RU97109845A - ANTI-HEMORROID COMPOSITIONS AND METHOD OF APPLICATION - Google Patents

ANTI-HEMORROID COMPOSITIONS AND METHOD OF APPLICATION

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Publication number
RU97109845A
RU97109845A RU97109845/14A RU97109845A RU97109845A RU 97109845 A RU97109845 A RU 97109845A RU 97109845/14 A RU97109845/14 A RU 97109845/14A RU 97109845 A RU97109845 A RU 97109845A RU 97109845 A RU97109845 A RU 97109845A
Authority
RU
Russia
Prior art keywords
composition
weight
amount
cellulose
water
Prior art date
Application number
RU97109845/14A
Other languages
Russian (ru)
Other versions
RU2159119C2 (en
Inventor
Бланко Ампаро
Original Assignee
Уайтхол Лаборэтриз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9422571A external-priority patent/GB9422571D0/en
Application filed by Уайтхол Лаборэтриз Лимитед filed Critical Уайтхол Лаборэтриз Лимитед
Publication of RU97109845A publication Critical patent/RU97109845A/en
Application granted granted Critical
Publication of RU2159119C2 publication Critical patent/RU2159119C2/en

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Claims (12)

1. Способ лечения геморроя у человека, страдающего им, который включает введение интраректально и/или в аноректальную область гелеобразной водной композиции, которая содержит одно или более лекарственных средств, эффективных при таком лечении и носитель, отличающийся тем, что композиция является водосодержащим гелем, включающим водорастворимое производное целлюлозы в качестве гелеобразующего вещества в количестве от примерно 0,2 до примерно 10 мас. % от массы композиции, пропиленгликоля в количестве от примерно 5 до примерно 45 мас. % от массы композиции и воды в количестве до примерно 94 мас.% от массы композиции.1. A method for the treatment of hemorrhoids in a person suffering from it, which includes the introduction of an intrarectal and / or anorectal region of a gel-like aqueous composition that contains one or more drugs effective in such treatment and a carrier, characterized in that the composition is a water-containing gel, including a water-soluble cellulose derivative as a gelling agent in an amount of from about 0.2 to about 10 wt. % by weight of the composition, propylene glycol in an amount of from about 5 to about 45 wt. % by weight of the composition and water in an amount up to about 94% by weight of the composition. 2. Способ лечения по п. 1, отличающийся тем, что лекарственным средством является вода гамамелиса. 2. The treatment method according to claim 1, characterized in that the drug is witch hazel water. 3. Способ лечения по п. 1, отличающийся тем, что производное целлюлозы является одним из следующих: гидроксиэтилцеллюлозой, гидроксипропилметилцеллюлозой, метилцеллюлозой, метилгидроксиэтилцеллюлозой, метилгидроксипропилцеллюлозой и карбоксиметилцеллюлозой или их комбинацией и присутствует в количестве от примерно 0,5 до примерно 5 мас.% от массы композиции. 3. The treatment method according to claim 1, wherein the cellulose derivative is one of the following: hydroxyethyl cellulose, hydroxypropyl methyl cellulose, methyl cellulose, methyl hydroxyethyl cellulose, methyl hydroxypropyl cellulose and carboxymethyl cellulose or a combination thereof and is present in an amount of from about 0.5 to about 5 wt. mass composition. 4. Гелеобразная водная композиция для интраректального введения при лечении геморроя и/или при лечении аноректального заболевания, которая содержит одно или более лекарственных средств, эффективных при таком лечении, и не являющихся кортикостероидами для местного применения, и носитель, отличающаяся тем, что она состоит из водорастворимого производного целлюлозы в качестве гелеобразующего вещества в количестве от примерно 0,2 до примерно 10 мас. % от массы композиции, пропиленгликоля в количестве от примерно 5 до примерно 45 мас.% от массы композиции и воды в количестве до 94 мас.% от массы композиции. 4. A gel-like aqueous composition for intrarectal administration in the treatment of hemorrhoids and / or in the treatment of anorectal disease, which contains one or more drugs effective for such treatment, and which are not corticosteroids for topical use, and a carrier, characterized in that it consists of water-soluble cellulose derivative as a gelling agent in an amount of from about 0.2 to about 10 wt. % by weight of the composition, propylene glycol in an amount of from about 5 to about 45% by weight of the composition and water in an amount of up to 94% by weight of the composition. 5. Композиция по п. 4, отличающаяся тем, что лекарственным средством является вода гамамелиса, и она присутствует в количестве от примерно 10 до примерно 60 мас.% от массы композиции. 5. The composition according to p. 4, characterized in that the drug is witch hazel water, and it is present in an amount of from about 10 to about 60 wt.% By weight of the composition. 6. Композиция по п. 4, отличающаяся тем, что она содержит фенилэфрина гидрохлорид в количестве до 0,35 мас.% от массы композиции. 6. The composition according to p. 4, characterized in that it contains phenylephrine hydrochloride in an amount up to 0.35 wt.% By weight of the composition. 7. Композиция по п. 4, отличающаяся тем, что производное целлюлозы является одним из следующих: гидроксиэтилцеллюлозой, гидроксипропилметилцеллюлозой, метилцеллюлозой, метилгидроксиэтилцеллюлозой, метилгидроксипропилцеллюлозой и карбоксиметилцеллюлозой или их комбинацией. 7. The composition according to p. 4, characterized in that the cellulose derivative is one of the following: hydroxyethyl cellulose, hydroxypropyl methyl cellulose, methyl cellulose, methyl hydroxyethyl cellulose, methyl hydroxypropyl cellulose and carboxymethyl cellulose, or a combination thereof. 8. Композиция по п. 4, отличающаяся тем, что производное целлюлозы присутствует в количестве от примерно 0,5 до примерно 5 мас.% от массы композиции. 8. The composition according to p. 4, characterized in that the cellulose derivative is present in an amount of from about 0.5 to about 5 wt.% By weight of the composition. 9. Композиция по п. 4, отличающаяся тем, что пропиленгликоль присутствует в количестве от примерно 10 до примерно 20 мас.% от массы композиции. 9. The composition according to p. 4, characterized in that the propylene glycol is present in an amount of from about 10 to about 20 wt.% By weight of the composition. 10. Композиция по п. 4, отличающаяся тем, что имеет вязкость от примерно 25000 спз до примерно 150000 спз @ 20oC.10. The composition according to p. 4, characterized in that it has a viscosity of from about 25,000 cps to about 150,000 cps @ 20 o C. 11. Композиция для лечения геморроя, состоящая в основном из примерно 50 мас. % воды гамамелиса, примерно от 10 до 20 мас.% пропиленгликоля, примерно от 1 до 2,5 мас.% гидроксиэтилцеллюлозы и воды qs до 100 процентов массы. 11. Composition for the treatment of hemorrhoids, consisting mainly of about 50 wt. % witch hazel water, about 10 to 20 wt.% propylene glycol, about 1 to 2.5 wt.% hydroxyethyl cellulose and water qs up to 100 percent by weight. 12. Композиция для лечения геморроя, состоящая по существу из воды гамамелиса в количестве примерно 50 мас.% от композиции; пропиленгликоля от примерно 10 до примерно 18 мас.% от массы композиции; гидроксиэтилцеллюлозы от примерно 1 до 3 мас.%, фенилэфрина гидрохлорида в количестве от примерно 0,2 до примерно 0,3 мас.% и дистиллированной воды qs до 100 процентов массы. 12. A composition for treating hemorrhoids, consisting essentially of witch hazel water in an amount of about 50% by weight of the composition; propylene glycol from about 10 to about 18 wt.% by weight of the composition; hydroxyethyl cellulose from about 1 to 3 wt.%, phenylephrine hydrochloride in an amount of from about 0.2 to about 0.3 wt.% and distilled water qs to 100 percent by weight.
RU97109845/14A 1994-11-09 1995-11-09 Composition and method of administration thereof RU2159119C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9422571A GB9422571D0 (en) 1994-11-09 1994-11-09 Haemorrihoidal compositions and method of use
GB9422571.1 1994-11-09

Publications (2)

Publication Number Publication Date
RU97109845A true RU97109845A (en) 1999-05-27
RU2159119C2 RU2159119C2 (en) 2000-11-20

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RU97109845/14A RU2159119C2 (en) 1994-11-09 1995-11-09 Composition and method of administration thereof

Country Status (31)

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US (3) US6565850B2 (en)
EP (1) EP0785770B1 (en)
JP (1) JP4555402B2 (en)
KR (1) KR100385247B1 (en)
CN (1) CN1101181C (en)
AR (1) AR002944A1 (en)
AT (1) ATE197122T1 (en)
AU (1) AU715566B2 (en)
BR (1) BR9509710A (en)
CA (1) CA2204769C (en)
CZ (1) CZ292100B6 (en)
DE (1) DE69519235T2 (en)
DK (1) DK0785770T3 (en)
ES (1) ES2151968T3 (en)
FI (1) FI119498B (en)
GB (1) GB9422571D0 (en)
GR (1) GR3034784T3 (en)
HK (1) HK1008187A1 (en)
HU (1) HU221480B (en)
IL (1) IL115891A (en)
MX (1) MX9703429A (en)
NO (1) NO319253B1 (en)
NZ (1) NZ295211A (en)
PL (1) PL182403B1 (en)
PT (1) PT785770E (en)
RO (1) RO116766B1 (en)
RU (1) RU2159119C2 (en)
SK (1) SK283421B6 (en)
TW (1) TW501932B (en)
WO (1) WO1996014828A1 (en)
ZA (1) ZA959438B (en)

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