SE435935B - Sett att framstella nya isomera antibiotikaforeningar av tienamycintyp, benemnda 890a?712 och 890a?715, eller en blandning derav genom odling av stammar av streptomyces flavogriseus - Google Patents

Sett att framstella nya isomera antibiotikaforeningar av tienamycintyp, benemnda 890a?712 och 890a?715, eller en blandning derav genom odling av stammar av streptomyces flavogriseus

Info

Publication number
SE435935B
SE435935B SE7704301A SE7704301A SE435935B SE 435935 B SE435935 B SE 435935B SE 7704301 A SE7704301 A SE 7704301A SE 7704301 A SE7704301 A SE 7704301A SE 435935 B SE435935 B SE 435935B
Authority
SE
Sweden
Prior art keywords
tienamycine
stues
flavogrise
streptomyces
cultivation
Prior art date
Application number
SE7704301A
Other languages
English (en)
Swedish (sv)
Other versions
SE7704301L (sv
Inventor
P J Cassidy
R T Goegelman
E O Stapley
S Hernandez
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7704301L publication Critical patent/SE7704301L/xx
Publication of SE435935B publication Critical patent/SE435935B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7704301A 1976-04-28 1977-04-14 Sett att framstella nya isomera antibiotikaforeningar av tienamycintyp, benemnda 890a?712 och 890a?715, eller en blandning derav genom odling av stammar av streptomyces flavogriseus SE435935B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68083176A 1976-04-28 1976-04-28

Publications (2)

Publication Number Publication Date
SE7704301L SE7704301L (sv) 1977-10-29
SE435935B true SE435935B (sv) 1984-10-29

Family

ID=24732704

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7704301A SE435935B (sv) 1976-04-28 1977-04-14 Sett att framstella nya isomera antibiotikaforeningar av tienamycintyp, benemnda 890a?712 och 890a?715, eller en blandning derav genom odling av stammar av streptomyces flavogriseus

Country Status (11)

Country Link
US (2) US4168202A (fr)
JP (1) JPS52131596A (fr)
CH (1) CH634599A5 (fr)
DE (1) DE2718782A1 (fr)
DK (1) DK145504C (fr)
ES (1) ES458070A1 (fr)
FR (1) FR2349586A1 (fr)
GB (1) GB1547949A (fr)
NL (1) NL7704040A (fr)
PT (1) PT66476B (fr)
SE (1) SE435935B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808563A1 (de) * 1977-03-05 1978-09-07 Beecham Group Ltd Derivate der 3-thio-6-(1-hydroxyaethyl)-7-oxo-1-aza-bicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en- 2-carbonsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GR62185B (en) * 1977-03-31 1979-03-02 Panlabs Inc Preparation process of an antibiotic ps-5 and its derivatives with inhibitory activity of b-lactamase
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
EP0005348B1 (fr) * 1978-05-06 1982-09-22 Beecham Group Plc Dérivés de carbapénème, procédé pour leur préparation et compositions pharmaceutiques les contenant
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
EP0008885B1 (fr) * 1978-09-09 1983-11-30 Beecham Group Plc Composés de bêta-lactame, leur préparation et application
EP0033209B1 (fr) 1980-01-25 1984-06-13 Beecham Group Plc Composés dérivés de bêta-lactame, leur préparation et leur utilisation
US4409147A (en) * 1980-03-10 1983-10-11 Takeda Chemical Industries, Ltd. Carbapenem compounds and their production
JPS57109786A (en) * 1980-12-26 1982-07-08 Takeda Chem Ind Ltd Antibiotic c-19393e5 and its preparation
DE3827362A1 (de) * 1988-08-12 1990-02-15 Basf Ag Pulvrige, hydrophile theophyllinformulierung und verfahren zur ihrer herstellung
US5691191A (en) * 1996-03-15 1997-11-25 Agraquest, Inc. Medium for the cultivation of lagenidium giganteum
KR19990087785A (ko) * 1997-06-17 1999-12-27 파멜라 게일 마론 발효시세포수율을증가시키기위한영양배지
EP1429623B1 (fr) * 2001-08-27 2009-10-21 Advanced Bionutrition Corporation Apport de produits de lutte contre les maladies en aquaculture et agriculture au moyen d'aliments nutritionnels contenant des proteines bioactives produites par des virus
US7550647B2 (en) * 2001-09-14 2009-06-23 Advanced Bionutrition Transfected shrimp as production systems for therapeutic proteins
JP4472336B2 (ja) * 2001-09-14 2010-06-02 アドバンスド バイオニュートリション コーポレーション 治療用蛋白質の生産システムとしての甲殻類
US20060035310A1 (en) * 2004-08-13 2006-02-16 Millipore Corporation Media for recovery of microorganism in the presence of antibiotics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489235A (en) * 1974-03-28 1977-10-19 Beecham Group Ltd Antibiotics
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
DK143712C (da) * 1975-11-21 1982-03-22 Merck & Co Inc Fremgangsmaade til fremstilling af de antibiotiske stoffer 890a1 og 890a3

Also Published As

Publication number Publication date
US4141986A (en) 1979-02-27
DK145504B (da) 1982-11-29
DK145504C (da) 1983-04-25
PT66476A (en) 1977-05-01
DE2718782C2 (fr) 1989-11-30
NL7704040A (nl) 1977-11-01
DK163977A (da) 1977-10-29
JPS631315B2 (fr) 1988-01-12
SE7704301L (sv) 1977-10-29
PT66476B (en) 1979-03-12
JPS52131596A (en) 1977-11-04
GB1547949A (en) 1979-07-04
FR2349586A1 (fr) 1977-11-25
ES458070A1 (es) 1978-08-16
FR2349586B1 (fr) 1979-03-23
US4168202A (en) 1979-09-18
DE2718782A1 (de) 1977-11-17
CH634599A5 (de) 1983-02-15

Similar Documents

Publication Publication Date Title
SE435935B (sv) Sett att framstella nya isomera antibiotikaforeningar av tienamycintyp, benemnda 890a?712 och 890a?715, eller en blandning derav genom odling av stammar av streptomyces flavogriseus
SE431348B (sv) Forfarande for framstellning av ett nytt antibiotikum benemnt tienamycin genom odling av en ny stam streptomyces cattleya nrrl 8057
SE434277B (sv) Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
DK141022B (da) Fremgangsmåde til fremstilling af en antibiotisk blanding eller de enkelte komponenter betegnet teichomycin A1, teichomycin A2, teichomycin A3, antibiotisk 8327 faktor B og antibiotisk 8327 faktor C.
SE425798B (sv) Forfarande for framstellning av nya antitumor-antracyklinantibiotika benemnda ma 144 med sina utgivna formler genom odling av i och for sig forut kenda streptomycess-stammar och utvinning av de angivna substanserna
SE434065B (sv) Forfarande for framstellning av klavulansyra genom odling av streptomyces jumonjinensis
SE420195B (sv) Forfarande for utvinning av 1,3-butadien ur en kolveteblandning
SE426833B (sv) Forfarande for framstellning av nya gona-4,9(10)-diener
SE7608479L (sv) 4,5-dihydro-2-legre alkoxikarbonylamino-4-fenylimidazoler och substituerade fenylderivat derav och sett att framstella dessa foreningar
DK243477A (da) Fremgangsmade til fremstilling af 10,19-dihydrovitamin d forbindelser
SE435069B (sv) Forfarande for framstellning av nya antracyklinglykosider, benemnda rhodirubin a och b, genom odling av vissa stammar tillhorande slektet streptomyces
NO771870L (no) Fremgangsm}te for fremstilling av 3,4-dihydro-2-metyl-4-okso-2h-1,2-benzotiazin-3-karboksylsyre-1,1-dioksyd
SE7711228L (sv) (1-fenyl-2-triazolyl-etyl)-tioeter-derivat till anvendning som fungicider och tillvextregulatorer och sett att framstella foreningarna
SE385713B (sv) Framstellning av 7beta -(d-5-amino-5-karboxivaleramido)-3-(karbamoyloximetyl)-7-metoxi-3-cefem-4-karbonsyra genom odling av en ny mikroorganism benemd streptomyces lactamdurans nrrl 3802
SE426845B (sv) Framstellning av nya isomera antibiotika benemnda 890a, och 890a3 med angiven formel genom odling av streptomyces flavogriseus nrrl 8139 eller 8140
DK144765C (da) Fremgangsmaade til fremstilling af en antibiotisk blanding indeholdende forbindelse 41043 og forbindelse 41494, eller de enkelte komponenter i blandingen
SE436044B (sv) Sett att framstella nya depsipeptid-antibiotika, benemnda neoviridogrisein i, ii och iii, genom odling av streptomyces sp. p8648
SE432443B (sv) Forfarande for framstellning av nya antibiotika benemnda neotramycin a och b genom odling av en streptomyces-stam identifierad som atcc 31123
EG12114A (en) New compositions used as herbicides composed from certain substituted thiomethyl aryl ureas
SE7610310L (sv) Forfarande for framstellning av anthelmintiskt verksama 2-karbalkoxyamino-5(6)-fenylsulfonyl-oxybensimidazoler
DK148749C (da) Fremgangsmaade til fremstilling af en antibiotisk forbindelse betegnet 47.224 eller kationsalte deraf
JPS5340745A (en) Organophosphorus compound and chlorine-containing resin composition
SE433620B (sv) Sett att framstella antibiotikum 890 a?719 genom odling av streptomyces flavogriseus
SE432780B (sv) Sett att framstella ett nytt antibiotikum, n-acetyltienamycin och salter derav, genom odling av streptomyces cattleya nrrl 8057
DK278577A (da) Fremgangsmade til fremstilling af et antiotisk stof antibiotikum l 13365

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7704301-6

Effective date: 19931110

Format of ref document f/p: F