RU2741645C2 - Способы доставки агента в икринки рыб - Google Patents

Способы доставки агента в икринки рыб Download PDF

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RU2741645C2
RU2741645C2 RU2017142635A RU2017142635A RU2741645C2 RU 2741645 C2 RU2741645 C2 RU 2741645C2 RU 2017142635 A RU2017142635 A RU 2017142635A RU 2017142635 A RU2017142635 A RU 2017142635A RU 2741645 C2 RU2741645 C2 RU 2741645C2
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guanidine
fish
egg
eggs
agent
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RU2017142635A
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Russian (ru)
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RU2017142635A3 (https=
RU2017142635A (ru
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Тен Цао ВОНГ
Йонатан ЗОХАР
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Юниверсити Оф Мэрилэнд Балтимор Каунти
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/05Animals modified by non-integrating nucleic acids, e.g. antisense, RNAi, morpholino, episomal vector, for non-therapeutic purpose
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/20Animals treated with compounds which are neither proteins nor nucleic acids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/40Fish
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/323Chemical structure of the sugar modified ring structure
    • C12N2310/3233Morpholino-type ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • C12N2320/32Special delivery means, e.g. tissue-specific
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/40Monitoring or fighting invasive species

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2017142635A 2015-05-19 2016-05-17 Способы доставки агента в икринки рыб RU2741645C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562163511P 2015-05-19 2015-05-19
US62/163,511 2015-05-19
US201662274958P 2016-01-05 2016-01-05
US62/274,958 2016-01-05
PCT/US2016/032873 WO2016187198A2 (en) 2015-05-19 2016-05-17 Methods of agent delivery into eggs and embryos of egg-producing aquatic animals for drug screening, agent toxicity assay and production of infertile fish

Publications (3)

Publication Number Publication Date
RU2017142635A RU2017142635A (ru) 2019-06-20
RU2017142635A3 RU2017142635A3 (https=) 2019-12-16
RU2741645C2 true RU2741645C2 (ru) 2021-01-28

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RU2017142635A RU2741645C2 (ru) 2015-05-19 2016-05-17 Способы доставки агента в икринки рыб

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US (1) US10709119B2 (https=)
EP (1) EP3297429A2 (https=)
JP (1) JP6756960B2 (https=)
CN (1) CN108040459B (https=)
AU (1) AU2016265929B2 (https=)
BR (1) BR112017024662A2 (https=)
CL (1) CL2017002864A1 (https=)
DK (1) DK180094B1 (https=)
IL (1) IL255338B (https=)
MX (1) MX386910B (https=)
RU (1) RU2741645C2 (https=)
WO (1) WO2016187198A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2929496C (en) 2013-11-15 2022-08-23 University Of Maryland Baltimore County Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
EP3723479B1 (en) * 2017-12-15 2024-05-22 ACD Pharmaceuticals AS Methods for the production of sterile fish
GEP20237545B (en) * 2018-12-17 2023-10-10 Alfred Wegener Inst Helmholtz Zentrum Fuer Polar Und Meeres Forschung Method for producing caviar or caviar-like product from living, mature eggs of fish or crustaceans, and products of this kind

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040250308A1 (en) * 2003-05-19 2004-12-09 Sun Piera S. Method for direct nucleic acid uptake
US7935816B2 (en) * 2007-10-25 2011-05-03 Gene Tools, Llc Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo
EP2535404A1 (en) * 2010-02-09 2012-12-19 National University Corporation Hokkaido University Method for acquiring genetically identical gamete from lethal fish haploid-derived germ cell via germ line chimera
WO2013054123A1 (en) * 2011-10-11 2013-04-18 The Royal Veterinary College Methods
RU2504389C2 (ru) * 2012-02-16 2014-01-20 Федеральное государственное бюджетное учреждение науки Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина Российской академии наук (ИБФМ РАН) СПОСОБ ПОРОФОРМИРОВАНИЯ В МЕМБРАНАХ КЛЕТОК ПЕЧЕНИ С ПОМОЩЬЮ ОБРАБОТКИ ИХ ГЕМОЛИЗИНОМ II Bacillus cereus

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7194978B2 (en) 2003-08-22 2007-03-27 University Of Maryland Biotechnology Institute Inducing sterility in fish by disrupting the development of the GnRH system
CN1294808C (zh) 2003-09-26 2007-01-17 中国科学院水生生物研究所 不育转基因鱼的制备方法
CN1274822C (zh) 2004-02-19 2006-09-13 武汉康祥科技发展有限公司 活体化学诱导鱼类雌核发育方法
CN101553210A (zh) * 2006-09-20 2009-10-07 奈克斯特安全有限公司 经吸入输送药物的方法和系统
JP2010516277A (ja) 2007-01-26 2010-05-20 シナジェバ・バイオファーマ・コーポレイション トリにおける導入遺伝子発現
US8383880B2 (en) 2009-02-18 2013-02-26 Academia Sinica Infertility control of genetically modified fish
WO2011018798A2 (en) * 2009-08-14 2011-02-17 Indian Association For The Cultivation Of Science Morpholino-based antisense agent
US9534235B2 (en) 2011-02-01 2017-01-03 Purdue Research Foundation Efficient sterilization of fish by disruption of germ cell development
US9538734B2 (en) 2013-03-12 2017-01-10 The General Hospital Corporation Germ cell ablation compounds and uses thereof
CA2929496C (en) * 2013-11-15 2022-08-23 University Of Maryland Baltimore County Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040250308A1 (en) * 2003-05-19 2004-12-09 Sun Piera S. Method for direct nucleic acid uptake
US7935816B2 (en) * 2007-10-25 2011-05-03 Gene Tools, Llc Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo
EP2535404A1 (en) * 2010-02-09 2012-12-19 National University Corporation Hokkaido University Method for acquiring genetically identical gamete from lethal fish haploid-derived germ cell via germ line chimera
WO2013054123A1 (en) * 2011-10-11 2013-04-18 The Royal Veterinary College Methods
RU2504389C2 (ru) * 2012-02-16 2014-01-20 Федеральное государственное бюджетное учреждение науки Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина Российской академии наук (ИБФМ РАН) СПОСОБ ПОРОФОРМИРОВАНИЯ В МЕМБРАНАХ КЛЕТОК ПЕЧЕНИ С ПОМОЩЬЮ ОБРАБОТКИ ИХ ГЕМОЛИЗИНОМ II Bacillus cereus

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALHAKAMY N. A. & BERKLAND C. J. "Polyarginine Molecular Weight Determines Transfection Efficiency of Calcium Condensed Complexes." Molecular Pharmaceutics, 2013, 10(5), pp.1940-1948. doi:10.1021/mp3007117. *
ALHAKAMY N. A. & BERKLAND C. J. "Polyarginine Molecular Weight Determines Transfection Efficiency of Calcium Condensed Complexes." Molecular Pharmaceutics, 2013, 10(5), pp.1940-1948. doi:10.1021/mp3007117. WEIDINGER G. et al. "dead end, a Novel Vertebrate Germ Plasm Component, Is Required for Zebrafish Primordial Germ Cell Migration and Survival". Current Biology, 2003, v.13, pp.1429-1434. *
KAIS В. ET AL.: "DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-implications for the fish embryo test (FET)", AQUAT TOXICOL, 2013, v.140-141, p.229-238, doi: 10.1016/j.aquatox.2013.05.022. *
WEIDINGER G. et al. "dead end, a Novel Vertebrate Germ Plasm Component, Is Required for Zebrafish Primordial Germ Cell Migration and Survival". Current Biology, 2003, v.13, pp.1429-1434. *
WONG T. T., ZOHAR Y. "Production of reproductively sterile fish: A mini- review of germ cell elimination technologies", GEN COMP ENDOCRINOL. Epub 09.01.2015, v.221, p.1-21, doi: 10.1016/j.ygcen.2014.12.012. *
WONG T. T., ZOHAR Y. "Production of reproductively sterile fish: A mini- review of germ cell elimination technologies", GEN COMP ENDOCRINOL. Epub 09.01.2015, v.221, p.1-21, doi: 10.1016/j.ygcen.2014.12.012. KAIS В. ET AL.: "DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-implications for the fish embryo test (FET)", AQUAT TOXICOL, 2013, v.140-141, p.229-238, doi: 10.1016/j.aquatox.2013.05.022. *

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Publication number Publication date
WO2016187198A3 (en) 2017-01-12
BR112017024662A2 (pt) 2018-09-11
IL255338A0 (en) 2017-12-31
AU2016265929A1 (en) 2017-11-09
US10709119B2 (en) 2020-07-14
MX386910B (es) 2025-03-19
US20180295817A1 (en) 2018-10-18
DK201770877A1 (en) 2017-11-27
NZ737306A (en) 2025-02-28
IL255338B (en) 2022-05-01
MX2017014856A (es) 2018-04-20
CN108040459A (zh) 2018-05-15
AU2016265929B2 (en) 2022-03-31
EP3297429A2 (en) 2018-03-28
RU2017142635A3 (https=) 2019-12-16
RU2017142635A (ru) 2019-06-20
CL2017002864A1 (es) 2018-05-18
JP2018515116A (ja) 2018-06-14
CA2984644A1 (en) 2016-11-24
JP6756960B2 (ja) 2020-09-16
CN108040459B (zh) 2021-09-21
DK180094B1 (en) 2020-04-27
WO2016187198A2 (en) 2016-11-24

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