RU92016550A - Тетрагидроизохинолинилкарбаматы 1,2,3,3а,8,8a-гексагидро-1,3a-8-три-метилпирроло(2,3-b)индола, фармацевтическая композиция и способ лечения - Google Patents
Тетрагидроизохинолинилкарбаматы 1,2,3,3а,8,8a-гексагидро-1,3a-8-три-метилпирроло(2,3-b)индола, фармацевтическая композиция и способ леченияInfo
- Publication number
- RU92016550A RU92016550A RU92016550/33A RU92016550A RU92016550A RU 92016550 A RU92016550 A RU 92016550A RU 92016550/33 A RU92016550/33 A RU 92016550/33A RU 92016550 A RU92016550 A RU 92016550A RU 92016550 A RU92016550 A RU 92016550A
- Authority
- RU
- Russia
- Prior art keywords
- hexahydro
- tetrahydroisohinolinilkarbamaty
- methylpirrolo
- indola
- tri
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- KLJZEHNRALYISE-UHFFFAOYSA-N 3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indole Chemical compound C1=CC=C2C3(C)CCN(C)C3N(C)C2=C1 KLJZEHNRALYISE-UHFFFAOYSA-N 0.000 claims 1
- YQLFNHRHQDLFTQ-UHFFFAOYSA-M C1=CC=C2C(NC(=O)[O-])NCCC2=C1 Chemical class C1=CC=C2C(NC(=O)[O-])NCCC2=C1 YQLFNHRHQDLFTQ-UHFFFAOYSA-M 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 230000001713 cholinergic Effects 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
Claims (1)
- Описываются тетрагидроизохинолинилкарбаматы 1,2,3,3а,8,8а-гексагидро-1,3а, 8-триметилпирроло(2,3-в)индола общей формулы, в которой R - водород; низший алкил, X - водород, галоген; низший алкоксил или гидроксил, которые полезны для облегчения дисфункций памяти, характеризующихся холинергическим дефицитом.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1990/003552 WO1992000072A1 (en) | 1990-06-27 | 1990-06-27 | Tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole |
Publications (2)
Publication Number | Publication Date |
---|---|
RU92016550A true RU92016550A (ru) | 1995-06-19 |
RU2124516C1 RU2124516C1 (ru) | 1999-01-10 |
Family
ID=22220922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU92016550A RU2124516C1 (ru) | 1990-06-27 | 1990-06-27 | Тетрагидроизохинолинкарбаматы 1,2,3,3а,8,8а-гексагидро-1,3а-8-триметилпирроло (2,3-b)индола, фармацевтическая композиция и способ ингибирования ацетилхолинэстеразы |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0538248B1 (ru) |
KR (1) | KR0172971B1 (ru) |
AT (1) | ATE163183T1 (ru) |
AU (1) | AU649953B2 (ru) |
BG (1) | BG61188B1 (ru) |
DE (1) | DE69032046T2 (ru) |
DK (1) | DK0538248T3 (ru) |
ES (1) | ES2113859T3 (ru) |
FI (1) | FI97229C (ru) |
GE (1) | GEP19991747B (ru) |
LT (1) | LT3598B (ru) |
LV (1) | LV10189B (ru) |
MC (1) | MC2287A1 (ru) |
NO (1) | NO179910C (ru) |
RO (1) | RO110501B1 (ru) |
RU (1) | RU2124516C1 (ru) |
SG (1) | SG70968A1 (ru) |
WO (1) | WO1992000072A1 (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
IT1271679B (it) * | 1994-07-18 | 1997-06-04 | Mediolanum Farmaceutici Srl | Derivati del fenilcarbammato atti all'impiego come anticolinesterasici |
US5665880A (en) * | 1996-10-31 | 1997-09-09 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseretholes |
US5677457A (en) * | 1996-12-19 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseroline ethers |
DK1149079T3 (da) * | 1999-02-04 | 2004-08-16 | Sk Corp | Tetrahydroisoquinolinalkanolderivater og farmaceutiske præparater indeholdende samme |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
DK168069B1 (da) * | 1987-11-11 | 1994-01-31 | Hoffmann La Roche | Isoquinolinderivater og en fremgangsmaade til fremstilling af octahydroisoquinoliner ud fra derivaterne |
US4914102A (en) * | 1989-09-28 | 1990-04-03 | Hoechst Roussel Pharmaceuticals, Inc. | N-aminocarbamates related to physostigmine, pharmacentical compositions and use |
AU634380B2 (en) * | 1990-05-17 | 1993-02-18 | Hoechst-Roussel Pharmaceuticals Incorporated | Alpha-oxopyrrolo(2,3-b)indole acetic acids, esters, amides and related analogs, a process for their preparation and their use as medicaments |
-
1990
- 1990-06-27 AT AT90910230T patent/ATE163183T1/de not_active IP Right Cessation
- 1990-06-27 RU RU92016550A patent/RU2124516C1/ru active
- 1990-06-27 WO PCT/US1990/003552 patent/WO1992000072A1/en active IP Right Grant
- 1990-06-27 RO RO92-01561A patent/RO110501B1/ro unknown
- 1990-06-27 DE DE69032046T patent/DE69032046T2/de not_active Expired - Fee Related
- 1990-06-27 KR KR1019920703313A patent/KR0172971B1/ko not_active IP Right Cessation
- 1990-06-27 SG SG1996003071A patent/SG70968A1/en unknown
- 1990-06-27 EP EP90910230A patent/EP0538248B1/en not_active Expired - Lifetime
- 1990-06-27 ES ES90910230T patent/ES2113859T3/es not_active Expired - Lifetime
- 1990-06-27 MC MC90@@D patent/MC2287A1/xx unknown
- 1990-06-27 DK DK90910230T patent/DK0538248T3/da active
- 1990-06-27 AU AU59313/90A patent/AU649953B2/en not_active Ceased
-
1992
- 1992-12-23 NO NO925008A patent/NO179910C/no not_active IP Right Cessation
- 1992-12-23 BG BG97231A patent/BG61188B1/bg unknown
- 1992-12-23 FI FI925872A patent/FI97229C/fi active
-
1993
- 1993-06-15 LV LVP-93-575A patent/LV10189B/en unknown
- 1993-07-29 GE GEAP19931278A patent/GEP19991747B/en unknown
- 1993-09-03 LT LTIP923A patent/LT3598B/lt not_active IP Right Cessation
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR0179054B1 (en) | Heterocyclic-cyclic amine derivatives | |
NZ232589A (en) | Pyrrole-substituted condensed indole derivatives and pharmaceutical compositions | |
ATE69951T1 (de) | Cancerostatisches mittel. | |
CA2197793A1 (en) | New multimerizing agents | |
GR3022034T3 (en) | Dihydro-isoquinoline derivates | |
CA2168097A1 (en) | Substituted 2-aminotetralins | |
CA2276455A1 (en) | Phthalazinones | |
CA2323150A1 (en) | New porphyrins and their use | |
DE3680101D1 (de) | Waermespeicherzusammensetzung. | |
DK0558449T3 (da) | Chelatkomplekser og fremgangsmåde til deres fremstilling | |
RU92016550A (ru) | Тетрагидроизохинолинилкарбаматы 1,2,3,3а,8,8a-гексагидро-1,3a-8-три-метилпирроло(2,3-b)индола, фармацевтическая композиция и способ лечения | |
MXPA02009549A (es) | Imidazopiridinas triciclicas. | |
CA2298820A1 (en) | The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives | |
BG97231A (bg) | Тетрахидроизохинолинилкарбамати на 1,2,3,3а,8,8а-хексахидро- 1,3а,8-триметилпироло(2,3-в)индол | |
FI923812A0 (fi) | Anordning foer aostadkommande av en rymdladdning i atmosfaeren. | |
EP0457193A3 (en) | Coolant composition for the local treatment of burns | |
NO880405D0 (no) | Fremgangsmaate til fremstilling av 3-fenyl-7h-tiazolo-/3,2-b//1,2,4/-tiazine-7-oner. | |
RU93052708A (ru) | Производные 5-гетероилиндола | |
SE9000348D0 (sv) | Foerfarande foer framstaellning av en faellningskemikalie | |
TH9052EX (th) | ฐานรองรับตัวเตาก๊าซ | |
IT8228925V0 (it) | Tavolo per picnic e/o campeggio, nonche' sgabello, riducibile inpochissimo volume | |
BR7001591U (pt) | Copo refratario | |
FI900447A0 (fi) | Anordning foer foerande av plantor i jord. |