RU93029440A - HC280 DNA FRAGMENT, POLYPEPTIDE, ESCHERICHIA COLI BACTERIA STRAINS - POLYPEPTIDE PRODUCERS - Google Patents

HC280 DNA FRAGMENT, POLYPEPTIDE, ESCHERICHIA COLI BACTERIA STRAINS - POLYPEPTIDE PRODUCERS

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Publication number
RU93029440A
RU93029440A RU93029440/13A RU93029440A RU93029440A RU 93029440 A RU93029440 A RU 93029440A RU 93029440/13 A RU93029440/13 A RU 93029440/13A RU 93029440 A RU93029440 A RU 93029440A RU 93029440 A RU93029440 A RU 93029440A
Authority
RU
Russia
Prior art keywords
polypeptide
escherichia coli
coli bacteria
dna fragment
producers
Prior art date
Application number
RU93029440/13A
Other languages
Russian (ru)
Other versions
RU2073718C1 (en
Inventor
В.Н. Лопарев
В.Н. Красных
В.М. Блинов
В.А. Гольцов
В.В. Зверев
Л.Л. Суханова
Г.И. Алаторцева
Original Assignee
Биотехнологическая компания "Биосервис"
Filing date
Publication date
Application filed by Биотехнологическая компания "Биосервис" filed Critical Биотехнологическая компания "Биосервис"
Priority to RU93029440A priority Critical patent/RU2073718C1/en
Priority claimed from RU93029440A external-priority patent/RU2073718C1/en
Publication of RU93029440A publication Critical patent/RU93029440A/en
Application granted granted Critical
Publication of RU2073718C1 publication Critical patent/RU2073718C1/en

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Claims (1)

Изобретение относится к биотехнологии и иммунологии. Сущность изобретения состоит в том, что получены полипептиды, обладающие способностью связывать антитела к продукту гена NS4 вируса гепатита С и предназначенные для определения антител к вирусу гепатита С, синтезируемые в штаммах бактерий Escherichia coli, трансформированных рекомбинантными плазмидами pHC280 или pHC280F, содержащими нуклеотидную последовательность гена белка NS4, свободную или слитную с последовательностью нуклеотидов гена бета-галактозидазой E-coli.The invention relates to biotechnology and immunology. The essence of the invention is that polypeptides have been obtained that have the ability to bind antibodies to the NS4 gene product of the hepatitis C virus and are designed to detect antibodies to the hepatitis C virus, synthesized in strains of Escherichia coli bacteria transformed with recombinant plasmids pHC280 or pHC280F containing the nucleotide sequence of the protein gene NS4, free or fused to the E-coli beta-galactosidase gene nucleotide sequence.
RU93029440A 1993-06-03 1993-06-03 Dna fragment hc 280 prepared by chemical synthesis, recombinant polypeptide hc 280 at molecular mass 120-130 kda showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus prepared at cultivation of the strain of bacterium escherichia coli - strain of bacterium escherichia coli - a producer of recombinant polypeptide hc 280 showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus RU2073718C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU93029440A RU2073718C1 (en) 1993-06-03 1993-06-03 Dna fragment hc 280 prepared by chemical synthesis, recombinant polypeptide hc 280 at molecular mass 120-130 kda showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus prepared at cultivation of the strain of bacterium escherichia coli - strain of bacterium escherichia coli - a producer of recombinant polypeptide hc 280 showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU93029440A RU2073718C1 (en) 1993-06-03 1993-06-03 Dna fragment hc 280 prepared by chemical synthesis, recombinant polypeptide hc 280 at molecular mass 120-130 kda showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus prepared at cultivation of the strain of bacterium escherichia coli - strain of bacterium escherichia coli - a producer of recombinant polypeptide hc 280 showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus

Publications (2)

Publication Number Publication Date
RU93029440A true RU93029440A (en) 1996-06-10
RU2073718C1 RU2073718C1 (en) 1997-02-20

Family

ID=20142670

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93029440A RU2073718C1 (en) 1993-06-03 1993-06-03 Dna fragment hc 280 prepared by chemical synthesis, recombinant polypeptide hc 280 at molecular mass 120-130 kda showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus prepared at cultivation of the strain of bacterium escherichia coli - strain of bacterium escherichia coli - a producer of recombinant polypeptide hc 280 showing capability to bind antibodies to gene-encoding protein ns4 of hepatitis c virus

Country Status (1)

Country Link
RU (1) RU2073718C1 (en)

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