SE0402972D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0402972D0
SE0402972D0 SE0402972A SE0402972A SE0402972D0 SE 0402972 D0 SE0402972 D0 SE 0402972D0 SE 0402972 A SE0402972 A SE 0402972A SE 0402972 A SE0402972 A SE 0402972A SE 0402972 D0 SE0402972 D0 SE 0402972D0
Authority
SE
Sweden
Prior art keywords
sup
novel compounds
disorders
compounds
prophylaxis
Prior art date
Application number
SE0402972A
Other languages
Swedish (sv)
Inventor
Yvonne Lo-Alfredsson
Anna-Karin Tiden
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0402972A priority Critical patent/SE0402972D0/en
Publication of SE0402972D0 publication Critical patent/SE0402972D0/en
Priority to MYPI20055659A priority patent/MY140748A/en
Priority to BRPI0518846-6A priority patent/BRPI0518846B1/en
Priority to CA2591314A priority patent/CA2591314C/en
Priority to KR1020137005332A priority patent/KR101412939B1/en
Priority to PT05812036T priority patent/PT1824855E/en
Priority to JP2007544307A priority patent/JP5028270B2/en
Priority to CN2005800419194A priority patent/CN101072778B/en
Priority to SA05260385A priority patent/SA05260385B1/en
Priority to ARP050105071A priority patent/AR051698A1/en
Priority to RS20120426A priority patent/RS52490B/en
Priority to MX2007006497A priority patent/MX2007006497A/en
Priority to MEP-2012-109A priority patent/ME01486B/en
Priority to AU2005312388A priority patent/AU2005312388B2/en
Priority to ES05812036T priority patent/ES2390888T3/en
Priority to RU2010139806/04A priority patent/RU2577858C2/en
Priority to DK05812036.1T priority patent/DK1824855T3/en
Priority to PCT/SE2005/001835 priority patent/WO2006062465A1/en
Priority to NZ555046A priority patent/NZ555046A/en
Priority to UY29246A priority patent/UY29246A1/en
Priority to KR1020077012654A priority patent/KR101412786B1/en
Priority to KR1020137033109A priority patent/KR101557715B1/en
Priority to UAA200705136A priority patent/UA89968C2/en
Priority to PL05812036T priority patent/PL1824855T3/en
Priority to US11/720,913 priority patent/US7829707B2/en
Priority to RU2007119307/04A priority patent/RU2409578C2/en
Priority to EP05812036A priority patent/EP1824855B1/en
Priority to SI200631433T priority patent/SI1824855T1/en
Priority to TW094143007A priority patent/TWI365189B/en
Priority to NO20072399A priority patent/NO20072399L/en
Priority to IL183182A priority patent/IL183182A/en
Priority to ZA200705000A priority patent/ZA200705000B/en
Priority to HK08105257.9A priority patent/HK1110859A1/en
Priority to US12/938,490 priority patent/US8859568B2/en
Priority to HRP20120781TT priority patent/HRP20120781T1/en
Priority to CY20121100939T priority patent/CY1113209T1/en
Priority to US14/487,009 priority patent/US9580429B2/en
Priority to ARP160100534A priority patent/AR103818A2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

There are disclosed novel compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>12</SUP>, L, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders, cardiovascular disorders and respiratory disorders.
SE0402972A 2004-12-06 2004-12-06 Novel compounds SE0402972D0 (en)

Priority Applications (38)

Application Number Priority Date Filing Date Title
SE0402972A SE0402972D0 (en) 2004-12-06 2004-12-06 Novel compounds
MYPI20055659A MY140748A (en) 2004-12-06 2005-12-02 Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
SI200631433T SI1824855T1 (en) 2004-12-06 2005-12-05 Novel pyrrolo ?á3, 2-d?åpyrimidin-4-one derivatives and their use in therapy
KR1020137005332A KR101412939B1 (en) 2004-12-06 2005-12-05 Novel pyrrolo[3,2-d]pyrimidin-4-one derivatives and their use in therapy
KR1020077012654A KR101412786B1 (en) 2004-12-06 2005-12-05 Novel pyrrolo[3,2-d]pyrimidin-4-one derivatives and their use in therapy
NZ555046A NZ555046A (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d] pyrimidin-4-one derivatives and their use in therapy
CA2591314A CA2591314C (en) 2004-12-06 2005-12-05 Novel pyrrolo[3,2-d]pyrimidin-4-one derivatives and their use in therapy
JP2007544307A JP5028270B2 (en) 2004-12-06 2005-12-05 Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
CN2005800419194A CN101072778B (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d] pyrimidin-4-one derivatives and their use in therapy
SA05260385A SA05260385B1 (en) 2004-12-06 2005-12-05 Novel pyrrolo[3.2-d] pyrimidin-4-one derivatives and their use in therapy
ARP050105071A AR051698A1 (en) 2004-12-06 2005-12-05 PIRROLO DERIVATIVES [3,2-D] PIRIMIDIN-4-ONA AS MYELOPEROXIDASE INHIBITORS
RS20120426A RS52490B (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d]pyrimidin-4-one derivatives and their use in therapy
MX2007006497A MX2007006497A (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d] pyrimidin-4-one derivatives and their use in therapy.
MEP-2012-109A ME01486B (en) 2004-12-06 2005-12-05 Novel pyrrolo (3, 2-d)pyrimidin-4-one derivatives and their use in therapy
AU2005312388A AU2005312388B2 (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d] pyrimidin-4-one derivatives and their use in therapy
ES05812036T ES2390888T3 (en) 2004-12-06 2005-12-05 New derivatives of pyrrolo [3,2-d] pyrimidin-4-one and its use in therapy
RU2010139806/04A RU2577858C2 (en) 2004-12-06 2005-12-05 NEW PYRROLO[3,2-d]PYRIMIDIN-4-ONE DERIVATIVES AND USING THEM IN THERAPY
DK05812036.1T DK1824855T3 (en) 2004-12-06 2005-12-05 New pyrrolo (3,2-d) pyrimidine-4-derivatives and their uses for treatment
PCT/SE2005/001835 WO2006062465A1 (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d] pyrimidin-4-one derivatives and their use in therapy
BRPI0518846-6A BRPI0518846B1 (en) 2004-12-06 2005-12-05 Compound, pharmaceutical composition and use of the compound
PT05812036T PT1824855E (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d]pyrimidin-4-one derivatives and their use in therapy
UY29246A UY29246A1 (en) 2004-12-06 2005-12-05 NEW COMPOUNDS
KR1020137033109A KR101557715B1 (en) 2004-12-06 2005-12-05 Novel pyrrolo[3,2-d]pyrimidin-4-one derivatives and their use in therapy
UAA200705136A UA89968C2 (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d]pyrimidin-4-one derivatives and their use in therapy
PL05812036T PL1824855T3 (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d]pyrimidin-4-one derivatives and their use in therapy
US11/720,913 US7829707B2 (en) 2004-12-06 2005-12-05 Pyrrolo [3,2-d]pyrimidin-4-one derivatives and their use in therapy
RU2007119307/04A RU2409578C2 (en) 2004-12-06 2005-12-05 1-(2-ISOPROPOXYETHYL)-2-THIOXO-1,2,3,5-TETRAHYDRO-PYRROLO[3,2-d]PYRIMIDIN-4-ONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
EP05812036A EP1824855B1 (en) 2004-12-06 2005-12-05 Novel pyrrolo [3, 2-d]pyrimidin-4-one derivatives and their use in therapy
TW094143007A TWI365189B (en) 2004-12-06 2005-12-06 Novel pyrrolo[3,2-d]pyrimidin-4-one derivatives
NO20072399A NO20072399L (en) 2004-12-06 2007-05-10 New pyrrolo [3,2-d] pyrimidin-4-o derivatives and their use in therapy
IL183182A IL183182A (en) 2004-12-06 2007-05-14 Pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
ZA200705000A ZA200705000B (en) 2004-12-06 2007-06-01 Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
HK08105257.9A HK1110859A1 (en) 2004-12-06 2008-05-13 Novel pyrrolo [3, 2-d] pyrimidin-4-one derivatives and their use in therapy
US12/938,490 US8859568B2 (en) 2004-12-06 2010-11-03 Pyrrolo[3,2-D]pyrimidin-4-one derivatives and their use in therapy
HRP20120781TT HRP20120781T1 (en) 2004-12-06 2012-10-02 Novel pyrrolo [3, 2-d]pyrimidin-4-one derivatives and their use in therapy
CY20121100939T CY1113209T1 (en) 2004-12-06 2012-10-10 NEW PYROLOL [3,2-D] PYRIMIDIN-4-ONE PRODUCERS AND THEIR USE IN THERAPY
US14/487,009 US9580429B2 (en) 2004-12-06 2014-09-15 Pyrrolo[3,2-D]pyrimidin-4-one derivatives and their use in therapy
ARP160100534A AR103818A2 (en) 2004-12-06 2016-03-01 MYELOPEROXIDASE INHIBITORS PIRROLOPIRIMIDINE DERIVATIVES (MPO)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0402972A SE0402972D0 (en) 2004-12-06 2004-12-06 Novel compounds

Publications (1)

Publication Number Publication Date
SE0402972D0 true SE0402972D0 (en) 2004-12-06

Family

ID=33550599

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0402972A SE0402972D0 (en) 2004-12-06 2004-12-06 Novel compounds

Country Status (3)

Country Link
AR (1) AR103818A2 (en)
SE (1) SE0402972D0 (en)
ZA (1) ZA200705000B (en)

Also Published As

Publication number Publication date
AR103818A2 (en) 2017-06-07
ZA200705000B (en) 2008-09-25

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