RU93014480A - METHOD FOR PRODUCING COLLAGEN SPONGE - Google Patents

METHOD FOR PRODUCING COLLAGEN SPONGE

Info

Publication number
RU93014480A
RU93014480A RU93014480/04A RU93014480A RU93014480A RU 93014480 A RU93014480 A RU 93014480A RU 93014480/04 A RU93014480/04 A RU 93014480/04A RU 93014480 A RU93014480 A RU 93014480A RU 93014480 A RU93014480 A RU 93014480A
Authority
RU
Russia
Prior art keywords
collagen
sponge
washing
acetic acid
collagen sponge
Prior art date
Application number
RU93014480/04A
Other languages
Russian (ru)
Other versions
RU2039766C1 (en
Inventor
И.В. Калеватов
Ю.К. Кириленко
И.Л. Лазарева
В.Д. Махонин
В.Н. Соловьев
Ю.А. Тихонов
Original Assignee
Товарищество с ограниченной ответственностью - Научно-производственное предприятие "КОПО"
Filing date
Publication date
Application filed by Товарищество с ограниченной ответственностью - Научно-производственное предприятие "КОПО" filed Critical Товарищество с ограниченной ответственностью - Научно-производственное предприятие "КОПО"
Priority to RU93014480A priority Critical patent/RU2039766C1/en
Priority claimed from RU93014480A external-priority patent/RU2039766C1/en
Application granted granted Critical
Publication of RU2039766C1 publication Critical patent/RU2039766C1/en
Publication of RU93014480A publication Critical patent/RU93014480A/en

Links

Claims (1)

Изобретение относится к способу получения коллагеновой криоструктурированной губки из коллагенсодержащего сырья и включает стадии: промывку, измельчение, щелочно-солевую обработку сырья, промывку водой, набухание в уксусной кислоте, промывку водой до получения рН 2,5 - 4, разволокнение с одновременным высаживанием волокон коллагена при рН 5,5, отжатие массы, получение 3%-ной дисперсии в 0,5 - 0,7%-ном растворе NaOH, добавление уксусной кислоты до рН 4,2 - 4,5, разлив в поддоны, замораживание, размораживание и сушку. Полученную коллагеновую губку используют в медицине, в частности в качестве повязок для ожоговых ран, губка отличается высокими физико-механическими показателями.The invention relates to a method for producing a collagen cryostructured sponge from collagen-containing raw materials and includes the steps of washing, grinding, alkaline-salt processing of the raw materials, washing with water, swelling in acetic acid, washing with water until a pH of 2.5 - 4 is obtained, razvolka with simultaneous planting of collagen fibers at pH 5.5, squeezing the mass, obtaining a 3% dispersion in a 0.5 - 0.7% NaOH solution, adding acetic acid to a pH of 4.2 - 4.5, spilling into trays, freezing, thawing and drying. The resulting collagen sponge is used in medicine, in particular as a dressing for burn wounds, the sponge is characterized by high physical and mechanical properties.
RU93014480A 1993-03-19 1993-03-19 Process for preparing collagen sponge RU2039766C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU93014480A RU2039766C1 (en) 1993-03-19 1993-03-19 Process for preparing collagen sponge

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU93014480A RU2039766C1 (en) 1993-03-19 1993-03-19 Process for preparing collagen sponge

Publications (2)

Publication Number Publication Date
RU2039766C1 RU2039766C1 (en) 1995-07-20
RU93014480A true RU93014480A (en) 1997-01-10

Family

ID=20138940

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93014480A RU2039766C1 (en) 1993-03-19 1993-03-19 Process for preparing collagen sponge

Country Status (1)

Country Link
RU (1) RU2039766C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2329181B (en) * 1997-09-11 2002-03-13 Johnson & Johnson Medical Bioabsorbable Wound Dressing Materials

Similar Documents

Publication Publication Date Title
US4948540A (en) Method of preparing collagen dressing sheet material
Gorham et al. Effect of chemical modifications on the susceptibility of collagen to proteolysis. II. Dehydrothermal crosslinking
US5093474A (en) Process for the production of gelatin from fish skins
CN101234216B (en) Collagen base freezing gel suitable for biological medical material and preparation thereof
US4279812A (en) Process for preparing macromolecular biologically active collagen
CA2258990C (en) Use of oxidized cellulose and complexes thereof for chronic wound healing
AU573626B2 (en) Protein/polysaccharide complexes as wound dressing
JPS61122222A (en) Hemostatic agent composed of collagen or gelatin and protamine
EP0365108A3 (en) Low water content polyvinyl alcohol hydrogel and artificial cartilage
JPS59133276A (en) Manufacture of bonded collagen fiber sheet
JPH0461862A (en) Collagen fiber hemostatic material and its manufacture
CN1197631C (en) Construction method for skin tissue engineering rack containing epidermal growth factor
CN1210019A (en) Medical collagen sponge and manufacture thereof
JPS6250498B2 (en)
RU93014480A (en) METHOD FOR PRODUCING COLLAGEN SPONGE
CN109265535A (en) The preparation method of collagen
CN108452366A (en) A kind of gelatin-compounded bleeding-stopping dressing of cod skin and preparation method thereof
JPS6363700A (en) Production of acid-soluble collagen having high gel strength
ATE51345T1 (en) PROCESS FOR PRODUCTION OF CELLULOSE MODIFIED TO IMPROVE ABSORBENT PROPERTIES.
US3075961A (en) Reconstitution of native collagen fiber from acid precursor gelatin
CN1027599C (en) Process for producing medical non-woven cloth with organism function and products thereof
SU1108095A2 (en) Method of obtaining fish glue
RU2063411C1 (en) PROCESS FOR PREPARING γ-FRACTION OF GELATIN
RU2002805C1 (en) Method of collagen-containing material processing
RU2001921C1 (en) Composition for fibrous porous material production