SE422581B - Analogiforfarande for framstellning av n-substituerade 3-hydroxi-8-oxamorfinaner - Google Patents

Analogiforfarande for framstellning av n-substituerade 3-hydroxi-8-oxamorfinaner

Info

Publication number
SE422581B
SE422581B SE7409253A SE7409253A SE422581B SE 422581 B SE422581 B SE 422581B SE 7409253 A SE7409253 A SE 7409253A SE 7409253 A SE7409253 A SE 7409253A SE 422581 B SE422581 B SE 422581B
Authority
SE
Sweden
Prior art keywords
oxamorphinanes
hydroxy
substituted
preparing
analogy procedure
Prior art date
Application number
SE7409253A
Other languages
English (en)
Other versions
SE7409253L (sv
Inventor
I Monkovic
Y Lambert
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE7409253L publication Critical patent/SE7409253L/xx
Publication of SE422581B publication Critical patent/SE422581B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE7409253A 1973-07-18 1974-07-15 Analogiforfarande for framstellning av n-substituerade 3-hydroxi-8-oxamorfinaner SE422581B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00380515A US3853889A (en) 1973-07-18 1973-07-18 3,14-substituted-8-oxamorphinans

Publications (2)

Publication Number Publication Date
SE7409253L SE7409253L (sv) 1975-01-20
SE422581B true SE422581B (sv) 1982-03-15

Family

ID=23501468

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7409253A SE422581B (sv) 1973-07-18 1974-07-15 Analogiforfarande for framstellning av n-substituerade 3-hydroxi-8-oxamorfinaner

Country Status (13)

Country Link
US (1) US3853889A (sv)
JP (1) JPS5835197B2 (sv)
BE (1) BE817755A (sv)
CA (1) CA1029722A (sv)
CH (2) CH605963A5 (sv)
DE (1) DE2434687A1 (sv)
DK (1) DK144094C (sv)
FR (1) FR2311540A1 (sv)
GB (1) GB1473896A (sv)
NL (1) NL7409743A (sv)
SE (1) SE422581B (sv)
YU (2) YU37478B (sv)
ZA (1) ZA744492B (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959290A (en) * 1973-07-18 1976-05-25 Bristol-Myers Company 3,14-Substituted-8-oxamorphinans
US3957793A (en) * 1974-09-20 1976-05-18 Sterling Drug Inc. Hydroxyiminobenzazocines
US3968114A (en) * 1974-09-20 1976-07-06 Sterling Drug Inc. 1,2,3,4,5,6,7,8,9,10-Decahydro-8-oxo-2,6-methano-3-benzazocines
US4032529A (en) * 1974-09-20 1977-06-28 Sterling Drug Inc. Aminomethanobenzazocine intermediates
US4016167A (en) * 1975-10-28 1977-04-05 Bristol-Myers Company N-Substituted-6,8-dioxamorphinans
US4127577A (en) * 1975-11-24 1978-11-28 Sterling Drug Inc. Aminomethanobenzazocine process
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
US4154932A (en) * 1977-09-08 1979-05-15 Bristol-Myers Company 6-Oxamorphinans
US4150032A (en) * 1978-01-18 1979-04-17 Bristol-Myers Company 9-Oxobenzomorphan process and intermediates
DE2857122T1 (de) * 1978-09-12 1980-12-04 Bristol Myers Co N-substituted-6-oxamorphinans
US4234731A (en) * 1979-01-05 1980-11-18 Bristol-Myers Company 9-Oxobenzomorphan process
US4228285A (en) * 1979-02-28 1980-10-14 Bristol-Myers Company 14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans
US4246413A (en) * 1979-05-14 1981-01-20 Bristol-Myers Company 6-Oxamorphinans
US4277605A (en) * 1980-03-07 1981-07-07 Bristol-Myers Company Chemical compounds
US7271173B2 (en) * 2002-11-18 2007-09-18 The Mclean Hospital Corporation Mixed kappa/mu opioids and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639407A (en) * 1965-05-05 1972-02-01 Geigy Chem Corp Novel 1 2 3 4 5 6-hexahydro-6-phenyl-2 6-methano-3-benzazocines
US3476757A (en) * 1966-04-18 1969-11-04 Syntex Corp Tetrahydropyranyl and tetrahydrofuranyl ethers of benzomorphans and morphanans
US3480638A (en) * 1966-11-10 1969-11-25 Geigy Chem Corp Derivatives of 5-hydroxyalkyl-6,7-benzomorphans
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3700734A (en) * 1969-01-23 1972-10-24 Merck & Co Inc 2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
US3732233A (en) * 1970-07-23 1973-05-08 Beecham Group Ltd Tetrahydromethano benzoxazocins and salts thereof

Also Published As

Publication number Publication date
DK383874A (sv) 1975-03-03
GB1473896A (en) 1977-05-18
NL7409743A (nl) 1975-01-21
BE817755A (fr) 1975-01-17
JPS5048000A (sv) 1975-04-28
FR2311540B1 (sv) 1979-05-18
AU7137574A (en) 1976-01-22
DE2434687A1 (de) 1975-02-06
SE7409253L (sv) 1975-01-20
DK144094C (da) 1982-05-10
DK144094B (da) 1981-12-07
FR2311540A1 (fr) 1976-12-17
ZA744492B (en) 1975-07-30
JPS5835197B2 (ja) 1983-08-01
CH605963A5 (sv) 1978-10-13
YU37478B (en) 1984-08-31
YU37346B (en) 1984-08-31
YU201674A (en) 1982-06-18
US3853889A (en) 1974-12-10
CH605962A5 (sv) 1978-10-13
YU324080A (en) 1983-04-27
CA1029722A (en) 1978-04-18

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