RU93042470A - METHOD FOR PRODUCING POLYOXICYCLOPENTANE DERIVATIVES, STRAINS - Google Patents

METHOD FOR PRODUCING POLYOXICYCLOPENTANE DERIVATIVES, STRAINS

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Publication number
RU93042470A
RU93042470A RU93042470/13A RU93042470A RU93042470A RU 93042470 A RU93042470 A RU 93042470A RU 93042470/13 A RU93042470/13 A RU 93042470/13A RU 93042470 A RU93042470 A RU 93042470A RU 93042470 A RU93042470 A RU 93042470A
Authority
RU
Russia
Prior art keywords
polyoxicyclopentane
strains
derivatives
producing
oxymethyl
Prior art date
Application number
RU93042470/13A
Other languages
Russian (ru)
Other versions
RU2120997C1 (en
Inventor
Накадзима Мутсуо
Андо Осаму
Такахаси Судзи
Хамано Киеси
Харуяма Хидеюки
Киносита Такеси
Сато Акира
Такаматсу Ясуюки
Енокита Рицуо
Original Assignee
Санкио Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санкио Компани Лимитед filed Critical Санкио Компани Лимитед
Publication of RU93042470A publication Critical patent/RU93042470A/en
Application granted granted Critical
Publication of RU2120997C1 publication Critical patent/RU2120997C1/en

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Claims (1)

5-Амино-1-(оксиметил)-циклопентан-1,2,3,4-тетраол и 2-амино-4-(оксиметил-3а,5,6,6а-тетрагидро-4Н-циклопент-[d]-оксазол-4,5,6-тpиол, которые имеют способность ингибировать активность гидролиза сахара, особенно бета-глюкозидазы и бета-фруктофуранозидазы, и могут таким образом использоваться для лечения и профилактики опухолевых состояний, СПИДа, диабетов и ожирения, могут быть получены путем гидролиза трехазолина. 2-Амино-4-(оксиметил)-3а, 5,6,6а-тетрагидро-4Н-циклопент-[d]-оксазол-4,5,6-тpиол может быть получен также путем ферментации, используя свежевыделенные штаммы Микромоноспоры вида SANK 62390, FERM ВР-3521 и Амиколатопсиса вида SANK 60791, FERM ВР-3513.5-amino-1- (oxymethyl) -cyclopentane-1,2,3,4-tetraol and 2-amino-4- (oxymethyl-3a, 5,6,6a-tetrahydro-4H-cyclopent- [d] -oxazole -4,5,6-thiol, which have the ability to inhibit the activity of sugar hydrolysis, especially beta-glucosidase and beta-fructofuranosidase, and can thus be used to treat and prevent tumor conditions, AIDS, diabetes and obesity, can be obtained by hydrolysis of triazoline . 2-amino-4- (oxymethyl) -3a, 5,6,6a-tetrahydro-4H-cyclopent- [d] -oxazole-4,5,6-thiol can also be obtained by fermentation using freshly isolated Tammy Mikromonospory kind SANK 62390, FERM BP-3521 and Amikolatopsisa kind SANK 60791, FERM BP-3513.
RU93042470A 1991-02-15 1992-02-14 Method of producing 2-amino-4-(hydroxymethyl)-3a,5,6,6a- -tetrahydro-4h-cyclopent-[d]-oxazole-4,5,6-triol and strains of actinomyces micromonospora and amycolatopsis producing its RU2120997C1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP3-21976 1991-02-15
JP2197691 1991-02-15
JP3-132946 1991-06-04
JP3-213450 1991-08-26
JP21345091 1991-08-26
JP3-272412 1991-10-21

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU5011120 Division

Publications (2)

Publication Number Publication Date
RU93042470A true RU93042470A (en) 1997-01-20
RU2120997C1 RU2120997C1 (en) 1998-10-27

Family

ID=26359131

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93042470A RU2120997C1 (en) 1991-02-15 1992-02-14 Method of producing 2-amino-4-(hydroxymethyl)-3a,5,6,6a- -tetrahydro-4h-cyclopent-[d]-oxazole-4,5,6-triol and strains of actinomyces micromonospora and amycolatopsis producing its

Country Status (1)

Country Link
RU (1) RU2120997C1 (en)

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