SE7700761L - PROCEDURE FOR FIXING PROTEINS ON CARRIERSŸ - Google Patents

PROCEDURE FOR FIXING PROTEINS ON CARRIERSŸ

Info

Publication number
SE7700761L
SE7700761L SE7700761A SE7700761A SE7700761L SE 7700761 L SE7700761 L SE 7700761L SE 7700761 A SE7700761 A SE 7700761A SE 7700761 A SE7700761 A SE 7700761A SE 7700761 L SE7700761 L SE 7700761L
Authority
SE
Sweden
Prior art keywords
protein
reacting
groups
aliphatic
formula
Prior art date
Application number
SE7700761A
Other languages
Swedish (sv)
Inventor
J Horn
H-G Batz
D Jaworek
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of SE7700761L publication Critical patent/SE7700761L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/096—Polyesters; Polyamides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polyamides (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Biologically active proteins are immobilized onto a carrier by reacting a compound containing at least two secondary amino groups at a temperature of from -80 DEG to +50 DEG C with a chlorination agent with the conversion of the secondary amino groups into iminochloride groups of the formula <IMAGE> in which R and R1, which can be the same or different, are aliphatic, aromatic or aliphatic-aromatic radicals, and reacting the carrier material product thus obtained (A) DIRECTLY WITH A BIOLOGICALLY-ACTIVE PROTEIN, IN AN AQUEOUS SOLVENT, OR (B) WITH A BIFUNCTIONAL COMPOUND CONTAINING AT LEAST ONE PRIMARY AMINO GROUP, OPTIONALLY IN AN AQUEOUS OR ORGANIC SOLVENT, AND REACTING THE PRODUCT THEREBY OBTAINED CONTAINING GROUPS OF THE FORMULA <IMAGE> in which R2 is an alkylene radical, an alpha , omega -dioxyalkylene radical or a dicarboxylic acid amide group containing 2 to 8 carbon atoms and X is a primary amino group or a function capable of protein binding either (I) DIRECTLY WITH A PROTEIN OR (II) FIRST WITH AT LEAST ONE BIFUNCTIONAL OR POLYFUNCTIONAL PROTEIN REAGENT AND THEREAFTER WITH A PROTEIN OR WITH A REACTION PRODUCT OF A PROTEIN WITH THE PROTEIN REAGENT.
SE7700761A 1976-01-29 1977-01-25 PROCEDURE FOR FIXING PROTEINS ON CARRIERSŸ SE7700761L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2603319A DE2603319C3 (en) 1976-01-29 1976-01-29 Method for the fixation of biologically active proteins on carriers

Publications (1)

Publication Number Publication Date
SE7700761L true SE7700761L (en) 1977-07-30

Family

ID=5968538

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7700761A SE7700761L (en) 1976-01-29 1977-01-25 PROCEDURE FOR FIXING PROTEINS ON CARRIERSŸ

Country Status (17)

Country Link
US (1) US4119589A (en)
JP (1) JPS5294489A (en)
AT (1) AT359021B (en)
AU (1) AU509729B2 (en)
BE (1) BE850717A (en)
CA (1) CA1087608A (en)
CH (1) CH626092A5 (en)
DD (1) DD128404A5 (en)
DE (1) DE2603319C3 (en)
DK (1) DK36377A (en)
FR (1) FR2339620A1 (en)
GB (1) GB1521243A (en)
HU (1) HU176482B (en)
IL (1) IL51126A (en)
IT (1) IT1065504B (en)
NL (1) NL7614014A (en)
SE (1) SE7700761L (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528806A (en) * 1945-11-09 1950-11-07 Deere & Co Beet harvester
DE2708018A1 (en) * 1977-02-24 1978-09-07 Boehringer Mannheim Gmbh BIOLOGICALLY ACTIVE PROTEIN FIXED TO POLYAMIDE AND THE PROCESS FOR ITS PRODUCTION
US4415490A (en) * 1979-07-24 1983-11-15 Nippon Zeon Co., Ltd. Non-thrombogenic material
US4279787A (en) * 1979-07-30 1981-07-21 Tetra Consultants Inc. Method of binding antigens to insoluble polymeric substances
WO1981001145A1 (en) * 1979-10-18 1981-04-30 Univ Illinois Hydrolytic enzyme-activatible pro-drugs
JPS5670028A (en) * 1979-11-12 1981-06-11 Teijin Ltd Polymer bonding with albumin
AR231590A1 (en) * 1981-04-29 1984-12-28 Ciba Geigy Ag IMMUNOLOGICAL ANALYSIS DEVICE AND PROCEDURE TO OBTAIN IT
IL66094A0 (en) * 1982-06-22 1982-09-30 Yeda Res & Dev Synthesis with multipolymer systems
US4595656A (en) * 1984-01-06 1986-06-17 Becton Dickinson & Company Coupling agents and products produced therefrom
US4615985A (en) * 1984-04-16 1986-10-07 Genetic Diagnostics Corporation Immobilized protein on nylon for immunoassay
AU583060B2 (en) * 1984-10-29 1989-04-20 Memtec Limited Sulphuryl chloride/polyamide derivatives
US5108923A (en) * 1986-04-25 1992-04-28 Collaborative Research, Inc. Bioadhesives for cell and tissue adhesion
US4952519A (en) * 1988-05-02 1990-08-28 E. I. Du Pont De Nemours And Company Protein immobilization with poly(ethyleneimine) derivatized with a hydroprobic group
ATE102074T1 (en) * 1989-09-29 1994-03-15 Rohm & Haas LIGAND-CONTAINING MEDIUM FOR CHROMATOGRAPHIC SEPARATION, PROCESS FOR ITS PREPARATION AND ITS USE FOR ISOLATION OF SYNTHETIC OR NATURAL MOLECULES FROM A FLUID MIXTURE.
CA2073511A1 (en) * 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5424219A (en) * 1991-10-25 1995-06-13 Cytech Biomedical, Inc. Method of performing assays for biomolecules and solid supports for use in such methods
EP0943094A2 (en) * 1996-12-05 1999-09-22 Idego ApS Sensor laminates and multi-sectioned fluid delivery devices for detecting by immunoassay target molecules in biological fluids
WO2016182870A1 (en) 2015-05-08 2016-11-17 Under Armour, Inc. Footwear including a textile upper

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1171774A (en) * 1966-02-10 1969-11-26 Dunlop Co Ltd Improvements in and relating to Bonding.
US3639558A (en) * 1968-02-19 1972-02-01 Louis Csizmas Immunological reagent particles having proteinaceous materials covalently bonded thereto
AT317424B (en) * 1971-06-09 1974-08-26 Boehringer Mannheim Gmbh Process for the production of carrier-bound proteins
US3830699A (en) * 1972-03-16 1974-08-20 Exxon Research Engineering Co Insolubilized enzymes
IL42516A (en) * 1973-06-15 1976-11-30 Mordechai Sokolovsky Polyamides substituted with aldehyde and isonitrile residues and process for the production of same
FR2234311B1 (en) * 1973-06-21 1976-04-30 Air Liquide
GB1485122A (en) * 1973-08-06 1977-09-08 Nat Res Dev Biologically active matrices
US3985617A (en) * 1974-10-29 1976-10-12 Ajinomoto Co., Inc. Immobilization of biologically active proteins with a polypeptide azide
US4007089A (en) * 1975-04-30 1977-02-08 Nelson Research & Development Company Method for binding biologically active compounds
US4045384A (en) * 1976-07-23 1977-08-30 The Dow Chemical Company Method for forming an amide bond between a latex and protein

Also Published As

Publication number Publication date
IL51126A0 (en) 1977-02-28
FR2339620B1 (en) 1981-07-24
DE2603319C3 (en) 1979-08-23
IT1065504B (en) 1985-02-25
CA1087608A (en) 1980-10-14
AT359021B (en) 1980-10-10
DE2603319B2 (en) 1978-12-21
ATA872676A (en) 1980-03-15
DD128404A5 (en) 1977-11-16
BE850717A (en) 1977-07-25
AU509729B2 (en) 1980-05-22
FR2339620A1 (en) 1977-08-26
DE2603319A1 (en) 1977-08-11
DK36377A (en) 1977-07-30
US4119589A (en) 1978-10-10
HU176482B (en) 1981-03-28
AU2173777A (en) 1978-08-03
GB1521243A (en) 1978-08-16
JPS5294489A (en) 1977-08-09
CH626092A5 (en) 1981-10-30
IL51126A (en) 1979-11-30
NL7614014A (en) 1977-08-02

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