SE7602349L - PROSTAGLAND INDIVIDUALS - Google Patents
PROSTAGLAND INDIVIDUALSInfo
- Publication number
- SE7602349L SE7602349L SE7602349A SE7602349A SE7602349L SE 7602349 L SE7602349 L SE 7602349L SE 7602349 A SE7602349 A SE 7602349A SE 7602349 A SE7602349 A SE 7602349A SE 7602349 L SE7602349 L SE 7602349L
- Authority
- SE
- Sweden
- Prior art keywords
- prostagland
- individuals
- hydroxylactones
- trialkylborohydride
- prostaglandins
- Prior art date
Links
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Bicyclic alpha -hydroxylactones of the formula <IMAGE> in which the substituents are defined in Claim 1, are prepared by a stereoselective process. In this process, the lateral oxo group of corresponding lactones is reduced using a potassium trialkylborohydride. The resulting compounds can be used as intermediates in the preparation of prostaglandins.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56596275A | 1975-04-07 | 1975-04-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7602349L true SE7602349L (en) | 1976-10-08 |
| SE424866B SE424866B (en) | 1982-08-16 |
Family
ID=24260841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7602349A SE424866B (en) | 1975-04-07 | 1976-02-25 | PROCEDURE FOR STEREOSELECTIVE REDUCTION OF SIDO CHAIN OXOGRUP TO A 15 ALFA HYDROXY GROUP IN A BICYCLIC LAKTON |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS6028835B2 (en) |
| BE (1) | BE840477A (en) |
| CA (1) | CA1069520A (en) |
| CH (1) | CH621548A5 (en) |
| DE (1) | DE2613306A1 (en) |
| DK (1) | DK163076A (en) |
| FR (1) | FR2306985A1 (en) |
| GB (1) | GB1498764A (en) |
| HU (1) | HU174651B (en) |
| MX (1) | MX3325E (en) |
| NL (1) | NL7603568A (en) |
| PL (1) | PL104354B1 (en) |
| SE (1) | SE424866B (en) |
| ZA (1) | ZA761506B (en) |
-
1976
- 1976-02-25 SE SE7602349A patent/SE424866B/en not_active IP Right Cessation
- 1976-03-03 MX MX000033U patent/MX3325E/en unknown
- 1976-03-05 CA CA247,329A patent/CA1069520A/en not_active Expired
- 1976-03-10 GB GB9505/76A patent/GB1498764A/en not_active Expired
- 1976-03-11 ZA ZA761506A patent/ZA761506B/en unknown
- 1976-03-22 CH CH355576A patent/CH621548A5/en not_active IP Right Cessation
- 1976-03-23 JP JP51030920A patent/JPS6028835B2/en not_active Expired
- 1976-03-29 DE DE19762613306 patent/DE2613306A1/en active Granted
- 1976-04-06 FR FR7609952A patent/FR2306985A1/en active Granted
- 1976-04-06 HU HU76UO117A patent/HU174651B/en not_active IP Right Cessation
- 1976-04-06 NL NL7603568A patent/NL7603568A/en not_active Application Discontinuation
- 1976-04-06 DK DK163076A patent/DK163076A/en not_active IP Right Cessation
- 1976-04-07 PL PL1976188562A patent/PL104354B1/en unknown
- 1976-04-07 BE BE165923A patent/BE840477A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK163076A (en) | 1976-10-08 |
| HU174651B (en) | 1980-02-28 |
| SE424866B (en) | 1982-08-16 |
| PL104354B1 (en) | 1979-08-31 |
| JPS6028835B2 (en) | 1985-07-06 |
| DE2613306C2 (en) | 1987-08-13 |
| BE840477A (en) | 1976-10-07 |
| GB1498764A (en) | 1978-01-25 |
| AU1198676A (en) | 1977-09-22 |
| JPS51118758A (en) | 1976-10-18 |
| FR2306985A1 (en) | 1976-11-05 |
| NL7603568A (en) | 1976-10-11 |
| FR2306985B1 (en) | 1980-01-25 |
| CH621548A5 (en) | 1981-02-13 |
| ZA761506B (en) | 1977-03-30 |
| MX3325E (en) | 1980-09-26 |
| CA1069520A (en) | 1980-01-08 |
| DE2613306A1 (en) | 1976-10-21 |
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