IL160889A0 - 4 [piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders - Google Patents
4 [piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disordersInfo
- Publication number
- IL160889A0 IL160889A0 IL16088902A IL16088902A IL160889A0 IL 160889 A0 IL160889 A0 IL 160889A0 IL 16088902 A IL16088902 A IL 16088902A IL 16088902 A IL16088902 A IL 16088902A IL 160889 A0 IL160889 A0 IL 160889A0
- Authority
- IL
- Israel
- Prior art keywords
- yliden
- carbamoylphenyl
- piperidin
- pain
- methyl
- Prior art date
Links
- OQISSLABMNMNLZ-UHFFFAOYSA-N 3-[benzamido(piperidin-4-ylidene)methyl]benzamide Chemical class NC(=O)c1cccc(c1)C(NC(=O)c1ccccc1)=C1CCNCC1 OQISSLABMNMNLZ-UHFFFAOYSA-N 0.000 title 1
- 208000018522 Gastrointestinal disease Diseases 0.000 title 1
- 208000002193 Pain Diseases 0.000 title 1
- 208000020339 Spinal injury Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0103313A SE0103313D0 (sv) | 2001-10-03 | 2001-10-03 | Novel compounds |
| PCT/SE2002/001804 WO2003029215A1 (en) | 2001-10-03 | 2002-10-02 | 4[piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL160889A0 true IL160889A0 (en) | 2004-08-31 |
Family
ID=20285553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16088902A IL160889A0 (en) | 2001-10-03 | 2002-10-02 | 4 [piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7205317B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1440060A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2005505583A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20040039469A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1692100A (cg-RX-API-DMAC7.html) |
| AR (1) | AR036649A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0212959A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2460168A1 (cg-RX-API-DMAC7.html) |
| CO (1) | CO5580822A2 (cg-RX-API-DMAC7.html) |
| HU (1) | HUP0401915A2 (cg-RX-API-DMAC7.html) |
| IL (1) | IL160889A0 (cg-RX-API-DMAC7.html) |
| IS (1) | IS7203A (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04003056A (cg-RX-API-DMAC7.html) |
| NO (1) | NO20041964L (cg-RX-API-DMAC7.html) |
| PL (1) | PL368804A1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2004107854A (cg-RX-API-DMAC7.html) |
| SE (1) | SE0103313D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003029215A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200402514B (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1269805C (zh) | 2001-05-18 | 2006-08-16 | 阿斯特拉曾尼卡有限公司 | 4－(苯基－哌嗪基－甲基)－苯甲酰胺衍生物及其在治疗疼痛、焦虑症或胃肠病中的应用 |
| SE0203302D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| CA2504723C (en) | 2002-11-07 | 2012-10-16 | Abbott Laboratories | Prosthesis with multiple drugs in discrete unmixed droplets |
| SE0203300D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0301445D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301442D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations therof and uses thereof |
| MXPA05012117A (es) * | 2003-05-16 | 2006-02-08 | Astrazeneca Ab | Derivados de diarilmetiliden piperidina, preparaciones de los mismos y usos de los mismos. |
| WO2005003131A1 (en) * | 2003-06-27 | 2005-01-13 | Janssen Pharmaceutica N.V. | Tricyclic delta opioid modulators |
| NZ593444A (en) | 2003-10-01 | 2012-12-21 | Adolor Corp | 4-[(2-N,N-diethylaminocarbonyl)pyrid-5-yl]-spiro[1,2-dihydronaphthalene-2,4'-piperidine] and methods of its use |
| US20100030183A1 (en) | 2004-03-19 | 2010-02-04 | Toner John L | Method of treating vascular disease at a bifurcated vessel using a coated balloon |
| ATE534424T1 (de) | 2004-03-19 | 2011-12-15 | Abbott Lab | Mehrfache arzneiabgabe aus einem ballon und eine prothese |
| MX2007001240A (es) | 2004-08-02 | 2007-03-23 | Astrazeneca Ab | Derivados de diarilmetil-piperazina, preparaciones y usos de las mismas. |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| CA2662115A1 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Methods for enhancing cognitive function |
| DK3233825T3 (da) | 2014-12-19 | 2020-06-29 | Pharmnovo Ab | Diarylmethylidenpiperidinderivater og deres anvendelse som deltaopioidreceptoragonister |
| WO2016099394A1 (en) * | 2014-12-19 | 2016-06-23 | Pharmnovo Ab | Novel selective delta-opioid receptor agonists useful for the treatment of pain, anxiety and depression. |
| CN116171277A (zh) * | 2020-07-17 | 2023-05-26 | 菲勒诺沃公司 | Pn6047盐酸盐的多晶型物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) * | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) * | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) * | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) * | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) * | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| US5574159A (en) * | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| ZA9811842B (en) | 1997-12-24 | 2000-06-23 | Ortho Mcneil Pharm Inc | 4-[aryl(piperidin-4-yl)]aminobenzamides. |
| SE0001208D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0001207D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-10-03 SE SE0103313A patent/SE0103313D0/xx unknown
-
2002
- 2002-09-27 AR ARP020103670A patent/AR036649A1/es unknown
- 2002-10-02 CA CA002460168A patent/CA2460168A1/en not_active Abandoned
- 2002-10-02 KR KR10-2004-7004780A patent/KR20040039469A/ko not_active Withdrawn
- 2002-10-02 MX MXPA04003056A patent/MXPA04003056A/es unknown
- 2002-10-02 JP JP2003532465A patent/JP2005505583A/ja not_active Abandoned
- 2002-10-02 RU RU2004107854/04A patent/RU2004107854A/ru not_active Application Discontinuation
- 2002-10-02 HU HU0401915A patent/HUP0401915A2/hu unknown
- 2002-10-02 PL PL02368804A patent/PL368804A1/xx not_active Application Discontinuation
- 2002-10-02 BR BR0212959-0A patent/BR0212959A/pt not_active Application Discontinuation
- 2002-10-02 WO PCT/SE2002/001804 patent/WO2003029215A1/en not_active Ceased
- 2002-10-02 US US10/491,263 patent/US7205317B2/en not_active Expired - Fee Related
- 2002-10-02 IL IL16088902A patent/IL160889A0/xx unknown
- 2002-10-02 CN CNA028195825A patent/CN1692100A/zh active Pending
- 2002-10-02 EP EP02775640A patent/EP1440060A1/en not_active Withdrawn
-
2004
- 2004-03-30 ZA ZA200402514A patent/ZA200402514B/xx unknown
- 2004-03-31 CO CO04030712A patent/CO5580822A2/es not_active Application Discontinuation
- 2004-03-31 IS IS7203A patent/IS7203A/is unknown
- 2004-04-27 NO NO20041964A patent/NO20041964L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR036649A1 (es) | 2004-09-22 |
| ZA200402514B (en) | 2005-01-24 |
| WO2003029215A1 (en) | 2003-04-10 |
| IS7203A (is) | 2004-03-31 |
| JP2005505583A (ja) | 2005-02-24 |
| NO20041964L (no) | 2004-04-27 |
| CN1692100A (zh) | 2005-11-02 |
| CA2460168A1 (en) | 2003-04-10 |
| RU2004107854A (ru) | 2005-09-10 |
| SE0103313D0 (sv) | 2001-10-03 |
| HUP0401915A2 (hu) | 2005-01-28 |
| EP1440060A1 (en) | 2004-07-28 |
| MXPA04003056A (es) | 2004-07-05 |
| PL368804A1 (en) | 2005-04-04 |
| BR0212959A (pt) | 2004-10-13 |
| KR20040039469A (ko) | 2004-05-10 |
| US7205317B2 (en) | 2007-04-17 |
| CO5580822A2 (es) | 2005-11-30 |
| US20050020629A1 (en) | 2005-01-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL367142A1 (en) | 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| IL160889A0 (en) | 4 [piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders | |
| PL376894A1 (pl) | Pochodne 4-(fenylopiperazynylometylo) benzamidu i ich zastosowanie do leczenia bólu lub zaburzeń żołądkowo-jelitowych | |
| IL158704A0 (en) | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| PL376895A1 (pl) | Pochodne 4-(fenylopiperazynylometylo) benzamidu i ich zastosowanie do leczenia bólu lub zaburzeń żołądkowo-jelitowych | |
| IL158703A0 (en) | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| AU2003278664A1 (en) | 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders | |
| IL160018A0 (en) | Isoxazolopyridinones and use thereof in the treatment of parkinson's disease | |
| GB0128674D0 (en) | Treatment of sleep disorders and the like | |
| IL158632A0 (en) | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| IL158695A0 (en) | 4-(phenyl-piperidin-4-yldine-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| IL158628A0 (en) | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| IL158630A0 (en) | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| IL158629A0 (en) | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| HK1066217A (en) | 4[piperidin-4-yliden-(3-carbamoylphenyl)methyl] benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders | |
| IL158700A0 (en) | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| EP1440163A4 (en) | METHOD AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF PAIN DISEASES USING 46566 | |
| HK1079515A (en) | 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders | |
| HK1079516A (en) | 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders | |
| EP1440169A4 (en) | METHOD AND COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF PAIN-SPECIFIC DISORDERS USING 57749 | |
| HK1061032A (en) | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| HK1061027A (en) | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| HK1061248A (en) | 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | |
| HK1061028A (en) | 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders | |
| HUP0202416A3 (en) | Novel pharmaceutical combination and it's use for the treatment of certain cardiovascular disorders |