ES2120354A1 - Therapeutic device for targeting drugs at the desired section of the gastrointestinal tract, depending on the physicochemical characteristics thereof. - Google Patents

Therapeutic device for targeting drugs at the desired section of the gastrointestinal tract, depending on the physicochemical characteristics thereof.

Info

Publication number
ES2120354A1
ES2120354A1 ES09600385A ES9600385A ES2120354A1 ES 2120354 A1 ES2120354 A1 ES 2120354A1 ES 09600385 A ES09600385 A ES 09600385A ES 9600385 A ES9600385 A ES 9600385A ES 2120354 A1 ES2120354 A1 ES 2120354A1
Authority
ES
Spain
Prior art keywords
depending
gastrointestinal tract
drug
physicochemical characteristics
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09600385A
Other languages
Spanish (es)
Other versions
ES2120354B1 (en
Inventor
Alvarez Antonio Maria Rabasco
Rodriguez Maria Luisa Gonzalez
Hervas Maria Jose Fernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Sevilla
Original Assignee
Universidad de Sevilla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Sevilla filed Critical Universidad de Sevilla
Priority to ES9600385A priority Critical patent/ES2120354B1/en
Publication of ES2120354A1 publication Critical patent/ES2120354A1/en
Application granted granted Critical
Publication of ES2120354B1 publication Critical patent/ES2120354B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

Therapeutic device for targeting drugs at the desired section of the gastrointestinal tract, depending on the physicochemical characteristics thereof. The present invention relates to a device of the inert polymer matrix type for controlled release of drugs, principally of a peptide nature, consisting in a matrix tablet made with an insoluble resin, for example Eudragit R RS 100, a channelling substance, for example Emdex R type modified dextrose, sodium chloride or mannitol, and which contains the drug carried in a granule type galenic form placed in the centre of the matrix tablet. This device can be used in the pharmaceutical industry for optimizing drug therapies administered by the oral route, since, depending on a number of variables present in the formulation, the device allows the release of the active principle to be modified in accordance with the basic objectives of a controlled release system, ensuring the release of the drug in a particular section of the gastrointestinal tract and achieving a constant rate of penetration into plasma.
ES9600385A 1996-02-12 1996-02-12 THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME. Expired - Fee Related ES2120354B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9600385A ES2120354B1 (en) 1996-02-12 1996-02-12 THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9600385A ES2120354B1 (en) 1996-02-12 1996-02-12 THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME.

Publications (2)

Publication Number Publication Date
ES2120354A1 true ES2120354A1 (en) 1998-10-16
ES2120354B1 ES2120354B1 (en) 1999-07-01

Family

ID=8293853

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9600385A Expired - Fee Related ES2120354B1 (en) 1996-02-12 1996-02-12 THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME.

Country Status (1)

Country Link
ES (1) ES2120354B1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0297650A1 (en) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions with controlled zero-order delivery rate and method of preparing these compositions
ES2059729T3 (en) * 1988-03-31 1994-11-16 Tanabe Seiyaku Co PHARMACEUTICAL PREPARATION FOR CONTROLLED LIBERATION AND METHOD TO PRODUCE THE SAME.
ES2067957T3 (en) * 1990-08-07 1995-04-01 Pfizer USE OF INTERFACE POLYMERIZED MEMBRANES IN RELEASE DEVICES.
EP0671168A1 (en) * 1994-03-11 1995-09-13 Tanabe Seiyaku Co., Ltd. Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0297650A1 (en) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions with controlled zero-order delivery rate and method of preparing these compositions
ES2059729T3 (en) * 1988-03-31 1994-11-16 Tanabe Seiyaku Co PHARMACEUTICAL PREPARATION FOR CONTROLLED LIBERATION AND METHOD TO PRODUCE THE SAME.
ES2067957T3 (en) * 1990-08-07 1995-04-01 Pfizer USE OF INTERFACE POLYMERIZED MEMBRANES IN RELEASE DEVICES.
EP0671168A1 (en) * 1994-03-11 1995-09-13 Tanabe Seiyaku Co., Ltd. Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract

Also Published As

Publication number Publication date
ES2120354B1 (en) 1999-07-01

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