RU2723034C2 - Новые полипептиды со специфическим связыванием и пути их применения - Google Patents

Новые полипептиды со специфическим связыванием и пути их применения Download PDF

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RU2723034C2
RU2723034C2 RU2016149596A RU2016149596A RU2723034C2 RU 2723034 C2 RU2723034 C2 RU 2723034C2 RU 2016149596 A RU2016149596 A RU 2016149596A RU 2016149596 A RU2016149596 A RU 2016149596A RU 2723034 C2 RU2723034 C2 RU 2723034C2
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lipocalin
mutein
binding
seq
fusion protein
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RU2016149596A
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RU2016149596A3 (enExample
RU2016149596A (ru
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Марлон ХИННЕР
Александер ВИДЕНМАН
Андреа АЛЛЕРСДОРФЕР
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ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/525Tumor necrosis factor [TNF]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]

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  • Immunology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Food Science & Technology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
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  • Rheumatology (AREA)
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RU2016149596A 2014-05-22 2015-05-20 Новые полипептиды со специфическим связыванием и пути их применения RU2723034C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14169488.5 2014-05-22
EP14169488 2014-05-22
PCT/EP2015/061034 WO2015177175A2 (en) 2014-05-22 2015-05-20 Novel specific-binding polypeptides and uses thereof

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RU2016149596A RU2016149596A (ru) 2018-06-26
RU2016149596A3 RU2016149596A3 (enExample) 2019-01-22
RU2723034C2 true RU2723034C2 (ru) 2020-06-08

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US (2) US10774119B2 (enExample)
EP (2) EP3145945B1 (enExample)
JP (2) JP6753784B2 (enExample)
KR (1) KR20170004011A (enExample)
CN (2) CN106573964B (enExample)
AU (2) AU2015261968B2 (enExample)
BR (1) BR112016027024A2 (enExample)
CA (2) CA2949405C (enExample)
DK (1) DK3145945T3 (enExample)
ES (1) ES2823563T3 (enExample)
MX (2) MX384363B (enExample)
RU (1) RU2723034C2 (enExample)
SG (2) SG10201912019WA (enExample)
WO (1) WO2015177175A2 (enExample)

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CN109180789B (zh) * 2018-09-27 2022-08-19 上海揽微赛尔生物科技有限公司 一种寡肽及制药应用
CN109096373B (zh) * 2018-09-27 2022-06-21 江苏亨瑞生物医药科技有限公司 合成寡肽及其用途
CN109096374B (zh) * 2018-09-27 2022-11-18 深圳乐土沃森精准医疗有限公司 一种抑制肺癌转移的合成寡肽
CN109206485B (zh) * 2018-09-27 2022-04-08 山东聚胜生物科技有限公司 一种防治肺癌转移的寡肽
CN113939307A (zh) 2019-03-29 2022-01-14 皮里斯制药有限公司 脂质运载蛋白突变蛋白的吸入施用
JP2023524125A (ja) * 2020-05-05 2023-06-08 ヤンセン バイオテツク,インコーポレーテツド 抗il23特異的抗体によるクローン病の治療方法
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CN113621050A (zh) 2021-11-09
MX2021008318A (es) 2021-08-05
ES2823563T3 (es) 2021-05-07
AU2019201007A1 (en) 2019-03-07
CA2949405C (en) 2023-08-01
JP2021035358A (ja) 2021-03-04
RU2016149596A3 (enExample) 2019-01-22
EP3145945B1 (en) 2020-07-15
KR20170004011A (ko) 2017-01-10
US20200377563A1 (en) 2020-12-03
CA2949405A1 (en) 2015-11-26
DK3145945T3 (da) 2020-09-28
US20170107266A1 (en) 2017-04-20
AU2015261968A1 (en) 2016-11-24
EP3789397B1 (en) 2023-12-06
MX384363B (es) 2025-03-14
CA3170782A1 (en) 2015-11-26
WO2015177175A3 (en) 2016-02-18
RU2016149596A (ru) 2018-06-26
BR112016027024A2 (pt) 2017-10-31
JP6753784B2 (ja) 2020-09-09
SG10201912019WA (en) 2020-02-27
AU2015261968B2 (en) 2018-11-22
WO2015177175A2 (en) 2015-11-26
JP7084965B2 (ja) 2022-06-15
CN106573964B (zh) 2021-07-16
SG11201609274SA (en) 2016-12-29
JP2017518748A (ja) 2017-07-13
CN106573964A (zh) 2017-04-19
EP3789397A1 (en) 2021-03-10
EP3145945A2 (en) 2017-03-29
MX2016015235A (es) 2017-06-29
US10774119B2 (en) 2020-09-15
US11345728B2 (en) 2022-05-31
AU2019201007B2 (en) 2020-10-22

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