SE0700930L - Assay device for liquid samples - Google Patents

Assay device for liquid samples

Info

Publication number
SE0700930L
SE0700930L SE0700930A SE0700930A SE0700930L SE 0700930 L SE0700930 L SE 0700930L SE 0700930 A SE0700930 A SE 0700930A SE 0700930 A SE0700930 A SE 0700930A SE 0700930 L SE0700930 L SE 0700930L
Authority
SE
Sweden
Prior art keywords
liquid
sink
receiving
flow paths
liquid samples
Prior art date
Application number
SE0700930A
Other languages
Swedish (sv)
Other versions
SE529978C2 (en
Inventor
David Bergman
Pierre Kreueger
David Roennholm
Original Assignee
Aamic Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aamic Ab filed Critical Aamic Ab
Priority to SE0700930A priority Critical patent/SE529978C2/en
Publication of SE0700930L publication Critical patent/SE0700930L/en
Publication of SE529978C2 publication Critical patent/SE529978C2/en
Priority to PCT/SE2008/050424 priority patent/WO2008127191A1/en
Priority to CN200880012452.4A priority patent/CN101678355B/en
Priority to JP2010504015A priority patent/JP5425757B2/en
Priority to EP08741914.9A priority patent/EP2134472A4/en
Priority to CA2683920A priority patent/CA2683920C/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0017Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K2099/0082Microvalves adapted for a particular use
    • F16K2099/0084Chemistry or biology, e.g. "lab-on-a-chip" technology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

There is disclosed a device for handling liquid samples, said device comprising: a) projections substantially perpendicular to the surface of said device, said projections having a height, diameter and a distance between the projections capable of generating capillary flow, lateral to said surface, of a fluid, b) at least one zone for receiving a sample, c) at least one sink with a capacity of receiving said liquid, said at least one sink exerting at least two different capillary forces on said liquid, d) at least two flow paths connecting said at least one zone for receiving a sample and said at least one sink, said flow paths exerting at least two different capillary forces on said liquid, e) at least one connection between said at least two flow paths.
SE0700930A 2007-04-16 2007-04-16 Analysis device for liquid samples, e.g. patient samples, includes flow paths between sample receiving and holding areas capable of exerting different capillary forces SE529978C2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE0700930A SE529978C2 (en) 2007-04-16 2007-04-16 Analysis device for liquid samples, e.g. patient samples, includes flow paths between sample receiving and holding areas capable of exerting different capillary forces
PCT/SE2008/050424 WO2008127191A1 (en) 2007-04-16 2008-04-15 Device for handling liquid samples
CN200880012452.4A CN101678355B (en) 2007-04-16 2008-04-15 Device for handling liquid samples
JP2010504015A JP5425757B2 (en) 2007-04-16 2008-04-15 Apparatus for processing liquid samples
EP08741914.9A EP2134472A4 (en) 2007-04-16 2008-04-15 Device for handling liquid samples
CA2683920A CA2683920C (en) 2007-04-16 2008-04-15 Device for handling liquid samples

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0700930A SE529978C2 (en) 2007-04-16 2007-04-16 Analysis device for liquid samples, e.g. patient samples, includes flow paths between sample receiving and holding areas capable of exerting different capillary forces

Publications (2)

Publication Number Publication Date
SE0700930L true SE0700930L (en) 2008-01-22
SE529978C2 SE529978C2 (en) 2008-01-22

Family

ID=38935813

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0700930A SE529978C2 (en) 2007-04-16 2007-04-16 Analysis device for liquid samples, e.g. patient samples, includes flow paths between sample receiving and holding areas capable of exerting different capillary forces

Country Status (6)

Country Link
EP (1) EP2134472A4 (en)
JP (1) JP5425757B2 (en)
CN (1) CN101678355B (en)
CA (1) CA2683920C (en)
SE (1) SE529978C2 (en)
WO (1) WO2008127191A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9216413B2 (en) 2009-07-07 2015-12-22 Boehringer Ingelheim Microparts Gmbh Plasma separation reservoir
JP6133063B2 (en) * 2012-01-20 2017-05-24 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドOrtho−Clinical Diagnostics, Inc. Assay device with uniform flow around corners
US20130210036A1 (en) * 2012-01-20 2013-08-15 Ortho-Clinical Diagnostics, Inc. Controlling Fluid Flow Through An Assay Device
JP6278772B2 (en) * 2014-03-19 2018-02-14 テルモ株式会社 Blood glucose measurement chip
WO2016084381A1 (en) * 2014-11-28 2016-06-02 東洋製罐グループホールディングス株式会社 Micro liquid transfer structure and analysis device
CN107219170B (en) * 2017-07-24 2023-09-19 苏州鼎实医疗科技有限公司 Reagent tablet
EP4213990A1 (en) * 2020-09-17 2023-07-26 Katholieke Universiteit Leuven Activation and pressure balancing mechanism

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0610900A (en) * 1992-04-27 1994-01-21 Canon Inc Method and device for moving liquid and measuring device utilizing these method and device
US6156270A (en) * 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
JP3213566B2 (en) * 1996-04-26 2001-10-02 アークレイ株式会社 Sample analysis tool, sample analysis method and sample analyzer using the same
EP1125129A1 (en) * 1998-10-13 2001-08-22 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6571651B1 (en) * 2000-03-27 2003-06-03 Lifescan, Inc. Method of preventing short sampling of a capillary or wicking fill device
SE0201738D0 (en) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
KR100444751B1 (en) * 2002-11-11 2004-08-16 한국전자통신연구원 Device of Controlling Fluid using Surface Tension
US20060043284A1 (en) * 2002-11-29 2006-03-02 Nec Corporation Micro chip, liquid feeding method using the micro chip, and mass analyzing system
DE10302720A1 (en) * 2003-01-23 2004-08-05 Steag Microparts Gmbh Microfluidic switch for stopping the flow of fluid during a time interval
EP1525916A1 (en) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Flow triggering device
EP1525919A1 (en) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Flow triggering device
CN1238713C (en) * 2003-11-01 2006-01-25 浙江大学 Integrated minityped magnetic pump model capillary electrophoresis chip
GB2410086A (en) * 2004-01-14 2005-07-20 British Biocell Internat Ltd Assay devices having flow block(s) to determine flow of liquids
WO2005075975A1 (en) * 2004-02-06 2005-08-18 Nec Corporation Control structure, separating device, gradient forming device, and micro chip using the same
SE0400662D0 (en) * 2004-03-24 2004-03-24 Aamic Ab Assay device and method
SE527036C2 (en) * 2004-06-02 2005-12-13 Aamic Ab Controlled flow analysis device and corresponding procedure
US7682817B2 (en) * 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
EP1853911A1 (en) * 2005-02-25 2007-11-14 Inverness Medical Switzerland GmbH Fluidic gating device
JPWO2006098370A1 (en) * 2005-03-16 2008-08-28 日本電気株式会社 DELAY CIRCUIT, MICROCHIP HAVING ADJUSTING MECHANISM FOR EFFECTIVE PASSING TIME OF PATH, AND METHOD FOR MANUFACTURING THE SAME

Also Published As

Publication number Publication date
CN101678355A (en) 2010-03-24
JP2010525319A (en) 2010-07-22
EP2134472A1 (en) 2009-12-23
CA2683920A1 (en) 2008-10-23
CN101678355B (en) 2012-11-14
WO2008127191A1 (en) 2008-10-23
SE529978C2 (en) 2008-01-22
CA2683920C (en) 2016-05-31
JP5425757B2 (en) 2014-02-26
EP2134472A4 (en) 2014-10-01

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