SE7600232L - IMMUNOLOGICAL REAGENTS AND WAY TO USE THE SAME - Google Patents

IMMUNOLOGICAL REAGENTS AND WAY TO USE THE SAME

Info

Publication number
SE7600232L
SE7600232L SE7600232A SE7600232A SE7600232L SE 7600232 L SE7600232 L SE 7600232L SE 7600232 A SE7600232 A SE 7600232A SE 7600232 A SE7600232 A SE 7600232A SE 7600232 L SE7600232 L SE 7600232L
Authority
SE
Sweden
Prior art keywords
insolubilization
antigen
antibody complex
way
same
Prior art date
Application number
SE7600232A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE441392B (en
Inventor
C Deaton
E Achter
J Kremen
R Rodriguez
P Priarone
Original Assignee
Baxter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/615,024 external-priority patent/US4148869A/en
Application filed by Baxter Laboratories Inc filed Critical Baxter Laboratories Inc
Publication of SE7600232L publication Critical patent/SE7600232L/en
Publication of SE441392B publication Critical patent/SE441392B/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Immunological assaying methods which require insolubilization of an antigen-antibody complex as an integral step thereof are improved by adding to the test medium in which insolubilization is desired an aqueous reagent solution containing from about 3 to 6% by weight of a mixture of polyethylene glycol and a nonionic surfactant, and which solution has a calculated HLB (Hydrophilic-Lipophilic-Balance) of about 0.7 to 1.7. This solution increases the insolubilization of the antigen-antibody complex with reduced incubation times, and produces an assay procedure of greater test range and sensitivity. A preferred embodiment involves usage in a nephelometric analysis.
SE7600232A 1975-01-29 1976-01-12 PROCEDURE AND REAGENTS IN IMMUNOLOGICAL ANALYSIS LIKE LIGHT DISTRIBUTION SEATING AS APPLICABLE TO REAGENTS IN SUCH ANALYSIS SE441392B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54506675A 1975-01-29 1975-01-29
US55590875A 1975-03-06 1975-03-06
US05/615,024 US4148869A (en) 1975-03-06 1975-09-19 Immunological reagent and method of using same

Publications (2)

Publication Number Publication Date
SE7600232L true SE7600232L (en) 1976-07-30
SE441392B SE441392B (en) 1985-09-30

Family

ID=27415448

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7600232A SE441392B (en) 1975-01-29 1976-01-12 PROCEDURE AND REAGENTS IN IMMUNOLOGICAL ANALYSIS LIKE LIGHT DISTRIBUTION SEATING AS APPLICABLE TO REAGENTS IN SUCH ANALYSIS

Country Status (15)

Country Link
JP (1) JPS604938B2 (en)
BE (1) BE837675A (en)
BR (1) BR7600322A (en)
CA (1) CA1080619A (en)
CH (1) CH613047A5 (en)
DE (2) DE2661010C2 (en)
DK (1) DK150809C (en)
ES (1) ES444543A1 (en)
FR (1) FR2299645A1 (en)
GB (1) GB1540097A (en)
IL (1) IL48804A (en)
IT (1) IT1062433B (en)
NL (1) NL183852C (en)
NO (1) NO149864C (en)
SE (1) SE441392B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901327B1 (en) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Method for determining an opsonizing surface-binding alpha-glycoprotein
FI792576A (en) * 1979-08-20 1981-02-21 Orion Yhtymae Oy METHOD OF ENZYME IMMUNOLOGICAL ASSESSMENT
JPS5943362A (en) * 1982-09-06 1984-03-10 Kainosu:Kk Immunological measuring reagent
AU580248B2 (en) * 1982-10-13 1989-01-12 Biowhittaker Technologies, Inc. Fluorometric assay of allergic reactions and reagents therefor
GB8317855D0 (en) * 1983-06-30 1983-08-03 Iq Bio Ltd Biochemical detection method
DE3327642A1 (en) * 1983-07-30 1985-02-14 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD FOR DETERMINING A PARTNER OF AN IMMUNE REACTION AND REAGENT FOR CARRYING OUT THIS METHOD
DE3532626A1 (en) * 1985-09-12 1987-03-19 Boehringer Mannheim Gmbh METHOD FOR DETERMINING A PARTNER OF AN IMMUNE REACTION
JPS62159047A (en) * 1985-12-31 1987-07-15 Chemo Sero Therapeut Res Inst Reagent for quantitative determination of plasma protein
US4810638A (en) * 1986-07-24 1989-03-07 Miles Inc. Enzyme-labeled antibody reagent with polyalkyleneglycol linking group
JP2684069B2 (en) * 1988-10-13 1997-12-03 昇一 首藤 Method for measuring immunologically active substance and reagent therefor
CA2077906A1 (en) * 1991-01-10 1992-07-11 Kimihiko Matsuzawa Method for measurement of tissue factor in high sensitivity and measurement kit therefor
AU6525494A (en) * 1993-03-26 1994-10-24 Curative Technologies, Inc. Method and assay involving improved specific binding reactivity of a polypeptide
EP1617277B1 (en) * 2003-04-03 2009-05-27 Seed Co., Ltd. Ophthalmic lenses capable of sustained drug release and preservative solutions therefor
JP4915638B2 (en) * 2005-08-26 2012-04-11 パナソニック株式会社 Electrodeless discharge lamp device and lighting fixture equipped with the electrodeless discharge lamp device
JP6242068B2 (en) * 2013-04-10 2017-12-06 積水メディカル株式会社 Latex immunoagglutination measurement reagent
KR20210089710A (en) * 2018-11-09 2021-07-16 세키스이 메디칼 가부시키가이샤 Method for suppressing abnormal detection in immunoassay in automatic analysis device, and immunoassay reagent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1598151A1 (en) * 1966-11-19 1970-05-27 Kleine Dr Rer Nat Norbert Agglutination enhancers
DE2361169C3 (en) * 1973-12-07 1978-09-14 Boehringer Mannheim Gmbh, 6800 Mannheim Process for the activation of cholesterol oxidase freed from detergent traces
US3947250A (en) * 1974-06-21 1976-03-30 Baxter Laboratories, Inc. Method of immunodiffusion

Also Published As

Publication number Publication date
GB1540097A (en) 1979-02-07
BE837675A (en) 1976-07-19
FR2299645A1 (en) 1976-08-27
JPS604938B2 (en) 1985-02-07
NO149864C (en) 1984-07-04
NO760203L (en) 1976-07-30
DK150809B (en) 1987-06-22
JPS51101121A (en) 1976-09-07
IL48804A (en) 1979-05-31
NL7600697A (en) 1976-08-02
NL183852B (en) 1988-09-01
ES444543A1 (en) 1977-06-01
BR7600322A (en) 1976-08-31
SE441392B (en) 1985-09-30
NO149864B (en) 1984-03-26
NL183852C (en) 1989-02-01
DE2602068A1 (en) 1976-08-05
CH613047A5 (en) 1979-08-31
IT1062433B (en) 1984-10-10
DK150809C (en) 1988-05-02
DK16976A (en) 1976-07-30
DE2602068C2 (en) 1986-09-11
CA1080619A (en) 1980-07-01
FR2299645B1 (en) 1980-11-28
DE2661010C2 (en) 1987-03-19
IL48804A0 (en) 1976-03-31

Similar Documents

Publication Publication Date Title
SE7600232L (en) IMMUNOLOGICAL REAGENTS AND WAY TO USE THE SAME
ATE67858T1 (en) IMMUNOLOGICAL TEST PROCEDURE.
IE790802L (en) Cytological assay
SE8000427L (en) MAGNETIC GEL FOR IMMUNOENZYMATIC ANALYSIS
GB1436934A (en) Method of testing blood
SE8102558L (en) IMMUNOLOGICAL DETERMINATION METHOD
DK155052C (en) REAGENT, TEST MATERIAL AND PROCEDURE FOR DETECTING THE PRESENCE AND / OR DETERMINING THE CONCENTRATION OF GLUCOSE IN A TEST SAMPLE
KR830010384A (en) Method for measuring antigen antibody response and its reagent
ES8106209A1 (en) carrier particles and diagnostic reagent produced thereby and test kit containing such reagents.
SE7706338L (en) KIT AND DEVICE FOR ANALYSIS
ES511156A0 (en) A METHOD OF DETERMINING THE PRESENCE OF AN ANTIGEN IN A LIQUID MEDIUM SUSPECTED TO CONTAIN IT.
ATE17048T1 (en) IMMUNOASSAY.
ATE67315T1 (en) PROCEDURE FOR PERFORMING IMMUNOFLUORESCENCE TESTING.
JPS5294418A (en) Diluent for measuring rubella hi antibody
DK83885A (en) TEST MATERIAL FOR DETERMINING THE PRESENCE OF AN ION IN AN AQUE TEST SAMPLE AND MATERIAL PREPARATION
KR850001699A (en) Method for preparing a reagent for detecting adult T cell leukemia virus
KR850008620A (en) Methods and reagents for measuring ATL virus antibodies
ES2076221T3 (en) GEMINAL DERIVATIVES OF DIFENYL AND ITS USE IN IMMUNO ASSAYS.
EP0204579A3 (en) Immunoassay incubation device
ES2056132T3 (en) IMMUNOCHEMICAL TEST AGENT CONTAINING AMINE OXIDES.
ES2016992B3 (en) REAGENT AND PROCEDURE IN DETERMINATION C 3A THROUGH IMMUNOCHEMICAL TEST.
JPS562556A (en) Aqueous solvent for coagulating test
ATE91024T1 (en) SOLID PHASE IMMUNOASSAY PROCEDURE.
KR870007685A (en) Reagents for detecting virus antibodies
JPS5334917A (en) Quantitative determination of antigen and antibody

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7600232-8

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7600232-8

Format of ref document f/p: F