RU92016444A - PREPARATION OF DERIVATIVES OF PIPERIDINES AND DERIVATIVES OF PIPERIDINE - Google Patents

PREPARATION OF DERIVATIVES OF PIPERIDINES AND DERIVATIVES OF PIPERIDINE

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Publication number
RU92016444A
RU92016444A RU92016444/04A RU92016444A RU92016444A RU 92016444 A RU92016444 A RU 92016444A RU 92016444/04 A RU92016444/04 A RU 92016444/04A RU 92016444 A RU92016444 A RU 92016444A RU 92016444 A RU92016444 A RU 92016444A
Authority
RU
Russia
Prior art keywords
derivatives
piperidines
piperidine
preparation
formula
Prior art date
Application number
RU92016444/04A
Other languages
Russian (ru)
Other versions
RU2077531C1 (en
Inventor
М.Годек Денниз
Дж.Роузен Терри
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Priority claimed from PCT/US1991/002541 external-priority patent/WO1991018878A1/en
Publication of RU92016444A publication Critical patent/RU92016444A/en
Application granted granted Critical
Publication of RU2077531C1 publication Critical patent/RU2077531C1/en

Links

Claims (1)

Изобретение относится к получению замещенных пиперидинов формулы I
Figure 00000001

Раскрыты новые способы получения и расщепления замещенных пиперидинов формулы (1), где R1 и R2 определены в описании, и родственных соединений, так же как и новых промежуточных, используемых в таких способах.The invention relates to the production of substituted piperidines of the formula I
Figure 00000001

New methods for producing and cleaving substituted piperidines of formula (1), where R 1 and R 2 are defined in the description, and related compounds, as well as new intermediates used in such methods, are disclosed.
RU9192016444A 1990-05-31 1991-04-12 Method for production of substituted (3-benzylamino)-2-phenyl piperidines, substituted (3-benzylamino)-2-phenyl pyridine and method for its production RU2077531C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53126590A 1990-05-31 1990-05-31
US531.265 1990-05-31
PCT/US1991/002541 WO1991018878A1 (en) 1990-05-31 1991-04-12 Preparation of substituted piperidines

Publications (2)

Publication Number Publication Date
RU92016444A true RU92016444A (en) 1995-10-20
RU2077531C1 RU2077531C1 (en) 1997-04-20

Family

ID=24116944

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9192016444A RU2077531C1 (en) 1990-05-31 1991-04-12 Method for production of substituted (3-benzylamino)-2-phenyl piperidines, substituted (3-benzylamino)-2-phenyl pyridine and method for its production

Country Status (26)

Country Link
EP (1) EP0532515B1 (en)
JP (2) JPH0794439B2 (en)
KR (1) KR0160142B1 (en)
CN (2) CN1037768C (en)
AT (1) ATE144498T1 (en)
AU (1) AU648558B2 (en)
BR (1) BR9106518A (en)
CA (1) CA2080249C (en)
CZ (1) CZ284663B6 (en)
DE (1) DE69122866T2 (en)
DK (1) DK0532515T3 (en)
ES (1) ES2093099T3 (en)
FI (1) FI101376B (en)
GR (1) GR3022079T3 (en)
HU (1) HU226529B1 (en)
IE (1) IE911841A1 (en)
IL (3) IL98256A (en)
MY (1) MY107819A (en)
NO (1) NO180083C (en)
NZ (2) NZ250217A (en)
PL (2) PL169187B1 (en)
PT (1) PT97796B (en)
RU (1) RU2077531C1 (en)
WO (1) WO1991018878A1 (en)
YU (1) YU48030B (en)
ZA (1) ZA914133B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA41251C2 (en) * 1990-01-04 2001-09-17 Пфайзер, Інк. Hydrogenated nitrogen-containing heterocyclic substances, piperidine derivatives, pharmaceutical composition and method for inhibiting activity of p substance
US5332817A (en) * 1990-01-04 1994-07-26 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
BR9205807A (en) * 1991-03-26 1994-06-28 Pfizer Stereo-selective preparation of substituted piperidines
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
DK0613458T3 (en) * 1991-11-12 1998-02-09 Pfizer Acyclic ethylenediamine derivatives as substance P receptor antagonists
WO1994013663A1 (en) * 1992-12-10 1994-06-23 Pfizer Inc. Aminomethylene substituted non-aromatic heterocycles and use as substance p antagonists
ATE155456T1 (en) 1993-05-28 1997-08-15 Pfizer METHOD FOR THE PRODUCTION AND OPTICAL RESOLUTION OF 2-PHENYL-3-AMINOPIPERIDINE
TW397825B (en) * 1994-10-14 2000-07-11 Novartis Ag Aroyl-piperidine derivatives
FR2728169A1 (en) 1994-12-19 1996-06-21 Oreal USE OF A SUBSTANCE P ANTAGONIST FOR THE TREATMENT OF PRURITUS AND EYE OR PALPEBRAL DYSESTHESIA
FR2728166A1 (en) 1994-12-19 1996-06-21 Oreal TOPICAL COMPOSITION CONTAINING AN ANTAGONIST OF SUBSTANCE P
FR2728165A1 (en) 1994-12-19 1996-06-21 Oreal USE OF AN ANTAGONIST OF SUBSTANCE P FOR THE TREATMENT OF SKIN REDNESS OF NEUROGENIC ORIGIN
FR2741262B1 (en) 1995-11-20 1999-03-05 Oreal USE OF A TNF-ALPHA ANTAGONIST FOR THE TREATMENT OF CUTANEOUS REDNESS OF NEUROGENIC ORIGIN
JP2002506459A (en) 1997-06-27 2002-02-26 メルク シヤープ エンド ドーム リミテツド Substituted 3- (benzylamino) piperidine derivatives and their use as therapeutics
EP1098881A1 (en) * 1998-07-21 2001-05-16 Syngenta Participations AG 3-substituted pyridine compounds and related synthesis
JP2011016751A (en) * 2009-07-08 2011-01-27 Sumitomo Chemical Co Ltd Method for producing optically active 3-aminopiperidine-1-carboxylate compound and intermediate used for the production method
CN111808017B (en) * 2020-08-05 2023-11-28 国家纳米科学中心 Nitrogen-containing heterocyclic compound, and preparation method and application thereof
CN116162055B (en) * 2023-03-10 2023-09-12 山东汇智药物研究有限公司 Method for preparing piperidine derivative from pyridine N-oxide derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125170A (en) * 1976-04-12 1977-10-20 Yoshitomi Pharmaceut Ind Ltd Pyridine derivatives
CA1160229A (en) * 1979-03-13 1984-01-10 Pieter T. Haken Pyridyliminomethylbenzene derivatives
GB2056974B (en) * 1979-07-19 1984-02-29 Shell Int Research Heterocyclic acylamino compounds having fungicidal herbicidal and plant-growth regulating properties
CA1231710A (en) * 1979-07-19 1988-01-19 Haken Pieter Ten Heterocyclic compounds having fungicidal, herbicidal and plant-growth regulating properties
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
US4552960A (en) * 1983-06-20 1985-11-12 Eli Lilly And Company Fungicidal amines
FR2662696A2 (en) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Serotonin antagonists, their preparation and medicaments containing them
UA41251C2 (en) * 1990-01-04 2001-09-17 Пфайзер, Інк. Hydrogenated nitrogen-containing heterocyclic substances, piperidine derivatives, pharmaceutical composition and method for inhibiting activity of p substance

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