SE442477B - Sett att framstella en komposition som fremjar en verkan mot aggregation av blodplettar innehallande prostacyklin - Google Patents

Sett att framstella en komposition som fremjar en verkan mot aggregation av blodplettar innehallande prostacyklin

Info

Publication number
SE442477B
SE442477B SE7711395A SE7711395A SE442477B SE 442477 B SE442477 B SE 442477B SE 7711395 A SE7711395 A SE 7711395A SE 7711395 A SE7711395 A SE 7711395A SE 442477 B SE442477 B SE 442477B
Authority
SE
Sweden
Prior art keywords
prostacycline
make
effect against
blood spots
against aggregation
Prior art date
Application number
SE7711395A
Other languages
English (en)
Other versions
SE7711395L (sv
Inventor
J R Vane
S Moncada
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of SE7711395L publication Critical patent/SE7711395L/sv
Publication of SE442477B publication Critical patent/SE442477B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
SE7711395A 1976-10-12 1977-10-11 Sett att framstella en komposition som fremjar en verkan mot aggregation av blodplettar innehallande prostacyklin SE442477B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB42280/76A GB1595056A (en) 1976-10-12 1976-10-12 Pharmaceutical combination

Publications (2)

Publication Number Publication Date
SE7711395L SE7711395L (sv) 1978-04-13
SE442477B true SE442477B (sv) 1986-01-13

Family

ID=10423728

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7711395A SE442477B (sv) 1976-10-12 1977-10-11 Sett att framstella en komposition som fremjar en verkan mot aggregation av blodplettar innehallande prostacyklin

Country Status (8)

Country Link
US (1) US4211782A (sv)
JP (1) JPS5356325A (sv)
DE (1) DE2745695A1 (sv)
FR (1) FR2367497A1 (sv)
GB (1) GB1595056A (sv)
HU (1) HU184219B (sv)
NL (1) NL7711153A (sv)
SE (1) SE442477B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
US4430340A (en) * 1978-07-17 1984-02-07 The Upjohn Company Stabilization of PGI2 compounds with surfactants
HU194734B (en) * 1985-07-11 1988-03-28 Jozsef Bara Process for production of medical and applicable for human consumption products suitable for treatment and/or prevention of diseases caused by free-radical reactions
DE3526362A1 (de) * 1985-07-19 1987-01-22 Schering Ag Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
US4778787A (en) * 1985-12-20 1988-10-18 Trustees Of Boston University Method for treatment of angina and myocardial infarctions with omental lipids
DE3719097C1 (de) * 1987-06-06 1988-06-09 Fratzer Uwe Arzneimittel,enthaltend Eicosapentaensaeure und Docosahexaensaeure als ungesaettigte Fettsaeuren sowie Vitamin E
US5043170A (en) * 1989-02-14 1991-08-27 Hoffmann-La Roche Inc. Animal feed composition containing a vitamin D metabolite
DE69327432T2 (de) * 1992-02-07 2000-05-18 Kaken Pharma Co Ltd Heilmittel für wunden und hämorrhoiden
US20040180865A1 (en) * 1993-06-04 2004-09-16 Jeffry W. Kreamer Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease
JP2001512484A (ja) * 1997-02-21 2001-08-21 ブリストル−マイヤーズ・スクイブ・カンパニー 虚血損傷を予防または軽減するためのレチノイド似活性を有する置換（５，６）−ジヒドロナフタレニル化合物の用途
DE69802465T2 (de) * 1997-05-29 2002-06-27 Sumitomo Chemical Co Polyalkoholderivate und Verfahren zur Herstellung davon
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
EP1648475B1 (en) 2003-07-09 2007-09-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Use of nitrite salts for the treatment of cardiovascular conditions
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US8142992B2 (en) * 2005-01-12 2012-03-27 Biovec Transfusion, Llc Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier
US7964338B2 (en) * 2005-01-12 2011-06-21 Biovec Transfusion, Llc Platelet preservation composition containing eptifibatide, a reversible factor IIa inhibitor and a hemoglobin oxygen carrier
US8557300B2 (en) * 2005-05-19 2013-10-15 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
WO2009086470A2 (en) * 2007-12-27 2009-07-09 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide - donating compounds and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2999049A (en) * 1959-03-27 1961-09-05 Wisconsin Alumni Res Found Warfarin sodium and heparin sodium composition
FR2405M (fr) * 1962-01-19 1964-03-16 Armour Pharma Compositions pour la prolongation du temps de coagulation du sang.
FR3552M (fr) * 1963-11-04 1965-09-20 Pierre Nouvelle association anticoagulante.
US3932656A (en) * 1970-09-10 1976-01-13 Alza Corporation Article of manufacture for instant release of anti-aggregation and non-thrombogenic agents to biological media
US3903266A (en) * 1972-05-03 1975-09-02 Ralph C Robbins Compositions and methods for disaggregating blood cells
NZ179580A (en) * 1974-12-30 1978-04-03 Mcneilab Inc 2-or 3-(w-tertiaryaminoalkyl)-thioindoles and the corresponding sulfinyl and sulfonyl analogs
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
JPS537665A (en) * 1976-05-11 1978-01-24 Wellcome Found Novel ether* its preparation and its use

Also Published As

Publication number Publication date
DE2745695A1 (de) 1978-04-13
JPS5356325A (en) 1978-05-22
US4211782A (en) 1980-07-08
FR2367497A1 (fr) 1978-05-12
SE7711395L (sv) 1978-04-13
HU184219B (en) 1984-07-30
NL7711153A (nl) 1978-04-14
FR2367497B1 (sv) 1980-02-01
GB1595056A (en) 1981-08-05

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