ES2120354A1 - Therapeutic device for targeting drugs at the desired section of the gastrointestinal tract, depending on the physicochemical characteristics thereof. - Google Patents
Therapeutic device for targeting drugs at the desired section of the gastrointestinal tract, depending on the physicochemical characteristics thereof.Info
- Publication number
- ES2120354A1 ES2120354A1 ES09600385A ES9600385A ES2120354A1 ES 2120354 A1 ES2120354 A1 ES 2120354A1 ES 09600385 A ES09600385 A ES 09600385A ES 9600385 A ES9600385 A ES 9600385A ES 2120354 A1 ES2120354 A1 ES 2120354A1
- Authority
- ES
- Spain
- Prior art keywords
- depending
- gastrointestinal tract
- drug
- physicochemical characteristics
- release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Therapeutic device for targeting drugs at the desired section of the gastrointestinal tract, depending on the physicochemical characteristics thereof. The present invention relates to a device of the inert polymer matrix type for controlled release of drugs, principally of a peptide nature, consisting in a matrix tablet made with an insoluble resin, for example Eudragit R RS 100, a channelling substance, for example Emdex R type modified dextrose, sodium chloride or mannitol, and which contains the drug carried in a granule type galenic form placed in the centre of the matrix tablet. This device can be used in the pharmaceutical industry for optimizing drug therapies administered by the oral route, since, depending on a number of variables present in the formulation, the device allows the release of the active principle to be modified in accordance with the basic objectives of a controlled release system, ensuring the release of the drug in a particular section of the gastrointestinal tract and achieving a constant rate of penetration into plasma.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9600385A ES2120354B1 (en) | 1996-02-12 | 1996-02-12 | THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9600385A ES2120354B1 (en) | 1996-02-12 | 1996-02-12 | THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2120354A1 true ES2120354A1 (en) | 1998-10-16 |
ES2120354B1 ES2120354B1 (en) | 1999-07-01 |
Family
ID=8293853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9600385A Expired - Fee Related ES2120354B1 (en) | 1996-02-12 | 1996-02-12 | THERAPEUTIC DEVICE TO DIRECT PHARMACES TOWARDS THE DESIRED GASTROINTESTINAL TRACT SECTION DEPENDING ON THE PHYSICOCHEMICAL CHARACTERISTICS OF THE SAME. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2120354B1 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0297650A1 (en) * | 1987-06-26 | 1989-01-04 | Duphar International Research B.V | Compositions with controlled zero-order delivery rate and method of preparing these compositions |
ES2059729T3 (en) * | 1988-03-31 | 1994-11-16 | Tanabe Seiyaku Co | PHARMACEUTICAL PREPARATION FOR CONTROLLED LIBERATION AND METHOD TO PRODUCE THE SAME. |
ES2067957T3 (en) * | 1990-08-07 | 1995-04-01 | Pfizer | USE OF INTERFACE POLYMERIZED MEMBRANES IN RELEASE DEVICES. |
EP0671168A1 (en) * | 1994-03-11 | 1995-09-13 | Tanabe Seiyaku Co., Ltd. | Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract |
-
1996
- 1996-02-12 ES ES9600385A patent/ES2120354B1/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0297650A1 (en) * | 1987-06-26 | 1989-01-04 | Duphar International Research B.V | Compositions with controlled zero-order delivery rate and method of preparing these compositions |
ES2059729T3 (en) * | 1988-03-31 | 1994-11-16 | Tanabe Seiyaku Co | PHARMACEUTICAL PREPARATION FOR CONTROLLED LIBERATION AND METHOD TO PRODUCE THE SAME. |
ES2067957T3 (en) * | 1990-08-07 | 1995-04-01 | Pfizer | USE OF INTERFACE POLYMERIZED MEMBRANES IN RELEASE DEVICES. |
EP0671168A1 (en) * | 1994-03-11 | 1995-09-13 | Tanabe Seiyaku Co., Ltd. | Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract |
Also Published As
Publication number | Publication date |
---|---|
ES2120354B1 (en) | 1999-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19981016 Kind code of ref document: A1 Effective date: 19981016 |
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FD2A | Announcement of lapse in spain |
Effective date: 20160526 |