SE0103313D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE0103313D0 SE0103313D0 SE0103313A SE0103313A SE0103313D0 SE 0103313 D0 SE0103313 D0 SE 0103313D0 SE 0103313 A SE0103313 A SE 0103313A SE 0103313 A SE0103313 A SE 0103313A SE 0103313 D0 SE0103313 D0 SE 0103313D0
- Authority
- SE
- Sweden
- Prior art keywords
- sub
- sup
- ring
- novel compounds
- phenyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 125000002346 iodo group Chemical group I* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000001425 triazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0103313A SE0103313D0 (sv) | 2001-10-03 | 2001-10-03 | Novel compounds |
| ARP020103670A AR036649A1 (es) | 2001-10-03 | 2002-09-27 | Derivados de diarilmetilen piperidina, uso de estos derivados para la manufactura de medicamentos y composicion farmaceutica |
| CA002460168A CA2460168A1 (en) | 2001-10-03 | 2002-10-02 | 4[piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
| IL16088902A IL160889A0 (en) | 2001-10-03 | 2002-10-02 | 4 [piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
| KR10-2004-7004780A KR20040039469A (ko) | 2001-10-03 | 2002-10-02 | 4[피페리딘-4-일리덴-(3-카르바모일페닐)메틸]벤즈아미드유도체 및 통증, 척추 손상 또는 위장 장애 치료에있어서의 이들의 용도 |
| BR0212959-0A BR0212959A (pt) | 2001-10-03 | 2002-10-02 | Composto, uso do mesmo, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrointestinais e de lesões espinhais |
| CNA028195825A CN1692100A (zh) | 2001-10-03 | 2002-10-02 | 4－[哌啶－4－亚基－(3－氨基甲酰苯基)甲基]苯甲酰胺衍生物及其在治疗疼痛、脊椎损伤或胃肠疾病方面的应用 |
| MXPA04003056A MXPA04003056A (es) | 2001-10-03 | 2002-10-02 | Derivados de 4?piperidin-4-iliden-(3-carbamoilfenil)metil? benzamida y su uso para tratamiento de dolor, lesiones espinales o transtornos gastrointestinales. |
| JP2003532465A JP2005505583A (ja) | 2001-10-03 | 2002-10-02 | ４［ピペリジン−４−イリデン−（３−カルバモイルフェニル）メチル］ベンズアミド誘導体、および疼痛、脊髄損傷または胃腸疾患の治療のためのその使用 |
| PL02368804A PL368804A1 (en) | 2001-10-03 | 2002-10-02 | 4(piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
| PCT/SE2002/001804 WO2003029215A1 (en) | 2001-10-03 | 2002-10-02 | 4[piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
| RU2004107854/04A RU2004107854A (ru) | 2001-10-03 | 2002-10-02 | Производные 4[пиперидин-4-илиден-(3-карбомоилфенил)метил]бензамида и их применение для лечении боли, спинальных повреждений или желудочно-кишечных расстройств |
| HU0401915A HUP0401915A2 (hu) | 2001-10-03 | 2002-10-02 | 4-[4-Piperidinilidén-(3-karbamoil-fenil)-metil]-benzamid-származékok és alkalmazásuk fájdalom, gerincsérülések vagy gasztrointesztinális rendellenességek kezelésére és ezeket tartalmazó gyógyszerkészítmények |
| EP02775640A EP1440060A1 (en) | 2001-10-03 | 2002-10-02 | 4(piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
| US10/491,263 US7205317B2 (en) | 2001-10-03 | 2002-10-02 | 4[piperidin-4-yliden-(3-carbamoylpheny)methyl]benzamide derivatives and their use for the treatment of pain spinal injuries or gastrointestinal disorders |
| ZA200402514A ZA200402514B (en) | 2001-10-03 | 2004-03-30 | 4[Piperidin-4-yliden-(3-carbamoylphenyl)methyl]benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders. |
| CO04030712A CO5580822A2 (es) | 2001-10-03 | 2004-03-31 | Derivados de 4[piperidin-4-iliden-(3-carbamoilfenil)metil] benzamida y sus usos para el tratamiento del dolor, las lesiones en la columna vertebral o desordenes gastrointes- tinales |
| IS7203A IS7203A (is) | 2001-10-03 | 2004-03-31 | 4[píperidín-4-ýliden-(3-karbamólýlfenýl)metýl]bensamíðafleiður og notkun þeirra til að meðhöndla verki, mænuskaða eða maga- og garnasjúkdóma |
| NO20041964A NO20041964L (no) | 2001-10-03 | 2004-04-27 | 4-[Piperidin-4-yliden-(3-karbamoylfenyl)metyl]benzamidderivater og deres anvendelse ved behandling av smerte, spinalskader og gastrointestinale forstyrrelser |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0103313A SE0103313D0 (sv) | 2001-10-03 | 2001-10-03 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0103313D0 true SE0103313D0 (sv) | 2001-10-03 |
Family
ID=20285553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0103313A SE0103313D0 (sv) | 2001-10-03 | 2001-10-03 | Novel compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7205317B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1440060A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2005505583A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20040039469A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1692100A (cg-RX-API-DMAC7.html) |
| AR (1) | AR036649A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0212959A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2460168A1 (cg-RX-API-DMAC7.html) |
| CO (1) | CO5580822A2 (cg-RX-API-DMAC7.html) |
| HU (1) | HUP0401915A2 (cg-RX-API-DMAC7.html) |
| IL (1) | IL160889A0 (cg-RX-API-DMAC7.html) |
| IS (1) | IS7203A (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04003056A (cg-RX-API-DMAC7.html) |
| NO (1) | NO20041964L (cg-RX-API-DMAC7.html) |
| PL (1) | PL368804A1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2004107854A (cg-RX-API-DMAC7.html) |
| SE (1) | SE0103313D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003029215A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200402514B (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1269805C (zh) | 2001-05-18 | 2006-08-16 | 阿斯特拉曾尼卡有限公司 | 4－(苯基－哌嗪基－甲基)－苯甲酰胺衍生物及其在治疗疼痛、焦虑症或胃肠病中的应用 |
| SE0203302D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| CA2504723C (en) | 2002-11-07 | 2012-10-16 | Abbott Laboratories | Prosthesis with multiple drugs in discrete unmixed droplets |
| SE0203300D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0301445D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301442D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations therof and uses thereof |
| MXPA05012117A (es) * | 2003-05-16 | 2006-02-08 | Astrazeneca Ab | Derivados de diarilmetiliden piperidina, preparaciones de los mismos y usos de los mismos. |
| WO2005003131A1 (en) * | 2003-06-27 | 2005-01-13 | Janssen Pharmaceutica N.V. | Tricyclic delta opioid modulators |
| NZ593444A (en) | 2003-10-01 | 2012-12-21 | Adolor Corp | 4-[(2-N,N-diethylaminocarbonyl)pyrid-5-yl]-spiro[1,2-dihydronaphthalene-2,4'-piperidine] and methods of its use |
| US20100030183A1 (en) | 2004-03-19 | 2010-02-04 | Toner John L | Method of treating vascular disease at a bifurcated vessel using a coated balloon |
| ATE534424T1 (de) | 2004-03-19 | 2011-12-15 | Abbott Lab | Mehrfache arzneiabgabe aus einem ballon und eine prothese |
| MX2007001240A (es) | 2004-08-02 | 2007-03-23 | Astrazeneca Ab | Derivados de diarilmetil-piperazina, preparaciones y usos de las mismas. |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| CA2662115A1 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Methods for enhancing cognitive function |
| DK3233825T3 (da) | 2014-12-19 | 2020-06-29 | Pharmnovo Ab | Diarylmethylidenpiperidinderivater og deres anvendelse som deltaopioidreceptoragonister |
| WO2016099394A1 (en) * | 2014-12-19 | 2016-06-23 | Pharmnovo Ab | Novel selective delta-opioid receptor agonists useful for the treatment of pain, anxiety and depression. |
| CN116171277A (zh) * | 2020-07-17 | 2023-05-26 | 菲勒诺沃公司 | Pn6047盐酸盐的多晶型物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) * | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) * | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) * | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) * | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) * | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| US5574159A (en) * | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| ZA9811842B (en) | 1997-12-24 | 2000-06-23 | Ortho Mcneil Pharm Inc | 4-[aryl(piperidin-4-yl)]aminobenzamides. |
| SE0001208D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0001207D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-10-03 SE SE0103313A patent/SE0103313D0/xx unknown
-
2002
- 2002-09-27 AR ARP020103670A patent/AR036649A1/es unknown
- 2002-10-02 CA CA002460168A patent/CA2460168A1/en not_active Abandoned
- 2002-10-02 KR KR10-2004-7004780A patent/KR20040039469A/ko not_active Withdrawn
- 2002-10-02 MX MXPA04003056A patent/MXPA04003056A/es unknown
- 2002-10-02 JP JP2003532465A patent/JP2005505583A/ja not_active Abandoned
- 2002-10-02 RU RU2004107854/04A patent/RU2004107854A/ru not_active Application Discontinuation
- 2002-10-02 HU HU0401915A patent/HUP0401915A2/hu unknown
- 2002-10-02 PL PL02368804A patent/PL368804A1/xx not_active Application Discontinuation
- 2002-10-02 BR BR0212959-0A patent/BR0212959A/pt not_active Application Discontinuation
- 2002-10-02 WO PCT/SE2002/001804 patent/WO2003029215A1/en not_active Ceased
- 2002-10-02 US US10/491,263 patent/US7205317B2/en not_active Expired - Fee Related
- 2002-10-02 IL IL16088902A patent/IL160889A0/xx unknown
- 2002-10-02 CN CNA028195825A patent/CN1692100A/zh active Pending
- 2002-10-02 EP EP02775640A patent/EP1440060A1/en not_active Withdrawn
-
2004
- 2004-03-30 ZA ZA200402514A patent/ZA200402514B/xx unknown
- 2004-03-31 CO CO04030712A patent/CO5580822A2/es not_active Application Discontinuation
- 2004-03-31 IS IS7203A patent/IS7203A/is unknown
- 2004-04-27 NO NO20041964A patent/NO20041964L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR036649A1 (es) | 2004-09-22 |
| ZA200402514B (en) | 2005-01-24 |
| WO2003029215A1 (en) | 2003-04-10 |
| IS7203A (is) | 2004-03-31 |
| JP2005505583A (ja) | 2005-02-24 |
| NO20041964L (no) | 2004-04-27 |
| CN1692100A (zh) | 2005-11-02 |
| CA2460168A1 (en) | 2003-04-10 |
| RU2004107854A (ru) | 2005-09-10 |
| IL160889A0 (en) | 2004-08-31 |
| HUP0401915A2 (hu) | 2005-01-28 |
| EP1440060A1 (en) | 2004-07-28 |
| MXPA04003056A (es) | 2004-07-05 |
| PL368804A1 (en) | 2005-04-04 |
| BR0212959A (pt) | 2004-10-13 |
| KR20040039469A (ko) | 2004-05-10 |
| US7205317B2 (en) | 2007-04-17 |
| CO5580822A2 (es) | 2005-11-30 |
| US20050020629A1 (en) | 2005-01-27 |
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