SE319577B - - Google Patents

Info

Publication number
SE319577B
SE319577B SE303166A SE303166A SE319577B SE 319577 B SE319577 B SE 319577B SE 303166 A SE303166 A SE 303166A SE 303166 A SE303166 A SE 303166A SE 319577 B SE319577 B SE 319577B
Authority
SE
Sweden
Prior art keywords
chlormethiazole
march
stabilized
composition
mixture
Prior art date
Application number
SE303166A
Inventor
T Rydh
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE303166A priority Critical patent/SE319577B/xx
Priority to NL6702002A priority patent/NL156921B/en
Priority to DE1967A0054844 priority patent/DE1617286B1/en
Priority to BE693977D priority patent/BE693977A/xx
Priority to AT151867A priority patent/AT266126B/en
Priority to GB976267A priority patent/GB1147731A/en
Publication of SE319577B publication Critical patent/SE319577B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

1,147,731. Stabilized chlormethiazole compositions. ASTRA A.B. 1 March, 1967 [8 March, 1966], No. 9762/67. Heading A5B. A stabilized pharmaceutical composition comprising chlormethiazole is produced by forming an intimate mixture of chlormethiazole and a non-polar, non-toxic carrier selected from peanut oil, oleic acid, stearyl alcohol, stearic acid and mixtures of these carriers, in which mixture the amount of chlormethiazole is 20-85 percent by weight, based on the total weight of chlormethiazole and carrier. The composition may be in the form of a dosage unit comprising the above composition enclosed in a capsule of a watersoluble pharmaceutically acceptable solid material, e.g. gelatin.
SE303166A 1966-03-08 1966-03-08 SE319577B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE303166A SE319577B (en) 1966-03-08 1966-03-08
NL6702002A NL156921B (en) 1966-03-08 1967-02-09 PROCESS FOR THE PREPARATION OF A THERAPEUTIC PREPARATION CONTAINING AS THE ACTIVE INGREDIENT 4-METHYL-5- (2'-CHLORETHYL) -THIA SOLE AND FORMED THERAPEUTIC PREPARED UNDER THIS PROCESS.
DE1967A0054844 DE1617286B1 (en) 1966-03-08 1967-02-09 Medicinal product based on 4-methyl-5- (2'-chloroethyl) -thiazole
BE693977D BE693977A (en) 1966-03-08 1967-02-13
AT151867A AT266126B (en) 1966-03-08 1967-02-16 Process for the stabilization of 4-methyl-5- (2'-chloroethyl) -thiazole
GB976267A GB1147731A (en) 1966-03-08 1967-03-01 Improvements relating to the stabilization of chlormethiazole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE303166A SE319577B (en) 1966-03-08 1966-03-08

Publications (1)

Publication Number Publication Date
SE319577B true SE319577B (en) 1970-01-19

Family

ID=20261249

Family Applications (1)

Application Number Title Priority Date Filing Date
SE303166A SE319577B (en) 1966-03-08 1966-03-08

Country Status (6)

Country Link
AT (1) AT266126B (en)
BE (1) BE693977A (en)
DE (1) DE1617286B1 (en)
GB (1) GB1147731A (en)
NL (1) NL156921B (en)
SE (1) SE319577B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT358530B (en) * 1978-04-25 1980-09-10 Plc Pharma Licences STABILIZATION PROCEDURE

Also Published As

Publication number Publication date
AT266126B (en) 1968-11-11
BE693977A (en) 1967-08-14
DE1617286B1 (en) 1971-05-27
NL6702002A (en) 1967-09-11
NL156921B (en) 1978-06-15
GB1147731A (en) 1969-04-02

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