RU93046415A - ALKYLENEDIAMINE DERIVATIVES - Google Patents
ALKYLENEDIAMINE DERIVATIVESInfo
- Publication number
- RU93046415A RU93046415A RU93046415/04A RU93046415A RU93046415A RU 93046415 A RU93046415 A RU 93046415A RU 93046415/04 A RU93046415/04 A RU 93046415/04A RU 93046415 A RU93046415 A RU 93046415A RU 93046415 A RU93046415 A RU 93046415A
- Authority
- RU
- Russia
- Prior art keywords
- substituted
- alkylenediamine derivatives
- naphthyl
- sulfur
- integer
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000001624 naphthyl group Chemical group 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N oxygen Chemical group O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 239000011593 sulfur Chemical group 0.000 claims 2
- 206010013990 Dysuria Diseases 0.000 claims 1
- 125000005263 alkylenediamine group Chemical group 0.000 claims 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 125000001841 imino group Chemical group [H]N=* 0.000 claims 1
Claims (1)
где R1 представляет собой водород, алкильную группу, либо замещенную или незамещенную фенильную, нафтильную или ароматическую гетероциклическую группу, R2 - замещенную или незамещенную фенильную, нафтильную или ароматическую гетероциклическую группу, R3 и R4 - водород, алкил, аралкил, или арил, либо R3 и R4, взятые вместе, образуют одну из замещенных или незамещенных гетероциклических групп с 5 - 7 членами, X - кислород, серу или имино, Y - кислород или серу, Z - -CH2-, -CO- или -CS-, m является целым числом от 0 до 4, n является целым числом от 0 до 4, r равно 0 или 1, а p и q являются целыми числами от 0 до 5, при условии, что p + q = 1 - 5.The invention relates to new alkylenediamine derivatives, which have the following formula and are effective for the treatment of dysuria:
where R 1 is hydrogen, an alkyl group, or a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group, R 2 is a substituted or unsubstituted phenyl, naphthyl or aromatic heterocyclic group, R 3 and R 4 are hydrogen, alkyl, aralkyl, or aryl , or R 3 and R 4 , taken together, form one of the substituted or unsubstituted heterocyclic groups with 5-7 members, X is oxygen, sulfur or imino, Y is oxygen or sulfur, Z is -CH 2 -, -CO- or -CS-, m is an integer from 0 to 4, n is an integer from 0 to 4, r is 0 or 1, and p and q are integers from 0 to 5, provided that p + q = 1 - 5.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20971392 | 1992-07-14 | ||
| JP4-209713 | 1992-07-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93046415A true RU93046415A (en) | 1995-12-27 |
| RU2069661C1 RU2069661C1 (en) | 1996-11-27 |
Family
ID=16577418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93046415/04A RU2069661C1 (en) | 1992-07-14 | 1993-07-14 | Alkylenediamine derivatives or their pharmaceutically acceptable salts |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0579169B1 (en) |
| JP (1) | JP2866277B2 (en) |
| KR (1) | KR100293334B1 (en) |
| CN (1) | CN1045597C (en) |
| AT (1) | ATE170516T1 (en) |
| AU (1) | AU659561B2 (en) |
| CA (1) | CA2100376A1 (en) |
| DE (1) | DE69320730T2 (en) |
| DK (1) | DK0579169T3 (en) |
| ES (1) | ES2121036T3 (en) |
| FI (1) | FI933206A (en) |
| HU (1) | HU221196B1 (en) |
| MX (1) | MX9304259A (en) |
| NO (1) | NO303827B1 (en) |
| PH (1) | PH31474A (en) |
| RU (1) | RU2069661C1 (en) |
| TW (1) | TW300895B (en) |
| ZA (1) | ZA935074B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2084995A (en) * | 1994-03-31 | 1995-10-23 | Nippon Chemiphar Co. Ltd. | Alkylenediamine derivative |
| US5563277A (en) * | 1994-12-21 | 1996-10-08 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
| TW200732313A (en) * | 2005-12-15 | 2007-09-01 | Astrazeneca Ab | Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators |
| EP3229807A4 (en) | 2014-12-11 | 2018-10-17 | President and Fellows of Harvard College | Inhibitors of cellular necrosis and related methods |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3576808A (en) * | 1967-09-15 | 1971-04-27 | Miles Lab | N-4-phenyl-1-piperazinylalkyl-5-phenyl-oxazolidinones |
| JPS6183170A (en) * | 1984-09-28 | 1986-04-26 | Nippon Chemiphar Co Ltd | Novel 1,3-oxazolidin-2-one derivative and its preparation |
-
1993
- 1993-07-13 AT AT93111194T patent/ATE170516T1/en not_active IP Right Cessation
- 1993-07-13 TW TW082105576A patent/TW300895B/zh active
- 1993-07-13 PH PH46513A patent/PH31474A/en unknown
- 1993-07-13 DE DE69320730T patent/DE69320730T2/en not_active Expired - Fee Related
- 1993-07-13 DK DK93111194T patent/DK0579169T3/en active
- 1993-07-13 CA CA002100376A patent/CA2100376A1/en not_active Abandoned
- 1993-07-13 ES ES93111194T patent/ES2121036T3/en not_active Expired - Lifetime
- 1993-07-13 EP EP93111194A patent/EP0579169B1/en not_active Expired - Lifetime
- 1993-07-14 MX MX9304259A patent/MX9304259A/en not_active IP Right Cessation
- 1993-07-14 FI FI933206A patent/FI933206A/en unknown
- 1993-07-14 KR KR1019930013242A patent/KR100293334B1/en not_active IP Right Cessation
- 1993-07-14 RU RU93046415/04A patent/RU2069661C1/en not_active IP Right Cessation
- 1993-07-14 HU HU9302017A patent/HU221196B1/en not_active IP Right Cessation
- 1993-07-14 JP JP5196797A patent/JP2866277B2/en not_active Expired - Fee Related
- 1993-07-14 ZA ZA935074A patent/ZA935074B/en unknown
- 1993-07-14 NO NO932551A patent/NO303827B1/en unknown
- 1993-07-14 CN CN93116490A patent/CN1045597C/en not_active Expired - Fee Related
- 1993-07-14 AU AU41958/93A patent/AU659561B2/en not_active Ceased
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