SE380269B - Komplex av n,n-dimetylformamid och cefalexin samt av n,n-dimetylacetamid och cefalexin till anvendning som mellanprodukt for framstellning av cefalexin - Google Patents

Komplex av n,n-dimetylformamid och cefalexin samt av n,n-dimetylacetamid och cefalexin till anvendning som mellanprodukt for framstellning av cefalexin

Info

Publication number
SE380269B
SE380269B SE7200477A SE47772A SE380269B SE 380269 B SE380269 B SE 380269B SE 7200477 A SE7200477 A SE 7200477A SE 47772 A SE47772 A SE 47772A SE 380269 B SE380269 B SE 380269B
Authority
SE
Sweden
Prior art keywords
cefalexin
dimethylacetamide
dimethylformamide
complex
intermediate product
Prior art date
Application number
SE7200477A
Other languages
English (en)
Swedish (sv)
Inventor
W L Garbrecht
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22320939&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE380269(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE380269B publication Critical patent/SE380269B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
SE7200477A 1971-01-20 1972-01-07 Komplex av n,n-dimetylformamid och cefalexin samt av n,n-dimetylacetamid och cefalexin till anvendning som mellanprodukt for framstellning av cefalexin SE380269B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10821871A 1971-01-20 1971-01-20

Publications (1)

Publication Number Publication Date
SE380269B true SE380269B (sv) 1975-11-03

Family

ID=22320939

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7200477A SE380269B (sv) 1971-01-20 1972-01-07 Komplex av n,n-dimetylformamid och cefalexin samt av n,n-dimetylacetamid och cefalexin till anvendning som mellanprodukt for framstellning av cefalexin

Country Status (26)

Country Link
US (1) US3781282A (it)
JP (1) JPS5544076B1 (it)
AR (1) AR194722A1 (it)
AT (1) AT314731B (it)
BE (1) BE777789A (it)
BG (1) BG21611A3 (it)
CA (1) CA1010848A (it)
CH (1) CH547311A (it)
CS (1) CS187354B2 (it)
DK (1) DK142950C (it)
ES (1) ES398963A1 (it)
FI (1) FI60565C (it)
FR (1) FR2122987A5 (it)
GB (1) GB1336802A (it)
HU (1) HU167270B (it)
IE (1) IE35964B1 (it)
IL (1) IL38565A (it)
LU (1) LU64635A1 (it)
NL (1) NL172746C (it)
NO (1) NO143158C (it)
PH (1) PH9590A (it)
PL (1) PL83085B1 (it)
SE (1) SE380269B (it)
SU (1) SU592360A3 (it)
YU (1) YU39454B (it)
ZA (1) ZA7250B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52106891A (en) * 1976-03-03 1977-09-07 Shionogi & Co Ltd Removal of carboxyl protecting group
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4091214A (en) * 1977-02-25 1978-05-23 Eli Lilly And Company De-esterification process for cephalosporins
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
AR223653A1 (es) * 1977-09-27 1981-09-15 Toyama Chemical Co Ltd Procedimiento de preparacion del acido 7-(d(-)-alpha-(4-etil-2,3-dioxo-1-piperazinocarboxamido)-alpha-(4-hidroxifenil)acetamido)-3-(5-(1-metil-1,2,3,4-tetrazolil)tiometil)-delta3-cefem-4-carboxilico y su producto de adicion con n,n-dimetilacetamida
AT363594B (de) * 1978-02-01 1981-08-10 Biochemie Gmbh Verfahren zur herstellung eines neuen formamidkomplexes von 7-beta-(d-2-amino-2-phenylacetamido)-3-methylceph-3-emcarbonsaeure
DE3138409A1 (de) * 1981-09-26 1983-04-21 Robert Bosch Gmbh, 7000 Stuttgart "kraftstoffeinspritzpumpe fuer brennkraftmaschinen"
FR2555989B1 (fr) * 1983-12-06 1987-02-20 Bristol Myers Sa Monohydrate de chlorocephadroxyle
JPS60114271U (ja) * 1984-01-12 1985-08-02 株式会社ボッシュオートモーティブ　システム 流体ポンプ
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
WO1991000865A1 (en) * 1989-07-10 1991-01-24 Gema S.A. A novel stable form of cephradine, process for its production and intermediates used therein
US5278157A (en) * 1989-07-10 1994-01-11 Gema, S.A. Stable cephradine hydrate
IN181697B (it) * 1994-04-22 1998-09-05 Ranbaxy Lab Ltd
DE69601051T2 (de) * 1995-05-30 1999-06-10 Ranbaxy Laboratories, Ltd., New Delhi Verfahren zur Spaltung von p-Nitrobenzylester in Cephalosporin
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
EP2024374A1 (en) * 2006-05-19 2009-02-18 DSMIP Assets B.V. Process for the crystallisation of cefadroxil

Also Published As

Publication number Publication date
SU592360A3 (ru) 1978-02-05
AR194722A1 (es) 1973-08-14
JPS5544076B1 (it) 1980-11-10
NL172746C (nl) 1983-10-17
PL83085B1 (it) 1975-12-31
PH9590A (en) 1976-01-19
ES398963A1 (es) 1974-10-16
CS187354B2 (en) 1979-01-31
FR2122987A5 (it) 1972-09-01
BG21611A3 (bg) 1976-07-20
CA1010848A (en) 1977-05-24
NL172746B (nl) 1983-05-16
DE2202227A1 (de) 1972-11-30
GB1336802A (en) 1973-11-14
NL7200712A (it) 1972-07-24
HU167270B (it) 1975-09-27
NO143158B (no) 1980-09-15
YU39454B (en) 1984-12-31
IE35964B1 (en) 1976-07-07
LU64635A1 (it) 1972-08-23
FI60565B (fi) 1981-10-30
AT314731B (de) 1974-04-25
DK142950B (da) 1981-03-02
IE35964L (en) 1972-07-20
YU11872A (en) 1982-02-28
IL38565A (en) 1975-02-10
FI60565C (fi) 1982-02-10
ZA7250B (en) 1973-08-29
CH547311A (fr) 1974-03-29
DK142950C (da) 1981-10-05
NO143158C (no) 1980-12-29
US3781282A (en) 1973-12-25
IL38565A0 (en) 1972-03-28
DE2202227B2 (de) 1976-05-26
BE777789A (fr) 1972-07-06

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