SE7506695L - Forfarande for framstellning av insulin, insulin-analoger och -derivat. - Google Patents
Forfarande for framstellning av insulin, insulin-analoger och -derivat.Info
- Publication number
- SE7506695L SE7506695L SE7506695A SE7506695A SE7506695L SE 7506695 L SE7506695 L SE 7506695L SE 7506695 A SE7506695 A SE 7506695A SE 7506695 A SE7506695 A SE 7506695A SE 7506695 L SE7506695 L SE 7506695L
- Authority
- SE
- Sweden
- Prior art keywords
- insulin
- derivatives
- procedure
- preparing
- analogs
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
- 102000004877 Insulin Human genes 0.000 title abstract 3
- 108090001061 Insulin Proteins 0.000 title abstract 3
- 229940125396 insulin Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 abstract 1
- -1 insulin compound Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19742428412 DE2428412A1 (de) | 1974-06-12 | 1974-06-12 | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7506695L true SE7506695L (sv) | 1975-12-15 |
Family
ID=5917967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7506695A SE7506695L (sv) | 1974-06-12 | 1975-06-11 | Forfarande for framstellning av insulin, insulin-analoger och -derivat. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4014861A (sv) |
| JP (1) | JPS5811427B2 (sv) |
| AU (1) | AU8203875A (sv) |
| BE (1) | BE830186A (sv) |
| CA (1) | CA1044227A (sv) |
| CH (1) | CH613185A5 (sv) |
| DE (1) | DE2428412A1 (sv) |
| DK (1) | DK263175A (sv) |
| FR (1) | FR2274605A1 (sv) |
| GB (1) | GB1516515A (sv) |
| IL (1) | IL47443A (sv) |
| LU (1) | LU72693A1 (sv) |
| NL (1) | NL7506754A (sv) |
| SE (1) | SE7506695L (sv) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3327928A1 (de) * | 1983-08-03 | 1985-02-21 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von insulin-derivaten |
| DE3501641A1 (de) * | 1985-01-19 | 1986-07-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen |
| US4885163A (en) * | 1987-02-24 | 1989-12-05 | Eli Lilly And Company | Topical use of IGF-II for wound healing |
| US5106762A (en) * | 1990-04-20 | 1992-04-21 | Georgetown University | Ligand-label conjugates which contain polyoxoanions of sulfur or phosphorus |
| JPH04102934U (ja) * | 1991-02-08 | 1992-09-04 | 株式会社タマハシ | しやくし置き付き調理鍋 |
| FR2707992B1 (fr) * | 1993-07-21 | 1995-10-13 | Flamel Tech Sa | Nouveaux produits organiques contenant des fonctions thiols réactives, l'un de leurs procédés de préparation et les biomatériaux les contenant. |
| US6001604A (en) * | 1993-12-29 | 1999-12-14 | Bio-Technology General Corp. | Refolding of proinsulins without addition of reducing agents |
| US5646242A (en) | 1994-11-17 | 1997-07-08 | Eli Lilly And Company | Selective acylation of epsilon-amino groups |
| US5700904A (en) * | 1995-06-07 | 1997-12-23 | Eli Lilly And Company | Preparation of an acylated protein powder |
| US5631347A (en) * | 1995-06-07 | 1997-05-20 | Eli Lilly And Company | Reducing gelation of a fatty acid-acylated protein |
| WO2011031662A1 (en) | 2009-09-08 | 2011-03-17 | Kent Stephen B H | Ester insulin |
| CN111204777B (zh) * | 2020-01-17 | 2021-05-07 | 中国航空工业集团公司济南特种结构研究所 | 一种溴化氰工业化纯化工艺及设备 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907763A (en) * | 1972-03-01 | 1975-09-23 | Bayer Ag | Insulin derivatives crosslinked by a dicarboxylic acid moiety |
| DE2252157C3 (de) * | 1972-10-25 | 1976-03-18 | Hoechst Ag | Zwischenprodukte zur herstellung von insulin, insulin-analogen und -derivaten und verfahren zur herstellung von insulin, insulin analogen und derivaten |
| DE2253327A1 (de) * | 1972-10-31 | 1974-05-09 | Hoechst Ag | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
| NL7314766A (sv) * | 1972-10-31 | 1974-05-02 |
-
1974
- 1974-06-12 DE DE19742428412 patent/DE2428412A1/de not_active Withdrawn
-
1975
- 1975-06-06 NL NL7506754A patent/NL7506754A/xx unknown
- 1975-06-09 CH CH741675A patent/CH613185A5/xx not_active IP Right Cessation
- 1975-06-09 IL IL47443A patent/IL47443A/xx unknown
- 1975-06-10 US US05/585,604 patent/US4014861A/en not_active Expired - Lifetime
- 1975-06-10 LU LU72693A patent/LU72693A1/xx unknown
- 1975-06-10 CA CA229,026A patent/CA1044227A/en not_active Expired
- 1975-06-11 AU AU82038/75A patent/AU8203875A/en not_active Expired
- 1975-06-11 SE SE7506695A patent/SE7506695L/sv not_active Application Discontinuation
- 1975-06-11 DK DK263175A patent/DK263175A/da unknown
- 1975-06-12 GB GB25248/75A patent/GB1516515A/en not_active Expired
- 1975-06-12 BE BE157293A patent/BE830186A/xx unknown
- 1975-06-12 JP JP50073026A patent/JPS5811427B2/ja not_active Expired
- 1975-06-12 FR FR7518372A patent/FR2274605A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2428412A1 (de) | 1976-01-15 |
| US4014861A (en) | 1977-03-29 |
| IL47443A0 (en) | 1975-08-31 |
| AU8203875A (en) | 1976-12-16 |
| LU72693A1 (sv) | 1977-03-04 |
| JPS5811427B2 (ja) | 1983-03-02 |
| NL7506754A (nl) | 1975-12-16 |
| JPS5123290A (en) | 1976-02-24 |
| FR2274605A1 (fr) | 1976-01-09 |
| FR2274605B3 (sv) | 1978-02-03 |
| DK263175A (da) | 1975-12-13 |
| CA1044227A (en) | 1978-12-12 |
| CH613185A5 (sv) | 1979-09-14 |
| IL47443A (en) | 1978-04-30 |
| BE830186A (fr) | 1975-12-12 |
| GB1516515A (en) | 1978-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7506695-1 Effective date: 19770314 |