SE0201193D0 - Novel use - Google Patents

Novel use

Info

Publication number
SE0201193D0
SE0201193D0 SE0201193A SE0201193A SE0201193D0 SE 0201193 D0 SE0201193 D0 SE 0201193D0 SE 0201193 A SE0201193 A SE 0201193A SE 0201193 A SE0201193 A SE 0201193A SE 0201193 D0 SE0201193 D0 SE 0201193D0
Authority
SE
Sweden
Prior art keywords
prophylaxis
formula
treatment
pharmaceutically acceptable
disclosed
Prior art date
Application number
SE0201193A
Other languages
Swedish (sv)
Inventor
Sverker Hanson
Gunnar Nordvall
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0201193A priority Critical patent/SE0201193D0/en
Publication of SE0201193D0 publication Critical patent/SE0201193D0/en
Priority to ARP030101208A priority patent/AR039385A1/en
Priority to TW092108547A priority patent/TWI335918B/en
Priority to UA20040907781A priority patent/UA78986C2/en
Priority to ES03721211T priority patent/ES2373224T3/en
Priority to US10/511,537 priority patent/US7425560B2/en
Priority to RU2004128389/04A priority patent/RU2323219C2/en
Priority to CA2752132A priority patent/CA2752132A1/en
Priority to CNB038083558A priority patent/CN100379737C/en
Priority to NZ535406A priority patent/NZ535406A/en
Priority to KR1020117027657A priority patent/KR20110132635A/en
Priority to AU2003224548A priority patent/AU2003224548B2/en
Priority to PCT/SE2003/000617 priority patent/WO2003089430A1/en
Priority to CN2007101082174A priority patent/CN101062037B/en
Priority to EP10170768A priority patent/EP2332541A1/en
Priority to KR1020117007364A priority patent/KR20110036871A/en
Priority to PL03373197A priority patent/PL373197A1/en
Priority to AT03721211T priority patent/ATE529428T1/en
Priority to JP2003586151A priority patent/JP4649112B2/en
Priority to CA2480452A priority patent/CA2480452C/en
Priority to KR1020047016709A priority patent/KR101064092B1/en
Priority to EP03721211A priority patent/EP1499613B1/en
Priority to BR0309012-4A priority patent/BR0309012A/en
Priority to MXPA04010055A priority patent/MXPA04010055A/en
Priority to MYPI20031447A priority patent/MY157949A/en
Priority to IL16431504A priority patent/IL164315A0/en
Priority to ZA200407815A priority patent/ZA200407815B/en
Priority to IS7509A priority patent/IS7509A/en
Priority to NO20044998A priority patent/NO331002B1/en
Priority to HK05104394.9A priority patent/HK1071568A1/en
Priority to RU2007142328/04A priority patent/RU2007142328A/en
Priority to HK08104395.5A priority patent/HK1114500A1/en
Priority to US12/185,158 priority patent/US8236951B2/en
Priority to AU2010200345A priority patent/AU2010200345B2/en
Priority to JP2010049998A priority patent/JP2010138190A/en
Priority to NO20100939A priority patent/NO20100939L/en

Links

Abstract

There is disclosed the use of a compound of formula (Ia) or (Ib)wherein R<1>, R<2>, R<3>, R<4>, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of the enzyme myeloperoxidase (MPO) is beneficial. Certain novel compounds of formula (Ia) or (Ib) and pharmaceutically acceptable salts thereof are disclosed, together with processes for their preparation. The compounds of formulae (Ia) and (Ib) are MPO inhibitors and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders.
SE0201193A 2002-04-19 2002-04-19 Novel use SE0201193D0 (en)

Priority Applications (36)

Application Number Priority Date Filing Date Title
SE0201193A SE0201193D0 (en) 2002-04-19 2002-04-19 Novel use
ARP030101208A AR039385A1 (en) 2002-04-19 2003-04-07 THIOXANTINE DERIVATIVES AS INHIBITORS OF MIELOPEROXIDASA
TW092108547A TWI335918B (en) 2002-04-19 2003-04-14 Novel thioxanthine derivatives and medical use thereof
MXPA04010055A MXPA04010055A (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors.
PL03373197A PL373197A1 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
KR1020047016709A KR101064092B1 (en) 2002-04-19 2003-04-15 Thioxanthin Derivatives as Mieloperoxidase Inhibitors
US10/511,537 US7425560B2 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
RU2004128389/04A RU2323219C2 (en) 2002-04-19 2003-04-15 Derivatives of thioxanthine as myeloperoxidase inhibitors
CA2752132A CA2752132A1 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
CNB038083558A CN100379737C (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
NZ535406A NZ535406A (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
KR1020117027657A KR20110132635A (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
AU2003224548A AU2003224548B2 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
PCT/SE2003/000617 WO2003089430A1 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
CN2007101082174A CN101062037B (en) 2002-04-19 2003-04-15 Process for their preparation of thioxanthine derivatives, their use
EP10170768A EP2332541A1 (en) 2002-04-19 2003-04-15 Use of thioxanthine derivatives as MPO inhibitors
KR1020117007364A KR20110036871A (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
UA20040907781A UA78986C2 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives, process for their preparation (variants), their use and composition containing them
AT03721211T ATE529428T1 (en) 2002-04-19 2003-04-15 THIOXANTHINE DERIVATIVES AS MYELOPEROXIDASINE INHIBITORS
JP2003586151A JP4649112B2 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
CA2480452A CA2480452C (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
ES03721211T ES2373224T3 (en) 2002-04-19 2003-04-15 THIOXANTINE DERIVATIVES AS INHIBITORS OF MIELOPEROXIDASA.
EP03721211A EP1499613B1 (en) 2002-04-19 2003-04-15 Thioxanthine derivatives as myeloperoxidase inhibitors
BR0309012-4A BR0309012A (en) 2002-04-19 2003-04-15 Use of a compound, pharmaceutical formulation, compound, pharmaceutical composition, and process for preparing a compound
MYPI20031447A MY157949A (en) 2002-04-19 2003-04-17 Thioxanthine derivatives as myeloperoxidase inhibitors
IL16431504A IL164315A0 (en) 2002-04-19 2004-09-27 Thioxanthine derivatives as myeloperoxidase inhibitors
ZA200407815A ZA200407815B (en) 2002-04-19 2004-09-28 Thioxanthine derivatives as myeloperoxidase inhibitors.
IS7509A IS7509A (en) 2002-04-19 2004-10-15 Thioxanthin derivatives as marrow peroxidase inhibitors
NO20044998A NO331002B1 (en) 2002-04-19 2004-11-17 Thioxanthine derivatives and pharmaceutical preparations with thioxanthine derivatives
HK05104394.9A HK1071568A1 (en) 2002-04-19 2005-05-25 Thioxanthine derivatives as myeloperoxidase inhibitors
RU2007142328/04A RU2007142328A (en) 2002-04-19 2007-11-16 Thioxanthine derivatives as myeloperoxidase inhibitors
HK08104395.5A HK1114500A1 (en) 2002-04-19 2008-04-18 Method for producing thioxanthine derivatives as myeloperoxidase inhibitors, and use of said thioxanthine derivatives
US12/185,158 US8236951B2 (en) 2002-04-19 2008-08-04 Thioxanthine derivatives as myeloperoxidase inhibitors
AU2010200345A AU2010200345B2 (en) 2002-04-19 2010-01-29 Thioxanthine derivatives as myeloperoxidase inhibitors
JP2010049998A JP2010138190A (en) 2002-04-19 2010-03-08 Thioxanthine derivative as myeloperoxidase inhibitor
NO20100939A NO20100939L (en) 2002-04-19 2010-06-28 Thioxanthine derivatives as myeloperoxidase inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0201193A SE0201193D0 (en) 2002-04-19 2002-04-19 Novel use

Publications (1)

Publication Number Publication Date
SE0201193D0 true SE0201193D0 (en) 2002-04-19

Family

ID=20287630

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0201193A SE0201193D0 (en) 2002-04-19 2002-04-19 Novel use

Country Status (4)

Country Link
CN (1) CN101062037B (en)
SE (1) SE0201193D0 (en)
UA (1) UA78986C2 (en)
ZA (1) ZA200407815B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202000086PA (en) * 2017-07-17 2020-02-27 Astrazeneca Ab Mpo inhibitors for use in medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines

Also Published As

Publication number Publication date
CN101062037A (en) 2007-10-31
UA78986C2 (en) 2007-05-10
ZA200407815B (en) 2005-10-04
CN101062037B (en) 2011-05-25

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