NL172746C - Werkwijze ter bereiding van een complex van cefalexine en n.n-dimethylformamide of n.n-dimethylaceetamide. - Google Patents

Werkwijze ter bereiding van een complex van cefalexine en n.n-dimethylformamide of n.n-dimethylaceetamide.

Info

Publication number
NL172746C
NL172746C NLAANVRAGE7200712,A NL7200712A NL172746C NL 172746 C NL172746 C NL 172746C NL 7200712 A NL7200712 A NL 7200712A NL 172746 C NL172746 C NL 172746C
Authority
NL
Netherlands
Prior art keywords
cephalexin
dimethylacetamide
dimethylformamide
preparing
complex
Prior art date
Application number
NLAANVRAGE7200712,A
Other languages
English (en)
Other versions
NL172746B (nl
NL7200712A (nl
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22320939&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL172746(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NL7200712A publication Critical patent/NL7200712A/xx
Publication of NL172746B publication Critical patent/NL172746B/nl
Application granted granted Critical
Publication of NL172746C publication Critical patent/NL172746C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
NLAANVRAGE7200712,A 1971-01-20 1972-01-18 Werkwijze ter bereiding van een complex van cefalexine en n.n-dimethylformamide of n.n-dimethylaceetamide. NL172746C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10821871A 1971-01-20 1971-01-20

Publications (3)

Publication Number Publication Date
NL7200712A NL7200712A (nl) 1972-07-24
NL172746B NL172746B (nl) 1983-05-16
NL172746C true NL172746C (nl) 1983-10-17

Family

ID=22320939

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7200712,A NL172746C (nl) 1971-01-20 1972-01-18 Werkwijze ter bereiding van een complex van cefalexine en n.n-dimethylformamide of n.n-dimethylaceetamide.

Country Status (26)

Country Link
US (1) US3781282A (nl)
JP (1) JPS5544076B1 (nl)
AR (1) AR194722A1 (nl)
AT (1) AT314731B (nl)
BE (1) BE777789A (nl)
BG (1) BG21611A3 (nl)
CA (1) CA1010848A (nl)
CH (1) CH547311A (nl)
CS (1) CS187354B2 (nl)
DK (1) DK142950C (nl)
ES (1) ES398963A1 (nl)
FI (1) FI60565C (nl)
FR (1) FR2122987A5 (nl)
GB (1) GB1336802A (nl)
HU (1) HU167270B (nl)
IE (1) IE35964B1 (nl)
IL (1) IL38565A (nl)
LU (1) LU64635A1 (nl)
NL (1) NL172746C (nl)
NO (1) NO143158C (nl)
PH (1) PH9590A (nl)
PL (1) PL83085B1 (nl)
SE (1) SE380269B (nl)
SU (1) SU592360A3 (nl)
YU (1) YU39454B (nl)
ZA (1) ZA7250B (nl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52106891A (en) * 1976-03-03 1977-09-07 Shionogi & Co Ltd Removal of carboxyl protecting group
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4091214A (en) * 1977-02-25 1978-05-23 Eli Lilly And Company De-esterification process for cephalosporins
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
AR223653A1 (es) * 1977-09-27 1981-09-15 Toyama Chemical Co Ltd Procedimiento de preparacion del acido 7-(d(-)-alpha-(4-etil-2,3-dioxo-1-piperazinocarboxamido)-alpha-(4-hidroxifenil)acetamido)-3-(5-(1-metil-1,2,3,4-tetrazolil)tiometil)-delta3-cefem-4-carboxilico y su producto de adicion con n,n-dimetilacetamida
AT363594B (de) * 1978-02-01 1981-08-10 Biochemie Gmbh Verfahren zur herstellung eines neuen formamidkomplexes von 7-beta-(d-2-amino-2-phenylacetamido)-3-methylceph-3-emcarbonsaeure
DE3138409A1 (de) * 1981-09-26 1983-04-21 Robert Bosch Gmbh, 7000 Stuttgart "kraftstoffeinspritzpumpe fuer brennkraftmaschinen"
FR2555989B1 (fr) * 1983-12-06 1987-02-20 Bristol Myers Sa Monohydrate de chlorocephadroxyle
JPS60114271U (ja) * 1984-01-12 1985-08-02 株式会社ボッシュオートモーティブ　システム 流体ポンプ
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
ES2023560A6 (es) * 1989-07-10 1992-01-16 Gema Sa Procedimiento para la produccion de hidrato de cefradina y solvato de cefradina y dimetilformamida.
US5278157A (en) * 1989-07-10 1994-01-11 Gema, S.A. Stable cephradine hydrate
IN181697B (nl) * 1994-04-22 1998-09-05 Ranbaxy Lab Ltd
EP0745603B1 (en) * 1995-05-30 1998-12-02 Ranbaxy Laboratories Limited Process for p-nitrobenzyl ester cleavage in cephalosporin
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
ES2609633T3 (es) * 2006-05-19 2017-04-21 Dsm Sinochem Pharmaceuticals Netherlands B.V. Proceso para la cristalización de cefadroxilo monohidrato

Also Published As

Publication number Publication date
CH547311A (fr) 1974-03-29
US3781282A (en) 1973-12-25
PH9590A (en) 1976-01-19
FI60565C (fi) 1982-02-10
ZA7250B (en) 1973-08-29
AR194722A1 (es) 1973-08-14
DE2202227B2 (de) 1976-05-26
DE2202227A1 (de) 1972-11-30
IE35964B1 (en) 1976-07-07
IE35964L (en) 1972-07-20
CS187354B2 (en) 1979-01-31
DK142950C (da) 1981-10-05
BE777789A (fr) 1972-07-06
YU39454B (en) 1984-12-31
SE380269B (sv) 1975-11-03
FR2122987A5 (nl) 1972-09-01
CA1010848A (en) 1977-05-24
PL83085B1 (nl) 1975-12-31
NL172746B (nl) 1983-05-16
IL38565A0 (en) 1972-03-28
ES398963A1 (es) 1974-10-16
YU11872A (en) 1982-02-28
GB1336802A (en) 1973-11-14
SU592360A3 (ru) 1978-02-05
AT314731B (de) 1974-04-25
NO143158C (no) 1980-12-29
FI60565B (fi) 1981-10-30
DK142950B (da) 1981-03-02
BG21611A3 (bg) 1976-07-20
IL38565A (en) 1975-02-10
HU167270B (nl) 1975-09-27
LU64635A1 (nl) 1972-08-23
NO143158B (no) 1980-09-15
JPS5544076B1 (nl) 1980-11-10
NL7200712A (nl) 1972-07-24

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Legal Events

Date Code Title Description
V4 Discontinued because of reaching the maximum lifetime of a patent