SE199837C1 - - Google Patents
Info
- Publication number
- SE199837C1 SE199837C1 SE199837DA SE199837C1 SE 199837 C1 SE199837 C1 SE 199837C1 SE 199837D A SE199837D A SE 199837DA SE 199837 C1 SE199837 C1 SE 199837C1
- Authority
- SE
- Sweden
- Prior art keywords
- compounds
- disulfonamide
- heated
- halobenzene
- give
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims description 13
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 5
- 229910021529 ammonia Inorganic materials 0.000 claims description 4
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 claims description 4
- KEQGZUUPPQEDPF-UHFFFAOYSA-N 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione Chemical compound CC1(C)N(Cl)C(=O)N(Cl)C1=O KEQGZUUPPQEDPF-UHFFFAOYSA-N 0.000 claims description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 3
- XTHPWXDJESJLNJ-UHFFFAOYSA-N chlorosulfonic acid Substances OS(Cl)(=O)=O XTHPWXDJESJLNJ-UHFFFAOYSA-N 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 150000002367 halogens Chemical group 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 229910052783 alkali metal Inorganic materials 0.000 description 3
- -1 alkali metal salts Chemical class 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- ISPYQTSUDJAMAB-UHFFFAOYSA-N 2-chlorophenol Chemical compound OC1=CC=CC=C1Cl ISPYQTSUDJAMAB-UHFFFAOYSA-N 0.000 description 2
- WKDNROIOJLGMTQ-UHFFFAOYSA-N 5-bromo-4-chlorobenzene-1,3-disulfonamide Chemical compound NS(=O)(=O)C1=CC(Br)=C(Cl)C(S(N)(=O)=O)=C1 WKDNROIOJLGMTQ-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000012043 crude product Substances 0.000 description 2
- GJQPMPFPNINLKP-UHFFFAOYSA-N diclofenamide Chemical compound NS(=O)(=O)C1=CC(Cl)=C(Cl)C(S(N)(=O)=O)=C1 GJQPMPFPNINLKP-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- VADKRMSMGWJZCF-UHFFFAOYSA-N 2-bromophenol Chemical compound OC1=CC=CC=C1Br VADKRMSMGWJZCF-UHFFFAOYSA-N 0.000 description 1
- DELKNGSNILXDSN-UHFFFAOYSA-N 4,5-dichlorobenzene-1,3-disulfonyl chloride Chemical compound ClC1=CC(S(Cl)(=O)=O)=CC(S(Cl)(=O)=O)=C1Cl DELKNGSNILXDSN-UHFFFAOYSA-N 0.000 description 1
- RJMGUEXGQXNUBI-UHFFFAOYSA-N 5-chloro-4-hydroxybenzene-1,3-disulfonyl chloride Chemical compound OC1=C(Cl)C=C(S(Cl)(=O)=O)C=C1S(Cl)(=O)=O RJMGUEXGQXNUBI-UHFFFAOYSA-N 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 241000408659 Darpa Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 231100000229 OECD 452 Chronic Toxicity Study Toxicity 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 description 1
- 150000001447 alkali salts Chemical class 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- HUYYFHGIHVULSU-UHFFFAOYSA-N benzene-1-3-disulfonamide Chemical compound NS(=O)(=O)C1=CC=CC(S(N)(=O)=O)=C1 HUYYFHGIHVULSU-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- FOCAUTSVDIKZOP-UHFFFAOYSA-N chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 description 1
- 229940106681 chloroacetic acid Drugs 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 230000001452 natriuretic effect Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE199837T |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE199837C1 true SE199837C1 (enrdf_load_stackoverflow) | 1965-01-01 |
Family
ID=41984527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE199837D SE199837C1 (enrdf_load_stackoverflow) |
Country Status (1)
| Country | Link |
|---|---|
| SE (1) | SE199837C1 (enrdf_load_stackoverflow) |
-
0
- SE SE199837D patent/SE199837C1/sv unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1064496A (en) | Preparation of a new cincamine salt and compound thus obtained | |
| US3732340A (en) | N',o-propylene phosphoric acid ester diamides | |
| KR20010102082A (ko) | 항바이러스제로서의 포스포르아미데이트, 및 (1ｒ, 시스)-4-(6-아미노-9ｈ-푸린-9-일)-2-시클로펜텐-1-메탄올의 모노-, 디-, 및 트리-포스페이트 에스테르 | |
| KR840000702B1 (ko) | 빈카민 사카리네이트의 제조방법 | |
| SE199837C1 (enrdf_load_stackoverflow) | ||
| US2608507A (en) | Dialkyl sulfamyl benzoic acids | |
| US3925393A (en) | Novel salts of vincanol | |
| SU1384202A3 (ru) | Способ получени замещенных тиазолидиниловых эфиров фосфорной кислоты | |
| US3764694A (en) | Anticoccidiosis method and compositions | |
| Suter et al. | The Sulfonation of Methallyl Chloride. Mobility of the Olefinic Linkage in Unsaturated Sulfonic Acids | |
| US3644531A (en) | 2-propynylsulfonium salts | |
| US2407686A (en) | Sulphanilamide derivatives and method of preparing same | |
| US2857395A (en) | Derivatives of alpha-n-(beta-dialkylamino alkyl)-amino-phenyl acetic acid esters | |
| US3076800A (en) | Jj-lactams unsubstituted at the nitrogen | |
| US2789997A (en) | Glycine ester salts of cyclohexylsulfamic acid | |
| Clarke et al. | BENZENESULFONYLGUANIDINES1 | |
| PT93675B (pt) | Processo para a preparacao de derivados de acidos aminodicarboxilicos insaturados, contendo fosforo | |
| US2309870A (en) | Derivatives of p-aminobenzene-sulphonamide | |
| US1280120A (en) | Arsenical compound. | |
| US2654752A (en) | Beta-4-morpholinoethyl-benzoate salt of penicillin | |
| US3453269A (en) | Novel chlorpromazine salts | |
| SU452195A1 (ru) | Способ получени дийодметилата ди-( -диэтиламинопропилового эфира) -труксилловой кислоты | |
| US2603641A (en) | Sulfonamide choline compounds and process | |
| ES2340666T3 (es) | Sales de derivados de guanidina y composiciones farmaceuticas obtenidas a partir de ellas. | |
| US3061511A (en) | Thiolpropionate compositions |