SE343060B - - Google Patents
Info
- Publication number
- SE343060B SE343060B SE5222/68A SE522268A SE343060B SE 343060 B SE343060 B SE 343060B SE 5222/68 A SE5222/68 A SE 5222/68A SE 522268 A SE522268 A SE 522268A SE 343060 B SE343060 B SE 343060B
- Authority
- SE
- Sweden
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US118243A US3405122A (en) | 1961-06-20 | 1961-06-20 | Novel 3h-1, 4-benzodiazepin-2-(1h)-ones |
| US130757A US3100770A (en) | 1961-06-20 | 1961-08-11 | 5-pyridyl-1,4-benzodiazepine compounds |
| US326340A US3398159A (en) | 1961-06-20 | 1963-11-27 | Aminophenyl heterocyclic ketones |
| US326341A US3407211A (en) | 1961-06-20 | 1963-11-27 | Acylaminophenyl heterocyclic ketones |
| US326338A US3400128A (en) | 1961-06-20 | 1963-11-27 | Heterocyclic intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE343060B true SE343060B (no) | 1972-02-28 |
Family
ID=27537521
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE6895/62A SE301811B (no) | 1961-06-20 | 1962-06-20 | |
| SE3477/64A SE303752B (no) | 1961-06-20 | 1962-06-20 | |
| SE1640067A SE317682B (no) | 1961-06-20 | 1967-11-29 | |
| SE5222/68A SE343060B (no) | 1961-06-20 | 1968-04-18 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE6895/62A SE301811B (no) | 1961-06-20 | 1962-06-20 | |
| SE3477/64A SE303752B (no) | 1961-06-20 | 1962-06-20 | |
| SE1640067A SE317682B (no) | 1961-06-20 | 1967-11-29 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US3405122A (no) |
| CH (4) | CH445501A (no) |
| DE (1) | DE1445862A1 (no) |
| FR (1) | FR1978M (no) |
| GB (1) | GB948888A (no) |
| NL (4) | NL6700180A (no) |
| SE (4) | SE301811B (no) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3261828A (en) * | 1962-10-04 | 1966-07-19 | Hoffmann La Roche | 3h-1,4-benzodiazepine-2,5(1h,4h)-dione compounds |
| US3184448A (en) * | 1962-10-16 | 1965-05-18 | American Home Prod | Benzodiazepinium compounds |
| US3336296A (en) * | 1962-10-26 | 1967-08-15 | American Home Prod | Preparation of 5-substituted-2h-1, 4-benzodiazepin-2-one-4-oxides |
| US3192199A (en) * | 1963-03-01 | 1965-06-29 | Freeman H Mcmillan | Process for the production of 1-cycloalkyl derivatives of 1, 4-benzodiazepine |
| US3321467A (en) * | 1963-11-27 | 1967-05-23 | Hoffmann La Roche | 3-halo-1, 4-benzodiazepin-2-ones |
| US3182067A (en) * | 1964-04-09 | 1965-05-04 | Hoffmann La Roche | Benzodiazepine compounds |
| NL131731C (no) * | 1965-12-09 | |||
| US3678043A (en) * | 1966-03-14 | 1972-07-18 | American Home Prod | 2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-3-carboxylic acid esters and related compounds |
| US3429874A (en) * | 1966-12-22 | 1969-02-25 | Schering Corp | 1-polyhalogenoalkyl-2-oxo-1,3-dihydro-2h-1,4-benzodiazepines |
| US3506403A (en) * | 1967-12-19 | 1970-04-14 | Hoffmann La Roche | Colorimetric method for determining iron in fluids |
| US3506404A (en) * | 1967-12-19 | 1970-04-14 | Hoffmann La Roche | Colorimetric method for determining iron in blood |
| US3551427A (en) * | 1969-05-09 | 1970-12-29 | Sandoz Ag | 4-thienyl-2-(1h)-quinazolones |
| US3856802A (en) * | 1971-05-10 | 1974-12-24 | Upjohn Co | 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES |
| US4089953A (en) * | 1973-06-20 | 1978-05-16 | Ddsa Pharmaceuticals | 1,5-Benzodiazocines |
| DE3124013A1 (de) * | 1981-06-19 | 1982-12-30 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| IE903879A1 (en) * | 1989-10-30 | 1991-05-08 | Hoffmann La Roche | Use of a benzodiazepine and a phenylpyrrylketone derivative |
| US5036101A (en) * | 1989-10-30 | 1991-07-30 | Hoffmann-La Roche Inc. | Method for treating retroviral infections with aryl-(2-pyrryl) ketone compound |
| US5164376A (en) * | 1989-10-30 | 1992-11-17 | Hoffmann-Laroche Inc. | Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound |
| US5041438A (en) * | 1989-10-30 | 1991-08-20 | Hoffmann-La Roche Inc. | Method for treating retroviral infections with benzodiazepine compounds |
| US5141735A (en) * | 1990-06-18 | 1992-08-25 | Hoffman-La Roche, Inc. | Substituted amino-benzodiazepines having anitviral activity |
| EP0491218A1 (en) * | 1990-12-17 | 1992-06-24 | F. Hoffmann-La Roche Ag | Benzodiazepinones |
| JPH06501502A (ja) * | 1992-02-26 | 1994-02-17 | エフ・ホフマン−ラ ロシユ アーゲー | ベンゾジアゼピノン類 |
| SI9300288A (sl) | 1992-06-16 | 1993-12-31 | Hoffmann La Roche | Benzodiazepini |
| US5641773A (en) * | 1993-11-30 | 1997-06-24 | Dana-Farber Cancer Institute | Methods for treating viral infections |
| WO2002098865A2 (fr) * | 2001-06-07 | 2002-12-12 | Neuro3D | Inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations de ces inhibiteurs |
| DE10161767A1 (de) * | 2001-12-15 | 2003-06-26 | Merck Patent Gmbh | 2-Guanidino-4-heterocyclyl-chinazoline |
| EP2685985B1 (en) | 2011-03-17 | 2016-08-31 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Methods for treating leukemia and disorders mediated by cbf and runx1 proteins |
| WO2018093797A1 (en) | 2016-11-15 | 2018-05-24 | The Schepens Eye Research Institute, Inc. | Compositions and methods for the treatment of aberrant angiogenesis |
| US11583497B2 (en) | 2017-11-14 | 2023-02-21 | The Schepens Eye Research Institute, Inc. | Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery |
| CA3082643A1 (en) | 2017-11-14 | 2019-05-23 | The Schepens Eye Research Institute, Inc. | Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition |
| CN107903244B (zh) * | 2017-11-29 | 2019-06-14 | 武汉珈创生物技术股份有限公司 | 具有抗肿瘤活性的2-胺基取代苯并二氮卓化合物及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2928837A (en) * | 1960-03-15 | Chj-chj | ||
| US2998421A (en) * | 1961-08-29 | Guanroevo compounds and method of | ||
| US2997479A (en) * | 1955-07-01 | 1961-08-22 | Endo Lab | 1, 1-diphenyl-1-hydroxy-4-(pyrrolidyl)-butanone-2 |
| US2962503A (en) * | 1956-11-21 | 1960-11-29 | American Cyanamid Co | Nitropyrroles |
| US2944056A (en) * | 1957-05-22 | 1960-07-05 | Sumitomo Chemical Co | Method of producing quinazoline derivatives |
| CH370076A (de) * | 1959-01-09 | 1963-06-30 | Cilag Chemie Aktiengesellschaf | Verfahren zur Herstellung neuer jodierter Säureamide |
| US2993905A (en) * | 1959-04-24 | 1961-07-25 | Us Vitamin Pharm Corp | Nu-dialkylaminoalkyl, nu-pyridylethyl anilines |
| US2999091A (en) * | 1959-10-23 | 1961-09-05 | Abbott Lab | 3,9-diazabicyclo[4.2.1]nonane derivatives |
| US3336295A (en) * | 1960-12-02 | 1967-08-15 | Hoffmann La Roche | Hydroxy or alkoxy substituted 5-phenyl-3h-1, 4-benzodiazepin-2(1h)-ones |
-
0
- NL NL131733D patent/NL131733C/xx active
- NL NL279830D patent/NL279830A/xx unknown
- NL NL122319D patent/NL122319C/xx active
-
1961
- 1961-06-20 US US118243A patent/US3405122A/en not_active Expired - Lifetime
- 1961-08-11 US US130757A patent/US3100770A/en not_active Expired - Lifetime
-
1962
- 1962-06-14 CH CH734566A patent/CH445501A/de unknown
- 1962-06-14 CH CH1591566A patent/CH450438A/de unknown
- 1962-06-14 CH CH734666A patent/CH445502A/de unknown
- 1962-06-14 CH CH712762A patent/CH425808A/de unknown
- 1962-06-16 DE DE19621445862 patent/DE1445862A1/de active Pending
- 1962-06-19 FR FR901235A patent/FR1978M/fr active Active
- 1962-06-19 GB GB23491/62A patent/GB948888A/en not_active Expired
- 1962-06-20 SE SE6895/62A patent/SE301811B/xx unknown
- 1962-06-20 SE SE3477/64A patent/SE303752B/xx unknown
-
1963
- 1963-11-27 US US326338A patent/US3400128A/en not_active Expired - Lifetime
- 1963-11-27 US US326340A patent/US3398159A/en not_active Expired - Lifetime
- 1963-11-27 US US326341A patent/US3407211A/en not_active Expired - Lifetime
-
1967
- 1967-01-05 NL NL6700180A patent/NL6700180A/xx unknown
- 1967-11-29 SE SE1640067A patent/SE317682B/xx unknown
-
1968
- 1968-04-18 SE SE5222/68A patent/SE343060B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3400128A (en) | 1968-09-03 |
| NL122319C (no) | |
| FR1978M (fr) | 1963-08-19 |
| US3100770A (en) | 1963-08-13 |
| NL279830A (no) | |
| SE301811B (no) | 1968-06-24 |
| GB948888A (en) | 1964-02-05 |
| NL131733C (no) | |
| NL6700180A (no) | 1967-03-28 |
| US3407211A (en) | 1968-10-22 |
| SE317682B (no) | 1969-11-24 |
| US3405122A (en) | 1968-10-08 |
| CH445502A (de) | 1967-10-31 |
| CH445501A (de) | 1967-10-31 |
| SE303752B (no) | 1968-09-09 |
| CH450438A (de) | 1968-01-31 |
| DE1445862A1 (de) | 1969-01-30 |
| US3398159A (en) | 1968-08-20 |
| CH425808A (de) | 1966-12-15 |