RU99117701A - AMORPHOUS, CARBONATED AND FLUORINATED HYDROXYAPATITIS FOR DENTAL PASTES AND METHOD FOR ITS PREPARATION - Google Patents

AMORPHOUS, CARBONATED AND FLUORINATED HYDROXYAPATITIS FOR DENTAL PASTES AND METHOD FOR ITS PREPARATION

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Publication number
RU99117701A
RU99117701A RU99117701/14A RU99117701A RU99117701A RU 99117701 A RU99117701 A RU 99117701A RU 99117701/14 A RU99117701/14 A RU 99117701/14A RU 99117701 A RU99117701 A RU 99117701A RU 99117701 A RU99117701 A RU 99117701A
Authority
RU
Russia
Prior art keywords
amorphous
carbonated
fluorinated
calcium
hydroxyapatite
Prior art date
Application number
RU99117701/14A
Other languages
Russian (ru)
Other versions
RU2179437C2 (en
Inventor
Павел Александрович Арсеньев
Виктор Николаевич Балин
Юрий Федорович Дощицын
Анатолий Аркадьевич Евдокимов
Александр Владимирович Пташко
Анатолий Федорович Феоктистов
Original Assignee
Ооо Нпф "Медкам"
Filing date
Publication date
Application filed by Ооо Нпф "Медкам" filed Critical Ооо Нпф "Медкам"
Priority to RU99117701A priority Critical patent/RU2179437C2/en
Priority claimed from RU99117701A external-priority patent/RU2179437C2/en
Publication of RU99117701A publication Critical patent/RU99117701A/en
Application granted granted Critical
Publication of RU2179437C2 publication Critical patent/RU2179437C2/en

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Claims (2)

1. Аморфный, карбонированный и фторированный гидроксиапатит для зубных паст и способ его получения:
1. Включающий синтезированный, неорганический материал состава Са10(РО4)6(ОН)2 со структурой гидроскиапатита, отличающийся тем, что он дополнительно содержит изоморфно введенные карбонатные группы и фтор-группы, при этом в аморфном гидроксиапатите замещение (ОН)-1 групп ионами (СО3)-2 и F-1 проводится одновременно и в соответствие с формулой Ca10(PО4)6(OH)2-x-y(COx/2)Fy, где х = 0,01 - 0,3, у = 0,01 - 0,4.1. Amorphous, carbonated and fluorinated hydroxyapatite for toothpastes and method for its production:
1. Including synthesized, inorganic material of composition Ca 10 (PO 4 ) 6 (OH) 2 with the structure of hydrocyapiapite, characterized in that it additionally contains isomorphically introduced carbonate groups and fluorine groups, while in the amorphous hydroxyapatite substitution (OH) -1 groups of ions (CO 3 ) -2 and F -1 is carried out simultaneously and in accordance with the formula Ca 10 (PO 4 ) 6 (OH) 2-xy (CO x / 2 ) F y , where x = 0.01 - 0, 3, y = 0.01 - 0.4. 2. Включающий смещение водной суспензии гидроксида кальция с водным раствором фосфорной кислоты, отделение реакционного осадка и концентрирование его, отличающийся тем, что синтез проводится при 8-10oС в процессе медленного осаждения одновременно аморфного, карбонированного и фторированного гидроксиапатита из раствора гидроксида кальция смесью ортофосфорной и фтористоводородной кислот при одновременном и равномерном добавлении в реакционный раствор бикарбоната кальция (в инертной атмосфере), причем количества фтористоводородной кислоты и бикарбоната кальция определяются конкретной формулой осаждаемого соединения, процесс осаждения прекращается при достижении рН 7,2-7,5 в реакционном растворе, а образцы для контроля качества продукта готовятся путем сушки взятых проб при температуре (100-200oС) с последующим отжигом при температуре (600-800oС) в течение 2-6 ч.2. Including the displacement of an aqueous suspension of calcium hydroxide with an aqueous solution of phosphoric acid, separating the reaction precipitate and concentrating it, characterized in that the synthesis is carried out at 8-10 o С in the process of slow precipitation of simultaneously amorphous, carbonated and fluorinated hydroxyapatite from a solution of calcium hydroxide with a mixture of phosphoric acid and hydrofluoric acid while simultaneously adding calcium bicarbonate (in an inert atmosphere) to the reaction solution, and the amount of hydrofluoric acid Calcium slots and calcium bicarbonate are determined by the specific formula of the precipitated compound, the precipitation process is stopped when the pH reaches 7.2-7.5 in the reaction solution, and samples for quality control of the product are prepared by drying the samples taken at a temperature (100-200 o C) with subsequent annealing at a temperature (600-800 o С) for 2-6 hours.
RU99117701A 1999-08-19 1999-08-19 Amorphous carbonized and fluorinated hydroxyapatite for tooth paste and method for its obtaining RU2179437C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU99117701A RU2179437C2 (en) 1999-08-19 1999-08-19 Amorphous carbonized and fluorinated hydroxyapatite for tooth paste and method for its obtaining

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU99117701A RU2179437C2 (en) 1999-08-19 1999-08-19 Amorphous carbonized and fluorinated hydroxyapatite for tooth paste and method for its obtaining

Publications (2)

Publication Number Publication Date
RU99117701A true RU99117701A (en) 2001-06-10
RU2179437C2 RU2179437C2 (en) 2002-02-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU99117701A RU2179437C2 (en) 1999-08-19 1999-08-19 Amorphous carbonized and fluorinated hydroxyapatite for tooth paste and method for its obtaining

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2713992T3 (en) 2011-05-26 2017-12-18 Coswell Spa Dental care products comprising carbonate-substituted fluorohydroxyapatite particles
RU2465886C2 (en) * 2011-10-28 2012-11-10 Михаил Николаевич Михеев Product for manufacturing toothpastes and powders and method of its obtaining

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