SE7412044L - - Google Patents

Info

Publication number
SE7412044L
SE7412044L SE7412044A SE7412044A SE7412044L SE 7412044 L SE7412044 L SE 7412044L SE 7412044 A SE7412044 A SE 7412044A SE 7412044 A SE7412044 A SE 7412044A SE 7412044 L SE7412044 L SE 7412044L
Authority
SE
Sweden
Prior art keywords
water
active material
glibenclamide
precipitating
produced
Prior art date
Application number
SE7412044A
Other versions
SE402210B (en
Inventor
W Rothe
H Heinamann
F H Schmidt
G Betzien
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of SE7412044L publication Critical patent/SE7412044L/xx
Publication of SE402210B publication Critical patent/SE402210B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Rapidly resorbable particulate glibenclamide having a particle surface area of active material of at least 3 m2/g is produced by precipitating the active material from its solution in an organic solvent or in water or aqueous alcohol, preferably rendered alkaline, using water which is preferably acidified.
SE7412044A 1973-09-26 1974-09-25 PROCEDURE FOR PREPARING A HOG-EFFICIENT, QUICK RESORBABLE PREPARATION OF N-4- (2- (5-CHLORO-2-METHOXYBENZAMIDO) -ETHYL) -PHENYL SULPHONYL-N'-CYCLOHEXYL URBAN SE402210B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2348334A DE2348334C2 (en) 1973-09-26 1973-09-26 New form of preparation of N-4- [2- (5-chloro-2-methoxybenzamido) ethyl] -phenyl-sulfonyl-N'-cyclohexylurea

Publications (2)

Publication Number Publication Date
SE7412044L true SE7412044L (en) 1975-03-27
SE402210B SE402210B (en) 1978-06-26

Family

ID=5893666

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7412044A SE402210B (en) 1973-09-26 1974-09-25 PROCEDURE FOR PREPARING A HOG-EFFICIENT, QUICK RESORBABLE PREPARATION OF N-4- (2- (5-CHLORO-2-METHOXYBENZAMIDO) -ETHYL) -PHENYL SULPHONYL-N'-CYCLOHEXYL URBAN

Country Status (12)

Country Link
US (1) US3979520A (en)
JP (1) JPS5632967B2 (en)
AT (1) AT330954B (en)
BE (1) BE820254A (en)
CA (1) CA1029661A (en)
DE (1) DE2348334C2 (en)
FI (1) FI58068C (en)
FR (1) FR2244455B1 (en)
GB (1) GB1420907A (en)
NL (1) NL174222C (en)
SE (1) SE402210B (en)
ZA (1) ZA745967B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033919A1 (en) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen SOLID PHARMACEUTICAL PREPARATIONS CONTAINING NIFEDIPINE AND METHOD FOR THE PRODUCTION THEREOF
DE3326167A1 (en) * 1983-07-20 1985-02-21 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Solid drug forms which contain as active ingredient N-4-[2- (5-chloro-2-methoxybenzamido)ethyl]phenylsulphonyl-N'-cyclohexylurea, and process for the production thereof
CA1282405C (en) * 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
US4916163A (en) * 1985-06-04 1990-04-10 The Upjohn Company Spray-dried lactose formulation of micronized glyburide
DE3833439A1 (en) * 1988-10-01 1991-09-12 Hoechst Ag METHOD FOR MICRONIZING GLIBENCLAMIDE
SE464743B (en) * 1989-06-21 1991-06-10 Ytkemiska Inst PROCEDURE FOR PREPARATION OF MEDICINAL PARTICLES
US5258185A (en) * 1989-08-23 1993-11-02 Bauer Kurt H Highly active, rapidly absorbable formulations of glibenclamide, processes for the production thereof and their use
AU701042B2 (en) * 1995-02-28 1999-01-21 Aventisub Llc Pharmaceutical composition for piperidinoalkanol compounds
EE04294B1 (en) * 1997-08-26 2004-06-15 Hoechst Marion Roussel, Inc. A pharmaceutical composition for combining piperidinoalkanol decongestant
EP0974356B1 (en) 1998-07-15 2003-09-24 Merck Sante Tablets comprising a combination of metformin and glibenclamide
US6586438B2 (en) * 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US20010036479A1 (en) * 2000-01-14 2001-11-01 Gillian Cave Glyburide composition
WO2006109175A2 (en) * 2005-04-11 2006-10-19 Aurobindo Pharma Limited Solid dosage form of an antidiabetic drug
CN104098489A (en) * 2014-07-10 2014-10-15 沈阳药科大学 Micronized glibenclamide and composition thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB694280A (en) * 1950-09-19 1953-07-15 Merck & Co Inc A stable, non-caking suspension of cortisone acetate in an isotonic aqueous vehicle and the process of preparing said composition
US3008873A (en) * 1957-02-07 1961-11-14 Merck & Co Inc Controlled particle size of 4, 4-dinitrocarbanilide
GB1030395A (en) * 1962-12-26 1966-05-25 Upjohn Co Hypoglycemic sulphonyl urea medicaments
US3401221A (en) * 1964-08-25 1968-09-10 Norwich Pharma Co Treatment of urinary tract infection
US3454635A (en) * 1965-07-27 1969-07-08 Hoechst Ag Benzenesulfonyl-ureas and process for their manufacture
DE2017495A1 (en) * 1970-04-11 1971-11-04 Merck Patent Gmbh, 6100 Darmstadt Sulphonamides embedded in galactomannans
JPS4932056B1 (en) * 1970-12-22 1974-08-27

Also Published As

Publication number Publication date
BE820254A (en) 1975-03-24
AU7365374A (en) 1976-04-01
JPS5632967B2 (en) 1981-07-31
CA1029661A (en) 1978-04-18
FI58068B (en) 1980-08-29
FR2244455A1 (en) 1975-04-18
AT330954B (en) 1976-07-26
SE402210B (en) 1978-06-26
JPS5058216A (en) 1975-05-21
ATA762374A (en) 1975-10-15
DE2348334C2 (en) 1982-11-11
FR2244455B1 (en) 1978-07-21
FI58068C (en) 1980-12-10
FI275574A (en) 1975-03-27
NL7412393A (en) 1975-04-01
NL174222C (en) 1984-05-16
US3979520A (en) 1976-09-07
DE2348334A1 (en) 1975-03-27
ZA745967B (en) 1975-11-26
GB1420907A (en) 1976-01-14
NL174222B (en) 1983-12-16

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