SE448236B - Cykliska dubbla hemiacetaler av endiolforeningar, forfarande for framstellning derav samt cytostatiska, analgetiska och/eller hypotensiva kompositioner, vilka som aktiv komponent innehaller nemnda foreningar - Google Patents

Cykliska dubbla hemiacetaler av endiolforeningar, forfarande for framstellning derav samt cytostatiska, analgetiska och/eller hypotensiva kompositioner, vilka som aktiv komponent innehaller nemnda foreningar

Info

Publication number
SE448236B
SE448236B SE8002549A SE8002549A SE448236B SE 448236 B SE448236 B SE 448236B SE 8002549 A SE8002549 A SE 8002549A SE 8002549 A SE8002549 A SE 8002549A SE 448236 B SE448236 B SE 448236B
Authority
SE
Sweden
Prior art keywords
ascorbic acid
methylglyoxal
compound
endiol
cytostatic
Prior art date
Application number
SE8002549A
Other languages
English (en)
Swedish (sv)
Other versions
SE8002549L (sv
Inventor
G B Fodor
A Szent-Gyorgyi
Original Assignee
Cancer Res Nat Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Nat Found filed Critical Cancer Res Nat Found
Publication of SE8002549L publication Critical patent/SE8002549L/xx
Publication of SE448236B publication Critical patent/SE448236B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/121,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE8002549A 1979-04-06 1980-04-02 Cykliska dubbla hemiacetaler av endiolforeningar, forfarande for framstellning derav samt cytostatiska, analgetiska och/eller hypotensiva kompositioner, vilka som aktiv komponent innehaller nemnda foreningar SE448236B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/027,692 US4238500A (en) 1979-04-06 1979-04-06 Cyclic double hemiacetals of enediol compounds and compositions and methods for preparing and using same

Publications (2)

Publication Number Publication Date
SE8002549L SE8002549L (sv) 1980-10-07
SE448236B true SE448236B (sv) 1987-02-02

Family

ID=21839228

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8002549A SE448236B (sv) 1979-04-06 1980-04-02 Cykliska dubbla hemiacetaler av endiolforeningar, forfarande for framstellning derav samt cytostatiska, analgetiska och/eller hypotensiva kompositioner, vilka som aktiv komponent innehaller nemnda foreningar

Country Status (15)

Country Link
US (1) US4238500A (hu)
JP (1) JPS5649375A (hu)
AU (1) AU521764B2 (hu)
CA (1) CA1167859A (hu)
CH (1) CH643550A5 (hu)
DE (1) DE3010947C2 (hu)
DK (1) DK150780A (hu)
FR (1) FR2453171A1 (hu)
GB (1) GB2061259B (hu)
HU (1) HU182119B (hu)
IE (1) IE49434B1 (hu)
IT (1) IT1141269B (hu)
NL (1) NL8001603A (hu)
NO (1) NO151621C (hu)
SE (1) SE448236B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518611A (en) * 1983-04-04 1985-05-21 National Foundation For Cancer Research, Inc. 2-Furylbutyrolactone modulation of the immune system in mammals
WO1987006585A1 (en) * 1986-04-29 1987-11-05 American Biotechnology Co. Ltd. PRODUCTION AND USE OF REACTION PRODUCT OBTAINED FROM ASCORBIC ACID WITH alpha,beta-UNSATURATED ALICYCLIC KETONE OR VINYL ALIPHATIC KETONE
DE3826303A1 (de) * 1988-08-03 1990-02-08 Basf Ag Verfahren zur herstellung cyclischer 6- bis 8-gliedriger vinylen-1,2-dioxyverbindungen
US6001347A (en) * 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US8163796B1 (en) 2009-07-28 2012-04-24 BioChemical Solutions, LLC Treatment of cancer by oxidation-reduction potentiation of cancerostatic dicarbonyls

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3048598A (en) * 1960-02-23 1962-08-07 Miles Lab Process for producing 2-hydrocarbon-2-dioxenes
US3555006A (en) * 1967-06-15 1971-01-12 Exxon Production Research Co Polysaccharide polymer cyclic ketals
GB1270579A (en) * 1968-08-17 1972-04-12 Fuji Photo Film Co Ltd Dihydroxy-1,4-dioxanes
BE759354A (fr) * 1969-11-28 1971-04-30 Fuji Photo Film Co Ltd Preparation de dihydroxy-1,4-dioxannes
US4096321A (en) * 1976-11-22 1978-06-20 Hoffmann-La Roche Inc. Process to produce oxazinomycin and intermediates
NL7904249A (nl) * 1978-06-20 1979-12-27 Cancer Res Nat Found Nieuwe cyclische acetalen met cytostatische, bloed- drukverlagende en pijnstillende werking, werkwijze ter bereiding van deze verbindingen alsmede farmaceu- tische preparaten die een dergelijke verbinding bevat- ten.

Also Published As

Publication number Publication date
JPS5649375A (en) 1981-05-02
AU5703780A (en) 1980-10-09
GB2061259B (en) 1983-02-02
IT1141269B (it) 1986-10-01
DE3010947C2 (de) 1986-08-07
FR2453171A1 (fr) 1980-10-31
SE8002549L (sv) 1980-10-07
NO800958L (no) 1980-10-07
NO151621C (no) 1985-05-08
CA1167859A (en) 1984-05-22
IE800626L (en) 1980-10-06
DE3010947A1 (de) 1980-10-23
GB2061259A (en) 1981-05-13
IE49434B1 (en) 1985-10-02
HU182119B (en) 1983-12-28
AU521764B2 (en) 1982-04-29
NL8001603A (nl) 1980-10-08
US4238500A (en) 1980-12-09
FR2453171B1 (hu) 1983-04-08
CH643550A5 (de) 1984-06-15
IT8021166A0 (it) 1980-04-03
DK150780A (da) 1980-10-07
NO151621B (no) 1985-01-28

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