SE418401B - Sett att framstella kardiotona steroidforeningar innehallande en pyridazinring och glykosidderivat derav - Google Patents

Sett att framstella kardiotona steroidforeningar innehallande en pyridazinring och glykosidderivat derav

Info

Publication number
SE418401B
SE418401B SE7508908A SE7508908A SE418401B SE 418401 B SE418401 B SE 418401B SE 7508908 A SE7508908 A SE 7508908A SE 7508908 A SE7508908 A SE 7508908A SE 418401 B SE418401 B SE 418401B
Authority
SE
Sweden
Prior art keywords
gycloside
derivatives
make
compounds including
pyridazine ring
Prior art date
Application number
SE7508908A
Other languages
English (en)
Swedish (sv)
Other versions
SE7508908L (sv
Inventor
C Casagrande
G Ferrari
Original Assignee
Siphar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siphar Sa filed Critical Siphar Sa
Publication of SE7508908L publication Critical patent/SE7508908L/xx
Publication of SE418401B publication Critical patent/SE418401B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7508908A 1974-08-08 1975-08-07 Sett att framstella kardiotona steroidforeningar innehallande en pyridazinring och glykosidderivat derav SE418401B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1085574A CH621803A5 (xx) 1974-08-08 1974-08-08

Publications (2)

Publication Number Publication Date
SE7508908L SE7508908L (sv) 1976-02-09
SE418401B true SE418401B (sv) 1981-05-25

Family

ID=4367535

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7508908A SE418401B (sv) 1974-08-08 1975-08-07 Sett att framstella kardiotona steroidforeningar innehallande en pyridazinring och glykosidderivat derav

Country Status (12)

Country Link
US (1) US4000125A (xx)
JP (1) JPS5141372A (xx)
AR (1) AR217617A1 (xx)
BE (1) BE832271A (xx)
CA (1) CA1049499A (xx)
CH (1) CH621803A5 (xx)
DE (1) DE2534981A1 (xx)
DK (1) DK139101B (xx)
ES (1) ES440110A1 (xx)
FR (1) FR2281124A1 (xx)
GB (1) GB1484655A (xx)
SE (1) SE418401B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1144136B (it) * 1980-03-05 1986-10-29 Zenyaku Kogyo Kk Glucosidi di condurango agenti antitumorali che li comprendono e procedimento per la loro preparazione
US5373095A (en) * 1985-10-18 1994-12-13 The Upjohn Company Steroid compounds
IT1262931B (it) * 1992-01-16 1996-07-22 Zambon Spa Composti steroidei 17(piridazin-n-ossido)-sostituiti attivi sul sistema cardiovascolare
DE4227616C2 (de) * 1992-08-20 1995-04-13 Sigma Tau Ind Farmaceuti 17-(3-Furyl)-und 17-(4-Pyridazinyl)-5beta, 14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammemsetzungen
WO2006093993A1 (en) * 2005-03-02 2006-09-08 University Of Maryland Novel c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
WO2009114658A2 (en) * 2008-03-12 2009-09-17 University Of Maryland, Baltimore Androgen receptor inactivation contributes to antitumor efficacy of cyp17 inhibitors in prostate cancer
US20100048912A1 (en) * 2008-03-14 2010-02-25 Angela Brodie Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
US20110118219A1 (en) * 2008-03-25 2011-05-19 University Of Maryland, Baltimore Novel prodrugs of c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
WO2009129208A2 (en) * 2008-04-14 2009-10-22 University Of Maryland, Baltimore Compositions and methods of inducing endoplasmic reticulum stress reponse
GB2479693B (en) 2009-02-05 2014-04-09 Tokai Pharmaceuticals Inc Steroidal CYP17 inhibitors and their use in the treatment of cancer and prostate hyperplasia
BRPI1008745A2 (pt) 2009-02-05 2019-09-17 Tokai Pharmaceuticals Inc pró-fármacos de inibidores esteroidais de cyp17/antiandrogênios
WO2011017534A2 (en) 2009-08-07 2011-02-10 Tokai Pharmaceuticals, Inc. Treatment of prostate cancer
EP2968370A4 (en) 2013-03-14 2016-09-21 Univ Maryland AGENT FOR ANDROGEN RECEPTOR DOWNWARD CONTROL AND USES THEREOF
AU2014306698A1 (en) 2013-08-12 2016-01-28 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
WO2017001204A1 (en) * 2015-06-29 2017-01-05 Universiteit Gent Methods for the site-selective coupling of a first agent to a second agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3838163A (en) * 1968-11-22 1974-09-24 Hoffmann La Roche Substituted isoxazole derivatives as steroid intermediates

Also Published As

Publication number Publication date
DK139101C (xx) 1979-05-21
SE7508908L (sv) 1976-02-09
JPS5141372A (xx) 1976-04-07
DE2534981A1 (de) 1976-02-19
BE832271A (fr) 1975-12-01
GB1484655A (en) 1977-09-01
ES440110A1 (es) 1977-02-16
CA1049499A (en) 1979-02-27
AR217617A1 (es) 1980-04-15
FR2281124A1 (fr) 1976-03-05
DK358875A (xx) 1976-02-09
DK139101B (da) 1978-12-18
FR2281124B1 (xx) 1980-05-16
CH621803A5 (xx) 1981-02-27
US4000125A (en) 1976-12-28

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