SE387935B - Substituerade tetrahydro-5-oxo-4-indankarbonsyror och perhydro-2-oxo-1-naftalinkarbonsyror avsedda att anvendas vid syntes av 19-norsteroider - Google Patents

Substituerade tetrahydro-5-oxo-4-indankarbonsyror och perhydro-2-oxo-1-naftalinkarbonsyror avsedda att anvendas vid syntes av 19-norsteroider

Info

Publication number
SE387935B
SE387935B SE7216939A SE1693972A SE387935B SE 387935 B SE387935 B SE 387935B SE 7216939 A SE7216939 A SE 7216939A SE 1693972 A SE1693972 A SE 1693972A SE 387935 B SE387935 B SE 387935B
Authority
SE
Sweden
Prior art keywords
oxo
acids
nafthalincarbonic
indancarbonic
norsteroids
Prior art date
Application number
SE7216939A
Other languages
English (en)
Swedish (sv)
Inventor
Z G Hajos
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE387935B publication Critical patent/SE387935B/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/75—Reactions with formaldehyde
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/12—Saturated polycyclic compounds
    • C07C61/125—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
    • C07C61/13—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/18—Saturated compounds containing keto groups
    • C07C62/26—Saturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7216939A 1968-10-04 1969-10-03 Substituerade tetrahydro-5-oxo-4-indankarbonsyror och perhydro-2-oxo-1-naftalinkarbonsyror avsedda att anvendas vid syntes av 19-norsteroider SE387935B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US765023A US3897460A (en) 1968-10-04 1968-10-04 3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes

Publications (1)

Publication Number Publication Date
SE387935B true SE387935B (sv) 1976-09-20

Family

ID=25072426

Family Applications (5)

Application Number Title Priority Date Filing Date
SE13637/69A SE365196B (xx) 1968-10-04 1969-10-03
SE13638/69A SE365495B (xx) 1968-10-04 1969-10-03
SE7216952A SE389336B (sv) 1968-10-04 1969-10-03 Substituerade, hydroerade indan- och naftylforeningar avsedda att anvendas som mellanprodukter vid steroidsynteser.
SE7216953A SE389332B (sv) 1968-10-04 1969-10-03 Substituerade, hydrerade indan- och naftylforeningar avsedda att anvendas som mellanprodukter vid steroidsynteser.
SE7216939A SE387935B (sv) 1968-10-04 1969-10-03 Substituerade tetrahydro-5-oxo-4-indankarbonsyror och perhydro-2-oxo-1-naftalinkarbonsyror avsedda att anvendas vid syntes av 19-norsteroider

Family Applications Before (4)

Application Number Title Priority Date Filing Date
SE13637/69A SE365196B (xx) 1968-10-04 1969-10-03
SE13638/69A SE365495B (xx) 1968-10-04 1969-10-03
SE7216952A SE389336B (sv) 1968-10-04 1969-10-03 Substituerade, hydroerade indan- och naftylforeningar avsedda att anvendas som mellanprodukter vid steroidsynteser.
SE7216953A SE389332B (sv) 1968-10-04 1969-10-03 Substituerade, hydrerade indan- och naftylforeningar avsedda att anvendas som mellanprodukter vid steroidsynteser.

Country Status (13)

Country Link
US (1) US3897460A (xx)
JP (2) JPS5227157B1 (xx)
AT (3) AT296276B (xx)
BE (2) BE739719A (xx)
BR (3) BR6912947D0 (xx)
CH (1) CH527785A (xx)
DE (2) DE1949800C2 (xx)
DK (2) DK129282B (xx)
ES (4) ES372173A1 (xx)
FR (2) FR2019927A1 (xx)
GB (4) GB1244919A (xx)
NL (2) NL172231C (xx)
SE (5) SE365196B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979458A (en) * 1967-12-04 1976-09-07 Syntex Corporation Production of unsaturated carbocyclic ketones
US3975440A (en) * 1970-01-21 1976-08-17 Hoffmann-La Roche Inc. Asymmetric synthesis of organic compounds
DE2320285C2 (de) * 1973-04-18 1984-03-01 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von Bicycloalkan-Carbonsäuren
DE2409597C2 (de) * 1974-02-25 1983-12-29 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von Bicycloalkan-Carbonsäuren
CH583167A5 (xx) * 1973-04-18 1976-12-31 Schering Ag
US3971809A (en) * 1973-07-02 1976-07-27 Hoffmann-La Roche Inc. 3A,4,7,7A-Tetrahydro-4-phenylethyl-7a-alkyl-5(6H)-indanones and process for the preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3019252A (en) * 1959-06-18 1962-01-30 Lab Francais Chimiotherapie Process for the preparation of novel derivatives of cyclopentanonaphthalene and products obtained thereby
US3117979A (en) * 1960-01-22 1964-01-14 Roussel Uclaf Esters of 10beta-substituted 4, 5-seco-delta9(11)-19-nor-androstene-17beta-ol-3, 5-dines, intermediates and process
FR1364556A (fr) * 1962-03-06 1964-06-26 Roussel Uclaf Nouveau procédé de synthèse de stéroïdes et de composés apparentés et produits utilisés dans ce procédé
NL122142C (xx) * 1962-03-06

Also Published As

Publication number Publication date
ES372173A1 (es) 1971-09-16
AT291232B (de) 1971-07-12
SE365196B (xx) 1974-03-18
JPS52102259A (en) 1977-08-27
FR2019927A1 (xx) 1970-07-10
BE739719A (xx) 1970-04-02
BR6912947D0 (pt) 1973-02-15
DK138638C (xx) 1979-03-19
JPS5227157B1 (xx) 1977-07-19
CH527785A (de) 1972-09-15
NL172231B (nl) 1983-03-01
GB1244918A (en) 1971-09-02
FR2019928A1 (xx) 1970-07-10
BR6912949D0 (pt) 1973-02-15
DK138638B (da) 1978-10-09
BR6912946D0 (pt) 1973-02-15
NL6914989A (xx) 1970-04-07
DK129282C (xx) 1975-02-10
SE389336B (sv) 1976-11-01
DK129282B (da) 1974-09-23
NL6914988A (xx) 1970-04-07
GB1244919A (en) 1971-09-02
ES372174A1 (es) 1971-09-16
DE1949800C2 (de) 1982-04-15
ES400148A1 (es) 1974-12-16
AT296276B (de) 1972-02-10
DE1949800A1 (de) 1970-05-06
ES400147A1 (es) 1974-12-16
BE739718A (xx) 1970-04-02
DE1949793A1 (de) 1970-05-06
AT291233B (de) 1971-07-12
GB1224587A (en) 1971-03-10
US3897460A (en) 1975-07-29
SE389332B (sv) 1976-11-01
GB1224588A (en) 1971-03-10
NL172231C (nl) 1983-08-01
SE365495B (xx) 1974-03-25

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