RU93043627A -
PHARMACEUTICAL COMPOSITION, CONTAINING A COMPLEX OF RESIN AND POLYAMINIC DRUGS
- Google Patents
PHARMACEUTICAL COMPOSITION, CONTAINING A COMPLEX OF RESIN AND POLYAMINIC DRUGS
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Publication number
RU93043627A
RU93043627ARU93043627/14ARU93043627ARU93043627ARU 93043627 ARU93043627 ARU 93043627ARU 93043627/14 ARU93043627/14 ARU 93043627/14ARU 93043627 ARU93043627 ARU 93043627ARU 93043627 ARU93043627 ARU 93043627A
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Application filed by Ричардсон-Викс Инк.filedCriticalРичардсон-Викс Инк.
Publication of RU93043627ApublicationCriticalpatent/RU93043627A/en
Предлагаемые фармацевтические композиции состоят из фармакологически активных полиаминовых препаратов, связанных с катионообменной смолой с образованием комплекса препарат-смола, в котором содержание лекарственного препарата выше, чем один эквивалент амина на эквивалент актионообменника. Этот комплекс препарат-смола необязательно покрыт водопроницаемым диффузионным барьерным покрытием, которое нерастворимо в желудочно-кишечных жидкостях и обеспечивает контролируемое высвобождение препарата в желудочно-кишечном тракте.The proposed pharmaceutical compositions consist of pharmacologically active polyamine preparations associated with a cation-exchange resin with the formation of a drug-resin complex, in which the content of the drug is higher than one equivalent of amine per equivalent of an actio-exchanger. This drug-resin complex is optionally coated with a permeable diffusion barrier coating that is insoluble in the gastrointestinal fluids and provides controlled release of the drug in the gastrointestinal tract.
RU93043627/14A1990-12-211991-12-16
PHARMACEUTICAL COMPOSITION, CONTAINING A COMPLEX OF RESIN AND POLYAMINIC DRUGS
RU93043627A
(en)
Process for the preparation of an osmotic delivering oral delivery system containing a moderately water-soluble, pharmaceutically acceptable salt of metoprolol