent/SE7702925L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PRODUCT AND PROCESS Polypeptides, omega-N-acylated and/or hydrocarbon containing esters or amides of polypeptides are useful in the treatment of schizophrenia. The polypeptide-containing materials have a characteristic T-V-L structure, i.e., , (T) (V) (L) The preferred compositions are N-acytated T-V-L-containing polypeptides, especially amides.
SE7702925A 1976-03-23 1977-03-15 PROCEDURE FOR PREPARING A POLYPEPTID SE7702925L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66952676A 1976-03-23 1976-03-23
US05/772,851 US4146614A (en) 1976-03-23 1977-02-28 Threonyl-valyline leucine containing peptides and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
SE7702925L true SE7702925L (en) 1977-09-24

Family

ID=27100128

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7702925A SE7702925L (en) 1976-03-23 1977-03-15 PROCEDURE FOR PREPARING A POLYPEPTID

Country Status (13)

Country Link
JP (1) JPS52142015A (en)
AU (1) AU510679B2 (en)
CA (1) CA1103239A (en)
DE (1) DE2712781A1 (en)
DK (1) DK125177A (en)
FR (1) FR2351954A1 (en)
GB (1) GB1561247A (en)
GR (1) GR63642B (en)
LU (1) LU76998A1 (en)
NL (1) NL7703124A (en)
NO (1) NO771031L (en)
NZ (1) NZ183627A (en)
SE (1) SE7702925L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ214543A (en) * 1984-12-14 1990-03-27 Australian Commercial Research Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle)
JPH03236315A (en) * 1989-12-05 1991-10-22 Nippon Oil & Fats Co Ltd Antipsychotic agent

Also Published As

Publication number Publication date
AU510679B2 (en) 1980-07-10
CA1103239A (en) 1981-06-16
DE2712781A1 (en) 1977-10-06
GR63642B (en) 1979-11-27
AU2317477A (en) 1978-09-14
NO771031L (en) 1977-09-26
NL7703124A (en) 1977-09-27
FR2351954A1 (en) 1977-12-16
LU76998A1 (en) 1977-10-03
GB1561247A (en) 1980-02-13
DK125177A (en) 1977-09-24
JPS52142015A (en) 1977-11-26
NZ183627A (en) 1980-02-21
FR2351954B1 (en) 1980-03-28

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