RU94041225A - Антивирусные пептиды, способ получения, фармацевтическая композиция, способ лечения ретровирусных инфекций - Google Patents

Антивирусные пептиды, способ получения, фармацевтическая композиция, способ лечения ретровирусных инфекций

Info

Publication number
RU94041225A
RU94041225A RU94041225/04A RU94041225A RU94041225A RU 94041225 A RU94041225 A RU 94041225A RU 94041225/04 A RU94041225/04 A RU 94041225/04A RU 94041225 A RU94041225 A RU 94041225A RU 94041225 A RU94041225 A RU 94041225A
Authority
RU
Russia
Prior art keywords
alkyl
cycloalkyl
rmeans
heterocyclyl
aryl
Prior art date
Application number
RU94041225/04A
Other languages
English (en)
Inventor
Уилльям Грингрэсс Колин
Gb]
Дерек Альберт Стрит Стефен
Джон Уиттл Питер
Original Assignee
Пфайзер Инк. (US)
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929206462A external-priority patent/GB9206462D0/en
Priority claimed from GB939301638A external-priority patent/GB9301638D0/en
Application filed by Пфайзер Инк. (US), Пфайзер Инк. filed Critical Пфайзер Инк. (US)
Publication of RU94041225A publication Critical patent/RU94041225A/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Соединение общей формулы I, указанной в описании, и их фармацевтически приемлемые соли и биопредшественники являются ингибиторами ретровирусных протеаз, которые можно использовать для лечения или профилактики ретровирусных инфекций человека.

Claims (1)

  1. Соединение общей формулы I, указанной в описании, и их фармацевтически приемлемые соли и биопредшественники являются ингибиторами ретровирусных протеаз, которые можно использовать для лечения или профилактики ретровирусных инфекций человека.
RU94041225/04A 1992-03-25 1993-03-13 Антивирусные пептиды, способ получения, фармацевтическая композиция, способ лечения ретровирусных инфекций RU94041225A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929206462A GB9206462D0 (en) 1992-03-25 1992-03-25 Antiviral peptides
GB9206462.5 1992-03-25
GB9301638.4 1993-01-27
GB939301638A GB9301638D0 (en) 1993-01-27 1993-01-27 Antiviral peptides

Publications (1)

Publication Number Publication Date
RU94041225A true RU94041225A (ru) 1996-07-20

Family

ID=26300586

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94041225/04A RU94041225A (ru) 1992-03-25 1993-03-13 Антивирусные пептиды, способ получения, фармацевтическая композиция, способ лечения ретровирусных инфекций

Country Status (13)

Country Link
EP (1) EP0632808A1 (ru)
JP (1) JPH07501556A (ru)
KR (1) KR950700901A (ru)
AU (1) AU3748393A (ru)
BR (1) BR9306138A (ru)
CA (1) CA2131154A1 (ru)
CZ (1) CZ229594A3 (ru)
FI (1) FI944428A0 (ru)
HU (1) HU9402744D0 (ru)
NO (1) NO943540L (ru)
RU (1) RU94041225A (ru)
SK (1) SK114094A3 (ru)
WO (1) WO1993019059A1 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE143025T1 (de) * 1991-01-02 1996-10-15 Merrell Pharma Inc Antivirale verbindungen
WO1995001958A1 (en) * 1993-07-08 1995-01-19 Merrell Pharmaceuticals Inc. Difluoro statone analogs
NZ271825A (en) * 1993-09-09 1997-11-24 Merrell Pharma Inc Difluoro statone derivatives, preparation and pharmaceutical compositions thereof
US6114380A (en) * 1995-12-18 2000-09-05 Merrell Pharmaceuticals Inc. Difluoro statone analogs
GB9601680D0 (en) 1996-01-27 1996-03-27 Pfizer Ltd Therapeutic agents
ES2185307T3 (es) * 1998-02-02 2003-04-16 Lg Chemical Ltd Inhibidores de la farnesil transferasa que tienen una estructura piperidinica y procedimiento para su preparacion.
US6809200B2 (en) 2000-07-28 2004-10-26 Pfizer Inc. Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one compounds and intermediates thereof
BRPI0608178A2 (pt) 2005-04-14 2009-11-17 Hoffmann La Roche derivados de aminopirazol, sua fabricação, composição farmacêutica e uso como agentes farmacêuticos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91780A (en) * 1988-10-04 1995-08-31 Abbott Lab History of the amine of the xenon-preventing xanine acid, the process for their preparation and the pharmaceutical preparations containing them
IL92011A0 (en) * 1988-10-19 1990-07-12 Abbott Lab Heterocyclic peptide renin inhibitors
CA2010531A1 (en) * 1989-03-06 1990-09-06 Werner Neidhart Amino acid derivatives
EP0468998A1 (en) * 1989-04-18 1992-02-05 The Upjohn Company Peptides having novel polar n-terminal groups
DE4001236A1 (de) * 1990-01-18 1991-07-25 Bayer Ag Neue peptide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel, insbesondere als arzneimittel gegen retroviren

Also Published As

Publication number Publication date
CA2131154A1 (en) 1993-09-30
SK114094A3 (en) 1995-04-12
WO1993019059A1 (en) 1993-09-30
NO943540D0 (no) 1994-09-23
AU3748393A (en) 1993-10-21
CZ229594A3 (en) 1995-04-12
EP0632808A1 (en) 1995-01-11
FI944428A (fi) 1994-09-23
KR950700901A (ko) 1995-02-20
BR9306138A (pt) 1998-06-23
JPH07501556A (ja) 1995-02-16
HU9402744D0 (en) 1994-12-28
FI944428A0 (fi) 1994-09-23
NO943540L (no) 1994-11-21

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