SE0201977D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE0201977D0 SE0201977D0 SE0201977A SE0201977A SE0201977D0 SE 0201977 D0 SE0201977 D0 SE 0201977D0 SE 0201977 A SE0201977 A SE 0201977A SE 0201977 A SE0201977 A SE 0201977A SE 0201977 D0 SE0201977 D0 SE 0201977D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- compounds
- diseases associated
- inhibitors
- cathepsin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyrane Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Saccharide Compounds (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201977A SE0201977D0 (sv) | 2002-06-24 | 2002-06-24 | Novel compounds |
PT03761003T PT1532124E (pt) | 2002-06-24 | 2003-06-23 | Utilização de derivados de nitrilo como medicamento |
EP03761003A EP1532124B1 (en) | 2002-06-24 | 2003-06-23 | Use of nitrile derivatives as medicament. |
SI200330491T SI1532124T1 (sl) | 2002-06-24 | 2003-06-23 | Uporaba nitrilnih derivatov kot zdravila |
PCT/SE2003/001080 WO2004000825A1 (en) | 2002-06-24 | 2003-06-23 | Novel compounds |
DE60306934T DE60306934T2 (de) | 2002-06-24 | 2003-06-23 | Verwendung von Nitrilenverbindungen als Arzneimittel |
AT03761003T ATE333451T1 (de) | 2002-06-24 | 2003-06-23 | Verwendung von nitrilenverbindungen als arztneimittel |
AU2003243097A AU2003243097A1 (en) | 2002-06-24 | 2003-06-23 | Novel compounds |
US10/518,818 US20050245522A1 (en) | 2002-06-24 | 2003-06-23 | Novel compounds |
DK03761003T DK1532124T3 (da) | 2002-06-24 | 2003-06-23 | Anvendelse af nitriderivater som medikament |
JP2004515330A JP2005533805A (ja) | 2002-06-24 | 2003-06-23 | 新規化合物 |
ES03761003T ES2268423T3 (es) | 2002-06-24 | 2003-06-23 | Uso de derivados de nitrilo como medicamento. |
CY20061101476T CY1107342T1 (el) | 2002-06-24 | 2006-10-13 | Χρηση παραγωγων νιτριλιου ως φαρμακο |
US12/132,080 US20080234274A1 (en) | 2002-06-24 | 2008-06-03 | Novel Compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201977A SE0201977D0 (sv) | 2002-06-24 | 2002-06-24 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0201977D0 true SE0201977D0 (sv) | 2002-06-24 |
Family
ID=20288335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0201977A SE0201977D0 (sv) | 2002-06-24 | 2002-06-24 | Novel compounds |
Country Status (12)
Country | Link |
---|---|
US (2) | US20050245522A1 (xx) |
EP (1) | EP1532124B1 (xx) |
JP (1) | JP2005533805A (xx) |
AT (1) | ATE333451T1 (xx) |
AU (1) | AU2003243097A1 (xx) |
CY (1) | CY1107342T1 (xx) |
DE (1) | DE60306934T2 (xx) |
DK (1) | DK1532124T3 (xx) |
ES (1) | ES2268423T3 (xx) |
PT (1) | PT1532124E (xx) |
SE (1) | SE0201977D0 (xx) |
WO (1) | WO2004000825A1 (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0201977D0 (sv) * | 2002-06-24 | 2002-06-24 | Astrazeneca Ab | Novel compounds |
US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
CN100393700C (zh) * | 2003-06-30 | 2008-06-11 | 麦克弗罗斯特(加拿大)公司 | 组织蛋白酶半胱氨酸蛋白酶抑制剂 |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
CA2635437C (en) | 2006-02-11 | 2020-01-28 | Genetronics, Inc. | Device and method for single-needle in vivo electroporation |
CN101453993A (zh) | 2006-04-03 | 2009-06-10 | 伊萨·奥迪迪 | 含有机溶胶涂层的受控释放递送物件 |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
US20080207683A1 (en) * | 2007-02-15 | 2008-08-28 | Darin Allen | Biaryl-substituted tetrahydro-pyrazolo-pyridine modulators of cathepsin s |
US20090099157A1 (en) * | 2007-02-15 | 2009-04-16 | Ameriks Michael K | Tetrahydro-pyrazolo-pyridine thioether modulators of cathepsin s |
US20090118274A1 (en) * | 2007-02-15 | 2009-05-07 | Darin Allen | Monocyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s |
US20080269241A1 (en) * | 2007-02-15 | 2008-10-30 | Darin Allen | Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine modulators of cathepsin s |
US20080200454A1 (en) * | 2007-02-15 | 2008-08-21 | Ameriks Michael K | Carbon-linked tetrahydro-pyrazolo-pyridine modulators of cathepsin s |
WO2009001127A1 (en) * | 2007-06-26 | 2008-12-31 | Astrazeneca Ab | Cyanocyclopropylcarboxamides as cathepsin inhibitors |
WO2009001128A1 (en) * | 2007-06-26 | 2008-12-31 | Astrazeneca Ab | 1,2-cycl0hexane dicarboxamides as cathepsin inhibitors |
JP2010531344A (ja) * | 2007-06-26 | 2010-09-24 | アストラゼネカ アクチボラグ | カテプシンk阻害剤としての1−シアノシクロプロピル誘導体 |
US7893099B2 (en) * | 2009-06-11 | 2011-02-22 | Hoffman-La Roche Inc. | Cyclopentane derivatives |
CH704051B1 (fr) * | 2010-11-04 | 2013-10-15 | Nivarox Sa | Echappement synchrone pour mécanisme d'horlogerie. |
WO2020201572A1 (en) | 2019-04-05 | 2020-10-08 | Université De Bretagne Occidentale | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2368148A1 (en) * | 1999-03-15 | 2000-09-21 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions as protease inhibitors |
US6313117B1 (en) * | 1999-07-30 | 2001-11-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Succinate derivative compounds useful as cysteine protease inhibitors |
US20010041700A1 (en) * | 1999-07-30 | 2001-11-15 | Younes Bekkali | Novel succinate derivative compounds useful as cysteine protease inhibitors |
SE0201977D0 (sv) * | 2002-06-24 | 2002-06-24 | Astrazeneca Ab | Novel compounds |
-
2002
- 2002-06-24 SE SE0201977A patent/SE0201977D0/xx unknown
-
2003
- 2003-06-23 EP EP03761003A patent/EP1532124B1/en not_active Expired - Lifetime
- 2003-06-23 AT AT03761003T patent/ATE333451T1/de not_active IP Right Cessation
- 2003-06-23 DK DK03761003T patent/DK1532124T3/da active
- 2003-06-23 WO PCT/SE2003/001080 patent/WO2004000825A1/en active IP Right Grant
- 2003-06-23 DE DE60306934T patent/DE60306934T2/de not_active Expired - Lifetime
- 2003-06-23 PT PT03761003T patent/PT1532124E/pt unknown
- 2003-06-23 JP JP2004515330A patent/JP2005533805A/ja active Pending
- 2003-06-23 ES ES03761003T patent/ES2268423T3/es not_active Expired - Lifetime
- 2003-06-23 US US10/518,818 patent/US20050245522A1/en not_active Abandoned
- 2003-06-23 AU AU2003243097A patent/AU2003243097A1/en not_active Abandoned
-
2006
- 2006-10-13 CY CY20061101476T patent/CY1107342T1/el unknown
-
2008
- 2008-06-03 US US12/132,080 patent/US20080234274A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60306934D1 (de) | 2006-08-31 |
ATE333451T1 (de) | 2006-08-15 |
EP1532124B1 (en) | 2006-07-19 |
DK1532124T3 (da) | 2006-10-30 |
CY1107342T1 (el) | 2012-12-19 |
US20050245522A1 (en) | 2005-11-03 |
US20080234274A1 (en) | 2008-09-25 |
PT1532124E (pt) | 2006-11-30 |
EP1532124A1 (en) | 2005-05-25 |
AU2003243097A1 (en) | 2004-01-06 |
JP2005533805A (ja) | 2005-11-10 |
DE60306934T2 (de) | 2007-02-15 |
WO2004000825A1 (en) | 2003-12-31 |
ES2268423T3 (es) | 2007-03-16 |
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